Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Treatment of B-Cell Lymphoma with Monoclonal Anti-Idiotype Antibody

1982 • 1,001 citations

T Cell Subsets and the Recognition of MHC Class

1983 • 702 citations

Etiopathogenesis of Murine SLE¹

1981 • 517 citations

Use of Monoclonal Antibodies to T-Cell Subsets for Immunologic Monitoring and Treatment in Recipients of Renal Allografts

1981 • 511 citations

The Acquired Immunodeficiency Syndrome

1983 • 474 citations

Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE).

1983 • 453 citations

The Major Histocompatibility Complex of the Mouse

1979 • 423 citations

Serotherapy of a patient with a monoclonal antibody directed against a human lymphoma-associated antigen.

1980 • 413 citations

Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines.

1983 • 377 citations

Immunoregulatory Aberrations in Systemic Lupus Erythematosus

1978 • 359 citations

Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens.

1981 • 338 citations

Serotherapy of acute lymphoblastic leukemia with monoclonal antibody

1981 • 324 citations

Increased Spontaneous Polyclonal Activation of B Lymphocytes in Mice with Spontaneous Autoimmune Disease

1978 • 305 citations

Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice.

1978 • 296 citations

RESPONSE OF CUTANEOUS T CELL LYMPHOMA TO THERAPY WITH HYBRIDOMA MONOCLONAL ANTIBODY

1981 • 265 citations

In vivo effects of murine hybridoma monoclonal antibody in a patient with T-cell leukemia

1981 • 260 citations

Loss of suppressor T cells in adult NZB/NZW mice.

1976 • 229 citations

In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis.

1981 • 228 citations

USE OF ANTI-T-CELL MONOCLONAL ANTIBODY OKT3 TO PREVENT ACUTE GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR ACUTE LEUKAEMIA

1982 • 220 citations

Treatment of (NZB x NZW)F1 disease with anti-I-A monoclonal antibodies.

1983 • 208 citations

Decline in Suppressor T Cell Function with Age in Female NZB Mice

1974 • 206 citations

Familial Abnormalities of Suppressor-Cell Function in Systemic Lupus Erythematosus

1979 • 206 citations

Monoclonal Antibodies

1980 • 189 citations

Treatment of murine lupus with monoclonal anti-T cell antibody.

1985 • 186 citations

Collected Studies on Immunity.

1906 • 184 citations

Demonstration of Activation of B Lymphocytes in New Zealand Black Mice at Birth by an Immunoradiometric Assay for Murine IgM

1977 • 183 citations

Mouse Leukemia: Therapy with Monoclonal Antibodies Against a Thymus Differentiation Antigen

1980 • 183 citations

Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus

1980 • 178 citations

Murine monoclonal antibody therapy in two patients with chronic lymphocytic leukemia

1982 • 168 citations

In vivo therapy with monoclonal anti-I-A antibody suppresses immune responses to acetylcholine receptor

1983 • 165 citations

Effects of monoclonal antibody immunotherapy on patients with gastrointestinal adenocarcinoma.

1984 • 157 citations

Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus

1982 • 155 citations

Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens.

1984 • 140 citations

Collected Studies on Immunity

1907 • 140 citations

BONE MARROW TRANSPLANTATION ACROSS MAJOR HISTOCOMPATIBILITY BARRIERS IN MICE EFFECT OF ELIMINATION OF T CELLS FROM DONOR GRAFTS BY TREATMENT WITH MONOCLONAL THY-1.2 PLUS COMPLEMENT OR ANTIBODY ALONE

1981 • 132 citations

Ability of the xid gene to prevent autoimmunity in (NZB X NZW)F1 mice during the course of their natural history, after polyclonal stimulation, or following immunization with DNA.

1982 • 131 citations

Systemic Lupus Erythematosus: Insights from Animal Models

1984 • 129 citations

Selective Loss of Suppressor Cell Function in New Zealand Mice Induced by NTA

1977 • 121 citations

The effect of thymectomy on lupus-prone mice.

1984 • 116 citations

Tumor therapy with monoclonal antibodies.

1983 • 113 citations

B cell dependence on and response to accessory signals in murine lupus strains.

1983 • 108 citations

Differential Cytotoxic Effect of Natural Thymocytotoxic Autoantibody of NZB Mice on Functional Subsets of T Cells

1978 • 107 citations

Pathogenesis of autoimmunity in New Zealand mice V. Loss of thymic suppressor function

1974 • 86 citations

BONE MARROW TRANSPLANTATION ACROSS MAJOR HISTOCOMPATIBILITY BARRIERS IN MICE

1982 • 77 citations

Treatment of autoimmune MRL/Ipr mice with monoclonal antibody to Thy-1.2: a single injection has sustained effects on lymphoproliferation and renal disease.

1983 • 76 citations

Murine leukaemogenesis: monoclonal antibodies to T-cell determinants arrest T-lymphoma cell proliferation

1980 • 75 citations

Conversion of immunity to suppression by in vivo administration of I-A subregion-specific antibodies.

1982 • 73 citations

Evaluation in primate renal allograft recipients of monoclonal antibody to human T-cell subclasses.

1981 • 68 citations

Monoclonal Antibodies in the Lymphatics: Toward the Diagnosis and Therapy of Tumor Metastases

1982 • 66 citations

In vivo effects of antibodies to immune response gene products. I. Haplotype-specific suppression of humoral immune responses with a monoclonal anti-I-A.

1981 • 60 citations

Total lymphoid irradiation therapy in refractory rheumatoid arthritis

1984 • 60 citations

A sensitive solid phase microradioimmunoassay for anti‐double stranded DNA antibodies

1981 • 50 citations

Changes in T-cell subsets in patients with rheumatoid arthritis treated with total lymphoid irradiation

1983 • 42 citations

Genetic control of lymphocyte suppression. I. Lack of suppression in aged NZB mice is due to a B cell defect.

1978 • 39 citations

Mechanisms of regulation of cell-mediated immunity: Anti-I-A alloantisera interfere with induction and expression of T-cell-mediated immunity to cell-bound antigen in vivo

1980 • 31 citations

Distribution of endothelial-monocyte and HLA antigens on renal vascular endothelium.

1981 • 29 citations

Effect of 89Sr on immunity and autoimmunity in NZB/NZW F1 mice.

1980 • 20 citations

Serotherapy of acute lymphoblastic leukemia with monoclonal antibody

1981 • 14 citations

In vivo effects of murine hybridoma monoclonal antibody in a patient with T-cell leukemia

1981 • 10 citations

Treatment with Anti-Ia and Antiblast/Monocyte Monoclonal Antibodies Can Prolong Skin Allograft Survival in Nonhuman Primates

1982 • 8 citations

Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus. Correlation with clinical features

1982 • 6 citations

Monoclonal antibodies to human T cell subsets: use for immunological monitoring and immunosuppression in renal transplantation.

1982 • 5 citations

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