Regulation of gene expression by prolactin
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References (219)
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Beta-casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary-gland-specific nuclear factor.
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Zinc Mediation of the Binding of Human Growth Hormone to the Human Prolactin Receptor
1990 • 277 citations
Identification of a cDNA Encoding a Long Form of Prolactin Receptor in Human Hepatoma and Breast Cancer Cells
1989 • 274 citations
Prolactin and glucocorticoid hormones synergistically induce expression of transfected rat beta-casein gene promoter constructs in a mammary epithelial cell line.
1989 • 257 citations
Expression of Two Forms of Prolactin Receptor in Rat Ovary and Liver
1990 • 257 citations
Expression of Multiple Forms of the Prolactin Receptor in Mouse Liver
1989 • 237 citations
The 16K Fragment of Prolactin Specifically Inhibits Basal or Fibroblast Growth Factor Stimulated Growth of Capillary Endothelial Cells
1991 • 217 citations
Extracellular matrix and hormones transcriptionally regulate bovine beta-casein 5' sequences in stably transfected mouse mammary cells.
1990 • 217 citations
Anterior pituitary development: Short tales from dwarf mice
1992 • 208 citations
Regulation of interleukin 2-driven T-lymphocyte proliferation by prolactin.
1990 • 194 citations
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3.
1993 • 193 citations
Pregnancy and the Prolactin Family of Hormones: Coordination of Anterior Pituitary, Uterine, and Placental Expression*
1991 • 191 citations
Comparison of long and short forms of the prolactin receptor on prolactin-induced milk protein gene transcription.
1991 • 189 citations
A novel transcriptional enhancer is involved in the prolactin- and extracellular matrix-dependent regulation of beta-casein gene expression.
1992 • 187 citations
Prolactin
1973 • 187 citations
A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor.
1991 • 186 citations
New mammary epithelial and fibroblastic cell clones in coculture form structures competent to differentiate functionally.
1989 • 180 citations
Induction of a Lactogenic Receptor in Rat Liver: Influence of Estrogen and the Pituitary
1974 • 176 citations
Identification and sequence analysis of a second form of prolactin receptor by molecular cloning of complementary DNA from rabbit mammary gland.
1989 • 171 citations
Inducible binding of a factor to the c-fos regulatory region.
1987 • 168 citations
Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells.
1990 • 159 citations
Requirement of Nuclear Prolactin for Interleukin-2—Stimulated Proliferation of T Lymphocytes
1991 • 156 citations
Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds.
1993 • 154 citations
Structural symmetry of the extracellular domain of the Cytokine/Growth hormone/Prolactin receptor family and Interferon receptors revealed by Hydrophobic Cluster Analysis
1991 • 152 citations
Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen.
1988 • 148 citations
Mechanism-based design of prolactin receptor antagonists.
1993 • 143 citations
A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells.
1992 • 143 citations
Prolactin Receptor Gene Expression in Rat Mammary Gland and Liver during Pregnancy and Lactation
1991 • 140 citations
Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion.
1992 • 140 citations
Mammary gland-specific nuclear factor is present in lactating rodent and bovine mammary tissue and composed of a single polypeptide of 89 kDa.
1992 • 137 citations
Prolactin receptor triggering. Evidence for rapid tyrosine kinase activation.
1992 • 137 citations
Human prolactin gene expression. The use of an alternative noncoding exon in decidua and the IM-9-P3 lymphoblast cell line.
1990 • 136 citations
Epidermal Growth Factor Receptor, but Not c-erbB-2, Activation Prevents Lactogenic Hormone Induction of the β-Casein Gene in Mouse Mammary Epithelial Cells
1990 • 129 citations
Prolactin inhibits both thyroid hormone-induced morphogenesis and cell death in cultured amphibian larval tissues
1991 • 125 citations
The differential actions of cortisol on the accumulation of α-lactalbumin and casein in midpregnant mouse mammary gland in culture
1980 • 124 citations
Comparison of the Regulation of the Whey Acidic Protein Gene with that of a Hybrid Gene Containing the Whey Acidic Protein Gene Promoter in Transgenic Mice
1988 • 121 citations
A mammary cell-specific enhancer in mouse mammary tumor virus DNA is composed of multiple regulatory elements including binding sites for CTF/NFI and a novel transcription factor, mammary cell-activating factor.
