Precocious Mammary Gland Development and Milk Protein Synthesis in Transgenic Mice Ubiquitously Expressing Human Growth Hormone*

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes

1982 • 1,338 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Somatomedin: Proposed Designation for Sulphation Factor

1972 • 840 citations

Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family

1988 • 564 citations

Growth Enhancement of Transgenic Mice Expressing Human Insulin-Like Growth Factor I*

1988 • 481 citations

Human growth hormone DNA sequence and mRNA structure: possible alternative splicing

1981 • 464 citations

Mammary ductal elongation: Differentiation of myoepithelium and basal lamina during branching morphogenesis

1983 • 453 citations

Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring

1982 • 379 citations

Organ specificity in mesenchymal induction demonstrated in the embryonic development of the mammary gland of the mouse

1969 • 327 citations

Complex hormonal regulation of rat casein gene expression.

1982 • 204 citations

Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription.

1988 • 196 citations

Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene

1984 • 187 citations

Expression of Insulin-Like Growth Factor I in Transgenic Mice with Elevated Levels of Growth Hormone Is Correlated with Growth*

1988 • 182 citations

Comparison of the whey acidic protein genra of the rat and mouse

1984 • 176 citations

Studies of GH Secretion in Mice by a Homologous Radioimmunoassay for Mouse GH1

1972 • 140 citations

Plasmid and bacteriophage vectors for excision of intact inserts

1987 • 127 citations

Comparison of the Regulation of the Whey Acidic Protein Gene with that of a Hybrid Gene Containing the Whey Acidic Protein Gene Promoter in Transgenic Mice

1988 • 121 citations

Spermidine as a Possible Mediator of Glucocorticoid Effect on Milk Protein Synthesis in Mouse Mammary Epithelium in Vitro

1974 • 119 citations

NON-LACTOGENIC EFFECTS OF GROWTH HORMONE ON GROWTH AND INSULIN-LIKE GROWTH FACTOR-I MESSENGER RIBONUCLEIC ACID OF RAT MAMMARY GLAND

1990 • 105 citations

Hormonal Regulation of Milk Protein Gene Expression

1989 • 100 citations

On the prenatal growth of the mammary gland rudiment in the mouse.

1950 • 97 citations

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice.

1988 • 87 citations

The Ontogeny of Mouse Mammary Gland Responsiveness to Ovarian Steroid Hormones*

1989 • 83 citations

A ubiquitous mammalian expression vector, pHMG, based on a housekeeping gene promoter

1989 • 81 citations

Studies on the expression of an H-2K/human growth hormone fusion gene in giant transgenic mice.

1986 • 74 citations

Plasma Gonadotropins in Prenatal and Prepubertal Female Mice: Disorganization of Pubertal Cycles in the Absence of a Male¹

1974 • 62 citations

Hormone-inducible casein messenger RNA in a serum-free organ culture of whole mammary gland

1977 • 57 citations

Fetal mammary gland differentiation in vitro in response to hormones

1970 • 55 citations

Serum Placental Lactogen in Mice in Relation to Day of Gestation and Number of Conceptuses

1981 • 50 citations

Characterization of the Change in Type I and II Insulin-Like Growth Factor Receptors of Bovine Mammary Tissue during the Pre- and Postpartum Periods*

1990 • 43 citations

Molecular Size Variants of Prolactin and Growth Hormone in Mouse Serum: Strain Differences and Alterations of Concentrations by Physiological and Pharmacological Stimuli*

1980 • 29 citations

EXPERIMENTAL INDUCTION OF MAMMOGENESIS AND LACTOGENESIS IN THE DWARF MOUSE

1961 • 6 citations