Prolactin stimulation of ornithine decarboxylase and mitogenesis in Nb2 node lymphoma cells: The role of protein kinase C and calcium mobilization

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Statistical methods in medical research

1972 • 1,303 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

1985 • 753 citations

Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors.

1968 • 742 citations

A New Sensitive and Specific Bioassay for Lactogenic Hormones: Measurement of Prolactin and Growth Hormone in Human Serum*

1980 • 574 citations

Cyclic 3',5'-Nucleotide Phosphodiesterase

1971 • 531 citations

A Randomized Clinical Trial of Cyclosporine in Cadaveric Renal Transplantation

1983 • 467 citations

Inhibition of protein kinase C by tamoxifen.

1985 • 464 citations

Prolactin receptors on human T and B lymphocytes: antagonism of prolactin binding by cyclosporine.

1985 • 356 citations

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1978 • 355 citations

Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.

1985 • 351 citations

Voltage-gated potassium channels are required for human T lymphocyte activation.

1984 • 337 citations

Synergistic functions of phorbol ester and calcium in serotonin release from human platelets

1983 • 335 citations

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.

1985 • 332 citations

Tamoxifen is a calmodulin antagonist in the activation of cAMP phosphodiesterase

1984 • 296 citations

Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.

1982 • 282 citations

Prolactin-stimulated growth of cell cultures established from malignant Nb rat lymphomas.

1980 • 279 citations

Inositol phospholipids in membrane function

1979 • 272 citations

R 24571: A new powerful inhibitor of red blood cell Ca++-transport ATPase and of calmodulin-regulated functions

1981 • 260 citations

Growth factor activation of an amiloride-sensitive Na+/H+ exchange system in quiescent fibroblasts: coupling to ribosomal protein S6 phosphorylation.

1982 • 240 citations

Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.

1982 • 218 citations

IMMUNODEFICIENCY IN HYPOPHYSECTOMIZED RATS

1978 • 196 citations

Specificity of the Fatty Acyl Moieties of Diacylglycerol for the Activation of Calcium-Activated, Phospholipid-Dependent Protein Kinase1

1982 • 182 citations

Hormonal induction of the secretory immune system in the mammary gland.

1978 • 175 citations

Prolactin receptors on human lymphocytes and their modulation by cyclosporine

1984 • 157 citations

Amiloride directly inhibits growth factor receptor tyrosine kinase activity.

1985 • 155 citations

Prolactin and Growth Hormone Production as Influenced by Catecholamines and Agents that Affect Brain Catecholamines

1970 • 152 citations

Receptor-Mediated Mitogenic Action of Prolactin in a Rat Lymphoma Cell Line^*

1983 • 152 citations

Synergistic action of phorbol esters in mitogen-activated bovine lymphocytes

1974 • 145 citations

Phorbol Esters Stimulate Growth and Inhibit Differentiation in Cultured Thyroid Cells*

1985 • 142 citations

Structure-activity relationships in diterpene esters irritant and cocarcinogenic to mouse skin

1978 • 137 citations

Calcium‐dependent activation of lymphocytes by ionophore, A23187, and a phorbol ester tumor promoter

1983 • 120 citations

Cyclic AMP levels in synchronized mammalian cells

1972 • 102 citations

Cobra polypeptide cytotoxin I and marine worm polypeptide cytotoxin A‐IV are potent and selective inhibitors of phospholipid‐sensitive Ca²⁺‐dependent protein kinase

1983 • 100 citations

Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding.

1985 • 94 citations

Structural and chemical specificity of diradylglycerols for protein kinase C activation

1984 • 92 citations

Enhancement of Human Growth Hormone-Stimulated Mitogenesis of Nb₂Node Lymphoma Cells by 12-O-Tetradecanoyl-Phorbol-13-Acetate*

1985 • 86 citations

Rapid phosphorylation-dephosphorylation of specific proteins induced by phorbol ester in HL-60 cells. Further characterization of the phosphorylation of 17-kilodalton and 27-kilodalton proteins in myeloid leukemic cells and human monocytes.

1984 • 78 citations

Cyclosporine inhibits prolactin induction of ornithine decarboxylase in rat tissues

1984 • 77 citations

Tumor-promoting phorbol esters stimulate the phosphorylation of ribosomal protein S6 in quiescent Reuber H35 hepatoma cells.

1984 • 75 citations

Receptors and calcium signalling

1980 • 73 citations

Alterations in polyamine levels induced by phorbol diesters and other agents that promote differentiation in human promyelocytic leukemia cells

1981 • 69 citations

Cyclic AMP dependent regulation of mitosis in human lymphoid cells

1974 • 67 citations

Prolactin is a tumor promoter in rat liver

1985 • 66 citations

Electroimmunology: the physiologic role of ion channels in the immune system

1985 • 53 citations

Induction of ornithine decarboxylase in guinea‐pig lymphocytes

1985 • 49 citations

Biochemical response of lymphoma cells to mitogenic stimulation by prolactin

1982 • 47 citations

Intracellular calcium and skin tumor promotion: Calcium regulation of the induction of epidermal ornithine decarboxylase activity by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate

1981 • 46 citations

Prolactin-induced polyamine biosynthesis in spleen and thymus: Specific inhibition by cyclosporine

1985 • 36 citations

Suppression of lectin-stimulated DNA synthesis in bovine lymphocytes by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.

1980 • 32 citations

Effect of macrophages on phorbol ester-stimulated comitogenesis in bovine lymphocytes.

1982 • 23 citations

Rapid elevation of plasminogen activator activity in rat tissues by prolactin

1984 • 22 citations

Antagonism of concanavalin A capping in phorbol ester-activated lymphocytes by calmodulin inhibitors and certain amino acid esters.

1982 • 21 citations

Prolactin Stimulation of Ornithine Decarboxylase Activity in the Mammary Gland May Involve an Activation of Protein Kinase C

1985 • 17 citations

In vivo induction of rat hepatic ornithine decarboxylase and plasminogen activator by 12-O-tetradecanoypphorbol 13-acetate

1985 • 16 citations

Methods in Ethology: Quantitative Ethology . Patrick W. Colgan, Ed. Wiley-Interscience, New York, 1978. xvi, 364 pp., illus. $25.

1978 • 2 citations