1992 • 117 citations
Developmental and environmental regulation of a mammary gland-specific nuclear factor essential for transcription of the gene encoding beta-casein.
1992 • 116 citations
Epidermal growth factor receptor, platelet-derived growth factor receptor, and c-erbB-2 receptor activation all promote growth but have distinctive effects upon mouse mammary epithelial cell differentiation.
1991 • 115 citations
Isolation and sequencing of a cDNA clone for a prolactin-inducible protein (PIP). Regulation of PIP gene expression in the human breast cancer cell line, T-47D.
1987 • 115 citations
Interferon gamma rapidly induces in human monocytes a DNA-binding factor that recognizes the gamma response region within the promoter of the gene for the high-affinity Fc gamma receptor.
1992 • 114 citations
An inducible nuclear factor binds to a growth hormone-regulated gene.
1990 • 109 citations
Molecular cloning of the bovine prolactin receptor and distribution of prolactin and growth hormone receptor transcripts in fetal and utero-placental tissues
1992 • 106 citations
Prolactin receptors in human breast cancer cells in long-term tissue culture.
1979 • 104 citations
Changes in prolactin receptor expression during pregnancy in the mouse ovary.
1993 • 103 citations
Evidence for involvement of the growth hormone receptor-associated tyrosine kinase in actions of growth hormone.
1993 • 101 citations
In vitro activation of the transcription factor ISGF3 by interferon alpha involves a membrane-associated tyrosine phosphatase and tyrosine kinase.
1993 • 99 citations
Prolactin stimulates transcription of growth-related genes in Nb2 T lymphoma cells
1990 • 97 citations
The role of growth hormone, prolactin and insulin-like growth factors in the regulation of rat mammary gland and adipose tissue metabolism during lactation
1992 • 96 citations
Prolactin and Glucocorticoid Hormones Control Transcription of the β-Casein Gene by Kinetically Distinct Mechanisms
1990 • 92 citations
Proteins are secreted by both constitutive and regulated secretory pathways in lactating mouse mammary epithelial cells
1992 • 90 citations
TGF beta suppresses casein synthesis in mouse mammary explants and may play a role in controlling milk levels during pregnancy.
1993 • 90 citations
Cloning and characterization of a cDNA encoding a highly conserved, putative calcium binding protein, identified by an anti-prolactin receptor antiserum.
1988 • 89 citations
Detection of prolactin receptor (PRL-R) mRNA in the rat hypothalamus and pituitary gland.
1992 • 86 citations
Requirement for prolactin during cell cycle regulated gene expression in cloned T-lymphocytes.
1992 • 86 citations
Enhancement of Human Growth Hormone-Stimulated Mitogenesis of Nb2Node Lymphoma Cells by 12-O-Tetradecanoyl-Phorbol-13-Acetate*
1985 • 86 citations
Prolactin Receptors in the Rat Hypothalamus: Autoradiographic Localization and Characterization
1993 • 85 citations
The Nb2 form of prolactin receptor is able to activate a milk protein gene promoter.
1992 • 85 citations
Mutational analysis of the ligand-binding domain of the prolactin receptor.
1991 • 84 citations
Both cell substratum regulation and hormonal regulation of milk protein gene expression are exerted primarily at the posttranscriptional level.
1988 • 83 citations
Glycosylation Selectively Alters the Biological Activity of Prolactin*
1988 • 80 citations
Prolactin-inducible proteins in human breast cancer cells.
1985 • 80 citations
Prolactin Influence on Cytosol and Nuclear Androgen Receptors in the Ventral, Dorsal, and Lateral Lobes of the Rat Prostate*
1987 • 79 citations
Prolactin gene expression in human thymocytes
1992 • 77 citations
Dose-dependent effects of human prolactin on the immature hypophysectomized rat testis.
1992 • 77 citations
Gene transfer into somatic tissues by jet injection
1992 • 76 citations
Identification and functional activity of prolactin receptors in thymic epithelial cells.
