Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 • 7,902 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Plat-E: an efficient and stable system for transient packaging of retroviruses

2000 • 1,614 citations

Complement

2001 • 1,457 citations

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

2001 • 1,212 citations

Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances Expression of Transgenes Delivered by Retroviral Vectors

1999 • 1,007 citations

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

1996 • 849 citations

Treatment of Murine Lupus with CTLA4Ig

1994 • 683 citations

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus.

1993 • 637 citations

PATHOGENESIS OF THE GLOMERULONEPHRITIS OF NZB/W MICE

1968 • 622 citations

Localization of Distinct Peyer's Patch Dendritic Cell Subsets and Their Recruitment by Chemokines Macrophage Inflammatory Protein (Mip)-3α, Mip-3β, and Secondary Lymphoid Organ Chemokine

2000 • 578 citations

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.

1996 • 516 citations

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

1985 • 466 citations

Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis.

1977 • 409 citations

Constitutive Presentation of a Natural Tissue Autoantigen Exclusively by Dendritic Cells in the Draining Lymph Node

2002 • 387 citations

Woodchuck Hepatitis Virus Contains a Tripartite Posttranscriptional Regulatory Element

1998 • 354 citations

Synovium as a source of increased amino-terminal parathyroid hormone-related protein expression in rheumatoid arthritis. A possible role for locally produced parathyroid hormone-related protein in the pathogenesis of rheumatoid arthritis.

1998 • 340 citations

The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus.

1994 • 307 citations

Immunotherapy through TCR gene transfer

2001 • 287 citations

T-cell-receptor gene therapy

2002 • 266 citations

Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: Antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus

2000 • 249 citations

Efficient screening of retroviral cDNA expression libraries.

1995 • 244 citations

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.

1993 • 234 citations

Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus.

1996 • 221 citations

B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events.

1996 • 220 citations

Nucleosomes are major T and B cell autoantigens in systemic lupus erythematosus

2000 • 191 citations

Pivotal Role of Dendritic Cell–derived CXCL10 in the Retention of T Helper Cell 1 Lymphocytes in Secondary Lymph Nodes

2002 • 186 citations

Antigen-specific T cell–mediated gene therapy in collagen-induced arthritis

2001 • 183 citations

Genetic Dissection of Sle Pathogenesis:Sle3on Murine Chromosome 7 Impacts T Cell Activation, Differentiation, and Cell Death

1999 • 176 citations

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

2001 • 171 citations

Major peptide autoepitopes for nucleosome-specific T cells of human lupus

1999 • 167 citations

CTLA4Ig inhibits T cell–dependent B-cell maturation in murine systemic lupus erythematosus

2000 • 166 citations

Aberrant High Expression of B Lymphocyte Chemokine (Blc/Cxcl13) by C11b+Cd11c+ Dendritic Cells in Murine Lupus and Preferential Chemotaxis of B1 Cells towards Blc

2001 • 161 citations

CTLA4Ig TREATMENT AMELIORATES THE LETHALITY OF MURINE GRAFT-VERSUS-HOST DISEASE ACROSS MAJOR HISTOCOMPATIBILITY COMPLEX BARRIERS

1994 • 123 citations

Stability of the Higher-Order Structure of Chicken-Erythrocyte Chromatin in Solution

1981 • 119 citations

Cd4+ T Cells from Lupus-Prone Mice Are Hyperresponsive to T Cell Receptor Engagement with Low and High Affinity Peptide Antigens

2001 • 116 citations

Systemic Lupus Erythematosus

1991 • 113 citations

Pathogenesis of immune complex glomerulonephritis of New Zealand mice.

1971 • 109 citations

PATHOGENESIS OF IMMUNE COMPLEX GLOMERULONEPHRITIS OF NEW ZEALAND MICE

1971 • 101 citations

Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens.

1991 • 90 citations

Functional Reconstitution of Class II MHC-Restricted T Cell Immunity Mediated by Retroviral Transfer of the αβ TCR Complex

2000 • 86 citations

Promiscuous Presentation and Recognition of Nucleosomal Autoepitopes in Lupus: Role of Autoimmune T Cell Receptor α Chain

1998 • 84 citations

Apoptosis and Altered Dendritic Cell Homeostasis in Lupus Nephritis Are Limited by Anti-CD154 Treatment

2001 • 61 citations

MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells

2000 • 56 citations

Antigen-Specific T Cells Transduced with IL-10 Ameliorate Experimentally Induced Arthritis Without Impairing the Systemic Immune Response to the Antigen

2000 • 46 citations

Mixed haplotype A beta Z/A alpha d class II molecule in (NZB x NZW)F1 mice detected by T cell clones.

1993 • 35 citations

MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells

2000 • 9 citations