T-Cell Immune Reconstitution in Pediatric Leukemia Patients After Allogeneic Bone Marrow Transplantation With T-Cell–Depleted or Unmanipulated Grafts: Evaluation of Overall and Antigen-Specific T-Cell Repertoires

Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy

1995 • 1,066 citations

Immunophenotyping of blood lymphocytes in childhoodReference values for lymphocyte subpopulations

1997 • 733 citations

Human T-cell receptor variable gene segment families

1995 • 663 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Allogeneic Bone‐Marrow Transplantation

1983 • 614 citations

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.

1994 • 539 citations

Large clonal expansions of CD8+ T cells in acute infectious mononucleosis

1996 • 478 citations

Structure, Organization and Polymorphism of Murine and Human T‐Cell Receptor a and β Chain Gene Families

1988 • 448 citations

Age-related changes in human blood lymphocyte subpopulations

1992 • 446 citations

The kinetics of immune reconstitution after human marrow transplantation

1987 • 428 citations

Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

1996 • 418 citations

Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain.

1985 • 416 citations

Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II–expressing Dendritic Cells

1997 • 402 citations

Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping: correlation with immune status

1995 • 400 citations

Distinctions Between CD8+ and CD4+ T-Cell Regenerative Pathways Result in Prolonged T-Cell Subset Imbalance After Intensive Chemotherapy

1997 • 388 citations

Optimal conditions for directly sequencing double-stranded PCR products with Sequenase

1990 • 357 citations

Thymic involution with ageing: obsolescence or good housekeeping?

1996 • 351 citations

Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. Correlation with immune status.

1994 • 345 citations

Expanded CD4+ and CD8+ T cell clones in elderly humans.

1997 • 307 citations

Diversity of the Immunoglobulin Gene Superfamily

1989 • 293 citations

Does graft-versus-host disease influence the tempo of immunologic recovery after allogeneic human marrow transplantation? An observation on 56 long-term survivors

1978 • 266 citations

Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

1989 • 261 citations

T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life.

1995 • 259 citations

T-cell regeneration: all repertoires are not created equal

1997 • 246 citations

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

1994 • 232 citations

Analysis of T-cell repopulation after allogeneic bone marrow transplantation: significant differences between recipients of T-cell depleted and unmanipulated grafts

1996 • 231 citations

Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts

1997 • 230 citations

Reconstitution of the T-Cell Compartment After Bone Marrow Transplantation: Restoration of the Repertoire by Thymic Emigrants

1998 • 223 citations

Essential Role of the Thymus to Reconstitute Naive (CD45RA+) T-Helper Cells After Human Allogeneic Bone Marrow Transplantation

1997 • 204 citations

Unexpectedly Complex Regulation of CD4/CD8 Coreceptor Expression Supports a Revised Model for CD4+CD8+ Thymocyte Differentiation

1996 • 199 citations

Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium

1995 • 196 citations

Immunological reconstitution following bone marrow transplantation

1997 • 187 citations

Thymic selection: a matter of life and death

1992 • 184 citations

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology

1993 • 181 citations

The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8⁺ T cell pools

1995 • 174 citations

Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells.

1991 • 173 citations

In Thymic Selection, Peptide Diversity Gives and Takes Away

1997 • 136 citations

Differential usage of T cell receptor V gene segments in CD4+ and CD8+ subsets of T lymphocytes in monozygotic twins.

1993 • 124 citations

T-cell repertoires in healthy and diseased human tissues analysed by T-cell receptor β-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases

1995 • 117 citations

Both CD45RA+ and CD45RA- subpopulations of CD8+ T cells contain cells with high levels of lymphocyte function-associated antigen-1 expression, a phenotype of primed T cells.

1993 • 112 citations

The organization of mature T-cell pools

1998 • 108 citations

Oligoclonality of CD8 + T cells in health and disease: Aging, infection, or immune regulation?

1996 • 107 citations

Age‐related accumulation of LFA‐1^high cells in a CD8⁺CD45RA^high T cell population

1993 • 101 citations

Phenotype of lymphocyte subsets after autologous peripheral blood stem cell transplantation

1997 • 100 citations

Biased expression of individual T cell receptor V gene segments in CD4⁺ and CD8⁺ human peripheral blood T lymphocytes

1991 • 98 citations

Development of Epstein-Barr virus-specific memory T cell receptor clonotypes in acute infectious mononucleosis.