1991 • 76 citations
Mitogenic and binding properties of monoclonal antibodies to the prolactin receptor in Nb2 rat lymphoma cells. Selective enhancement by anti-mouse IgG.
1990 • 74 citations
Identification of prolactin and growth hormone binding proteins in rabbit milk.
1991 • 74 citations
Cellular and Molecular Biology of Mammary Cancer
1988 • 72 citations
Mammary gland-specific nuclear factor activity is positively regulated by lactogenic hormones and negatively by milk stasis.
1992 • 72 citations
Prolactin stimulation of ornithine decarboxylase and mitogenesis in Nb2 node lymphoma cells: The role of protein kinase C and calcium mobilization
1986 • 71 citations
Epidermal growth factor receptor, but not c-erbB-2, activation prevents lactogenic hormone induction of the beta-casein gene in mouse mammary epithelial cells.
1990 • 71 citations
The prolactin-inducible protein (PIP/GCDFP-15) gene: Cloning, structure and regulation
1991 • 68 citations
Decidual-Type Prolactin Expression by the Human Myometrium
1991 • 68 citations
Transcription of prolactin gene in milk secretory cells of the rat mammary gland
1993 • 67 citations
Comparison of the Roles of Insulin and Insulin-Like Growth Factor I in Casein Gene Expression and in the Development of α-Lactalbumin and Glucose Transport Activities in the Mouse Mammary Epithelial Cell
1987 • 66 citations
Lactogenic Hormone and Cell Type-Specific Control of the Whey Acidic Protein Gene Promoter in Transfected Mouse Cells
1991 • 65 citations
Tumor promoter 12-O-tetradecanoylphorbol 13-acetate, like epidermal growth factor, stimulates cell proliferation and inhibits differentiation of mouse mammary epithelial cells in culture.
1983 • 63 citations
Secretion of insulin-like growth factor-I (IGF-I) and IGF-binding proteins from bovine mammary tissue in vitro
1991 • 63 citations
Prolactin receptor gene expression in lymphoid cells
1991 • 61 citations
Mammary Epithelial Cells of Lactating Rats Express Prolactin Messenger Ribonucleic Acid1
1993 • 61 citations
Multiple forms of prolactin receptor messenger ribonucleic acid are specifically expressed and regulated in murine tissues and the mammary cell line HC11.
1992 • 61 citations
A dual role of growth hormone as a feminizing and masculinizing factor in the control of sex-specific cytochrome P-450 isozymes in rat liver
1989 • 60 citations
Servomechanism of Prolactin and Progesterone in Regulating Uterine
1988 • 59 citations
Evidence for a rapid stimulation of tyrosine kinase activity by prolactin in Nb2 rat lymphoma cells.
1992 • 59 citations
Prolactin stimulates milk protein promoter in CHO cells cotransfected with prolactin receptor cDNA
1990 • 58 citations
Isolation and characterization of two novel rat ovarian lactogen receptor cDNA species
1990 • 57 citations
Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin.
1992 • 57 citations
Crystals of the complex between human growth hormone and the extracellular domain of its receptor
1991 • 56 citations
The mammary gland as a bioreactor: Production of foreign proteins in milk
1990 • 56 citations
Transfection of beta-casein chimeric gene and hormonal induction of its expression in primary murine mammary epithelial cells.
1990 • 55 citations
Overexpression of Mos, Ras, Src, and Fos inhibits mouse mammary epithelial cell differentiation.
1992 • 54 citations
Delayed secondary glucocorticoid response elements. Unusual nucleotide motifs specify glucocorticoid receptor binding to transcribed regions of alpha 2u-globulin DNA.
