CD95/CD95L-mediated apoptosis of the hepatic stellate cell. A mechanism terminating uncontrolled hepatic stellate cell proliferation during hepatic tissue repair.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1995 • 5,208 citations

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

1997 • 4,921 citations

p21 is a universal inhibitor of cyclin kinases

1993 • 3,408 citations

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

1994 • 2,141 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1997 • 1,768 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1994 • 1,073 citations

Lymphocyte apoptosis induced by CD95 (APO–1/Fas) ligand–expressing tumor cells — A mechanism of immune evasion?

1996 • 917 citations

FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis

1996 • 780 citations

An evolutionary perspective on apoptosis

1994 • 758 citations

Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.

1994 • 697 citations

Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

1990 • 654 citations

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

1993 • 643 citations

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

1992 • 605 citations

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1995 • 546 citations

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

1995 • 470 citations

Cell death by apoptosis and its protective role against disease

1992 • 439 citations

Immunocytochemical Detection of Desmin in Fat-Storing Cells (Ito Cells)

1984 • 393 citations

Purified Rat Liver Fat-Storing Cells in Culture Divide and Contain Collagen

1984 • 326 citations

Regulation of apoptosis in the immune system

1994 • 321 citations

Expression of the gene of the α-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells

1990 • 283 citations

Isolation and characterization of Kupffer and endothelial cells from the rat liver

1977 • 246 citations

Hemorrhage in lesions caused by cowpox virus is induced by a viral protein that is related to plasma protein inhibitors of serine proteases.

1986 • 207 citations

Glial fibrillary acidic protein - a cell type specific marker for Ito cells in vivo and in vitro

1996 • 177 citations

The Bcl-2 Oncoprotein Functions as a Pro-oxidant

1995 • 156 citations

Accumulation and cellular localization of fibrinogen/fibrin during shortterm and longterm rat liver injury

1995 • 125 citations

Multiple pathways to apoptosis.

1993 • 113 citations

Characterization of desmin-positive rat liver sinusoidal cells

1987 • 111 citations

Fat storing cells (FSC) of rat liver synthesize and secrete fibronectin

1987 • 95 citations

The EBV-encoded LMP1 protein inhibits p53-triggered apoptosis but not growth arrest.

1995 • 82 citations

Induction of rat liver parenchymal cell apoptosis by hepatic myofibroblasts via transforming growth factor ?

1996 • 68 citations

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1995 • 8 citations