1991 • 53 citations
Prolactin and fetal osmoregulation: water transport across isolated human amnion
1977 • 53 citations
Multihormonal Regulation of Milk Protein Gene Expression
1986 • 52 citations
Precocious Mammary Gland Development and Milk Protein Synthesis in Transgenic Mice Ubiquitously Expressing Human Growth Hormone*
1991 • 52 citations
Multiple Regulation of Prolactin Receptor Gene Expression in Rat Liver
1989 • 52 citations
Glucocorticoid receptor binding sites in the promoter region of milk protein genes
1993 • 52 citations
Ontogeny of messenger RNA for the rat growth hormone receptor and serum binding protein
1992 • 51 citations
Prolactin Stimulates the Expression of Luteinizing Hormone/Chorionic Gonadotropin Receptor Messenger Ribonucleic Acid in the Rat Corpus Luteum and Rescues Early Pregnancy from Bromocriptin-Induced Abortion1
1992 • 50 citations
A pregnancy-specific mammary nuclear factor involved in the repression of the mouse beta-casein gene transcription by progesterone.
1992 • 49 citations
Role of protein kinase C in the prolactin-induced responses in mouse mammary gland explants
1989 • 49 citations
Growth hormone- and prolactin-binding proteins in mammalian serum.
1992 • 48 citations
Studies of muc-1 mucin expression and polarity in the mouse mammary gland demonstrate developmental regulation of muc-1 glycosylation and establish the hormonal basis for mrna expression
1992 • 48 citations
Role of Calcium in Prolactin-Stimulated c-mycGene Expression and Mitogenesis in NB2 Lymphoma Cells*
1988 • 48 citations
Ha-ras and v-raf oncogenes, but not int-2 and c-myc, interfere with the lactogenic hormone dependent activation of the mammary gland specific transcription factor.
1993 • 47 citations
Transforming Growth Factor-β Inhibits Lactogenic Hormone Induction of β-Casein Expression in HC11 Mouse Mammary Epithelial Cells
1990 • 46 citations
Mechanisms of prolactin receptor regulation in mammary gland
1993 • 46 citations
A Sex-Specific Endogenous Stimulatory Rhythm Regulating Prolactin Secretion*
1989 • 45 citations
A mouse mammary tumor virus mammary gland enhancer confers tissue-specific but not lactation-dependent expression in transgenic mice
1992 • 45 citations
Prolactin receptor gene expression in the rabbit: Identification, characterization and tissue distribution of several prolactin receptor messenger RNAs encoding a unique precursor
1991 • 43 citations
Regulation of 70-Kilodalton Heat-Shock-Like Messenger Ribonucleic Acidin Vitroandin Vivoby Prolactin
1987 • 42 citations
Prolactin as an immunoregulatory hormone in mammals and birds
1992 • 42 citations
Regulation of α2-Macroglobulin by Luteinizing Hormone and Prolactin during Cell Differentiation in the Rat Ovary
1991 • 42 citations
Prognostic significance of prolactin receptors in human breast cancer.
1987 • 41 citations
Interferon regulatory factor-1 is inducible by prolactin, interleukin-2 and concanavalin A in T cells
1992 • 41 citations
Induction of the endogenous whey acidic protein (Wap) gene and a Wap-myc hybrid gene in primary murine mammary organoids
1990 • 40 citations
Growth-hormone-prolactin interactions in the regulation of mammary and adipose-tissue acetyl-CoA carboxylase activity and gene expression in lactating rats
1992 • 40 citations
Characterization of prolactin receptor in human brain and choroid plexus
1992 • 39 citations
Prolactin enhances uteroglobin gene expression by uteri of immature rabbits
1991 • 39 citations
Hormone responsive elements within the upstream sequences of the rabbit whey acidic protein (WAP) gene direct chloramphenicol acetyl transferase (CAT) reporter gene expression in transfected rabbit mammary cells
1991 • 38 citations
A placenta-specific 5 ' non-coding exon of human prolactin
1991 • 37 citations
Prolactin augments progesterone-dependent uteroglobin gene expression by modulating promoter-binding proteins.
1993 • 37 citations
The transcription factor interferon regulatory factor-1 is expressed during both early G1 and the G1/S transition in the prolactin-induced lymphocyte cell cycle.
1992 • 37 citations
Mammary epithelial differentiation in vitro: minimum requirements for a functional response to hormonal stimulation.
1991 • 36 citations
Purification of a distinct placental lactogen receptor, a new member of the growth hormone/prolactin receptor family.
1989 • 36 citations
Mouse cDNAs encoding a trifunctional protein of de novo purine synthesis and a related single-domain glycinamide ribonucleotide synthetase
1993 • 35 citations
Lactogenic Hormones Stimulate the Liver to Secrete a Factor that Acts Synergistically with Prolactin to Promote Growth of the Pigeon Crop-Sac Mucosal Epitheliumin Vivo*
1985 • 35 citations
Lactogenic hormones increase epidermal growth factor messenger RNA content of mouse mammary glands
1991 • 34 citations
Prolactin-induced protein kinase C activity in a mouse mammary cell line (NOG-8)
1992 • 34 citations
Involvement of physiological prolactin levels in growth and prolactin receptor content of prostate glands and testes in developing male rats
1992 • 33 citations
V-MycAlters the Response of a Cloned Mouse Mammary Epithelial Cell Line to Lactogenic Hormones
1988 • 32 citations
Expression of a lactogen-dependent insulin-like growth factor-binding protein in cultured mouse mammary epithelial cells.
1992 • 32 citations
Regulation of expression of genes for milk proteins.
1991 • 32 citations
Isolation and biochemical properties of four forms of glycosylated porcine prolactin
1991 • 31 citations
Hormonal Induction of β-Casein Gene Expression: Requirement of Ongoing Protein Synthesis for Transcription
1990 • 31 citations
Multiple and differential regulation of ovarian prolactin receptor messenger RNAs and their expression
1991 • 28 citations
Cortisol induces rapid accumulation of whey acid protein mRNA but not of as1 and b-casein mRNA in rabbit mammary explants
1991 • 27 citations
Androgen regulation of prolactin‐receptor gene expression in MCF‐7 and MDA‐MB‐453 human breast cancer cells
1992 • 27 citations
Interaction of lactogenic hormones with purified recombinant extracellular domain of rabbit prolactin receptor expressed in insect cells
1993 • 27 citations
A marsupial β-lactoglobulin gene: characterization and prolactin-dependent expression
1991 • 27 citations
Transcriptional Analysis of the Mouse β-Casein Gene
1990 • 26 citations
Regulation of Expression of the Messenger Ribonucleic Acid Encoding the Cytosolic Form of Phosphoenolpyruvate Carboxykinase in Liver and Small Intestine of Lactating Rats*
1989 • 26 citations
Annexin-I Regulation in Response to Suckling and Rat Mammary Cell Differentiation*
1991 • 26 citations
Prolactin Increases Cytosolic Free Calcium Concentration in Hepatocytes of Lactating Rats*
1991 • 26 citations
Prolactin receptor does not correlate with oestrogen and progesterone receptors in primary breast cancer and lacks prognostic significance. Ten year results of the Naples adjuvant (GUN) study
1990 • 26 citations
Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma
1992 • 25 citations
A Complex Noncoordinate Regulation ofα-Lactalbumin and 25 Kβ-Casein by Corticosterone, Prolactin, and Insulin in Long Term Cultures of Normal Rat Mammary Cells*
1986 • 25 citations
Gene expression in the mammary gland
1990 • 25 citations
Cross-linking of G-proteins to the prolactin receptor in rat NB2 lymphoma cells
1990 • 24 citations
Prolactin Effects and Regulation of its Receptors in Human Mammary Tumor Cells
1987 • 24 citations
Structure of the gene encoding columbid annexin Icp35
1991 • 24 citations
A Mutant Lactogenic Hormone Binds, but Does not Activate, the Prolactin Receptor
1989 • 23 citations
Human breast cancer: Concerted role of diet, prolactin and adrenal C19‐Δ5‐steroids in tumorigenesis
1992 • 23 citations
Progesterone regulation of a pregnancy-specific transcription repressor to beta-casein gene promoter in mouse mammary gland.
1992 • 22 citations
Prolactin stimulation of protein kinase C activity in the rat hypothalamus
1991 • 22 citations
Prolactin stimulates transcription of aspartate aminotransferase in prostate cells
1992 • 21 citations
Role of GTPases and GTPase regulatory proteins in oncogenesis.
1993 • 21 citations
Analysis of disuiphide bridge function in recombinant bovine prolactin using site-specific mutagenesis and renaturation under mild alkaline conditions: a crucial role for the central disuiphide bridge in the mitogenic activity of the hormone
1992 • 20 citations
Effect of various protein kinase inhibitors on the induction of milk protein gene expression by prolactin
1993 • 20 citations
Prolactin receptor expression by lymphoid tissues in normal and immunized rats
1993 • 20 citations
Expression of the full-length rabbit prolactin receptor and its specific domains in baculovirus infected insect cells
1992 • 19 citations
DNA-binding proteins and their cis-acting sites controlling hormonal induction of a mouse β-casein::CAT fusion protein in mammary epithelial cells
1993 • 19 citations
Effect of a tyrosine kinase inhibitor, genistein, on the actions of prolactin in cultured mouse mammary tissues
1992 • 19 citations
Molecular cloning and characterization of a novel marsupial milk protein gene
1989 • 19 citations
Human prolactin regulates transfected MMTV LTR‐directed gene expression in a human breast‐carcinoma cell line through synergistic interaction with steroid hormones
1992 • 18 citations
Monoclonal antibodies against human, bovine and rat prolactin: epitope mapping of human prolactin and development of a two-site immunoradiometric assay
1987 • 18 citations
Factors affecting protein composition of breast secretions from nonlactating women
1992 • 17 citations
A distal region enhances the prolactin induced promoter activity of the rabbit αs1-casein gene
1992 • 16 citations
Mechanisms Whereby Prolactin Modulates Lipogenesis in Sheep Mammary Gland
1991 • 16 citations
Prolactin-induced proliferation of the Nb2 T-lymphoma is associated with protein kinase-C-independent phosphorylation of stathmin.
1992 • 15 citations
Effect of prolactin on 2-deoxyglucose uptake in mouse mammary gland explants
1992 • 15 citations
Temporal Effect of Prolactin on the Activities of Lactose Synthetase, -Lactalbumin, and Galactosyl Transferase in Mouse Mammary Gland Explants
1991 • 14 citations
Inhibition of casein synthesis by progestagens In vitro: Modulation in relation to concentration of hormones that synergize with prolactin
1989 • 14 citations
Nuclear proteins and prolactin-induced annexin Icp35 gene transcription.
1992 • 14 citations
Mammary Gland Differentiation in Hypophysectomized, Pregnant Mice Treated with Corticosterone and Thyroxine1
1992 • 12 citations
Absence of a putative ATPGTP binding site in the rat prolactin receptor
1992 • 12 citations
Prolactin and total lactogenic hormone measured by microbioassay and immunoassay in breast cancer
1992 • 12 citations
Posttranscriptional regulation of α-casein mRNA accumulation by laminin
1992 • 12 citations
Studies on the mechanism by which prolactin regulates protein, RNA, and DNA synthesis in Nb2 node lymphoma cells
1989 • 11 citations
Autocrine Stimulation of Nb2 Cell Proliferation by Secreted, but not Intracellular, Prolactin
1988 • 9 citations
Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12‐O‐tetradecanoylphorbol‐13‐acetate in human breast cancer cells
1993 • 9 citations
Differential effects of the simian virus 40 early genes on mammary epithelial cell growth, morphology, and gene expression
1992 • 8 citations
Structure of growth hormone and its receptor: an unexpected stoichiometry
1992 • 7 citations
Progesterone and prolactin are both required for suppression of the induction of rat α-lactalbumin activity
1988 • 6 citations
Epitope mapping of monoclonal antibodies to bovine prolactin
1992 • 6 citations
High tumour prolactin receptor content and lack of increase in serum prolactin levels as predictors of good response to endocrine therapy in rat mammary cancer
1988 • 4 citations
Prolactin and Progesterone Receptors in Pregnancy-Dependent Mammary Tumors in GR/A Mice
1990 • 4 citations
Vergleichende Untersuchungen zum Prolaktin-, Östrogen-, Gestagen und Androgenrezeptorgehalt menschlicher Mammakarzinome
1988 • 3 citations