1996 • 87 citations

A Class I MHC-Restricted Recall Response to a Viral Peptide Is Highly Polyclonal Despite Stringent CDR3 Selection: Implications for Establishing Memory T Cell Repertoires in “Real-World” Conditions

1998 • 87 citations

Pathology of the thymus after allogeneic bone marrow transplantation in man. A histologic immunohistochemical study of 36 patients.

1987 • 81 citations

RAG1, RAG2 and pre‐T cell receptor α chain expression by adult human hepatic T cells: evidence for extrathymic T cell maturation

1996 • 76 citations

Immune reconstitution after BMT in children.

1993 • 73 citations

Thymic selection of the human T cell receptor V beta repertoire in SCID-hu mice.

1992 • 70 citations

Phenotypic and functional reconstitution of peripheral blood lymphocytes following T cell-depleted bone marrow transplantation from partially mismatched related donors

1998 • 70 citations

Stable clonal expansion of T cells induced by bone marrow transplantation

1996 • 70 citations

Molecular and cell biological studies of ageing and their application to considerations of T lymphocyte immunosenescence

1995 • 63 citations

PATTERN OF T CELL RECONSTITUTION FOLLOWING ALLOGENEIC BONE MARROW TRANSPLANTATION FOR ACUTE HEMATOLOGICAL MALIGNANCY

1982 • 62 citations

Different TCRBV genes generate biased patterns of V-D-J diversity in human T cells

1995 • 58 citations

T-cell repertoire complexity after allogeneic bone marrow transplantation

1996 • 53 citations

Experimental Haematology Today

1980 • 52 citations

Effect of cyclosporin A on lymphopoiesis. II. Developmental defects of immature and mature thymocytes in fetal thymus organ cultures treated with cyclosporin A.

1989 • 50 citations

Dynamic changes of accumulated T cell clonotypes during antigenic stimulation in vivo and in vitro

1994 • 49 citations

Non-random employment of Vβ6 and Jβ gene elements and conserved amino acid usage profiles in CDR3 regions of human fetal and adult TCR β chain rearrangements

1994 • 45 citations

Clonal dysregulation of the antibody response to tetanus-toxoid after bone marrow transplantation

1994 • 40 citations

Analysis of Jβ gene segment usage by CD4⁺ and CD8⁺ human peripheral blood T lymphocytes

1992 • 38 citations

T cell receptor clonal diversity following allogeneic marrow grafting

1996 • 37 citations

Assessment of T-Cell receptor β-chain diversity by heteroduplex analysis

1996 • 31 citations

Simultaneous detection of X and Y chromosomes by two-colour fluorescence in situ hybridization in combination with immunophenotyping of single cells to document chimaerism after sex-mismatched bone marrow transplantation

1998 • 29 citations

Modified MHC restriction of donor-origin T cells in humans with severe combined immunodeficiency transplanted with haploidentical bone marrow stem cells.

1989 • 28 citations

In VivoLongitudinal Analysis of a Dominant TCR Repertoire Selected in Human Response to Influenza Virus

1997 • 28 citations

Incomplete T-Cell Immune Reconstitution in Two Major Histocompatibility Complex Class II–Deficiency/Bare Lymphocyte Syndrome Patients After HLA-Identical Sibling Bone Marrow Transplantation

1999 • 26 citations

Properties of transcription factors regulating interleukin-2 gene transcription through the NFAT binding site in untreated or drug- treated naive and memory T-helper cells

1994 • 24 citations

Abnormal distribution of T cell subsets in the thymus of cyclosporin A (CsA)-treated mice.

1988 • 16 citations

Lymphocyte reconstitution in children receiving soybean agglutinin T-depleted bone marrow transplants.

1987 • 9 citations

Long-Term T Cell Immune Reconstitution in 2 SCID Patients After BMT

1998 • 9 citations

Immunophenotyping of lymphocytes in healthy and immunodeficient children

1999 • 6 citations

PROLONGATION OF CARDIAC ALLOGRAFT SURVIVAL IN RATS BY COMBINED PRETRANSPLANT THYMECTOMY, SPLENECTOMY, AND ANTILYMPHOCYTE GLOBULIN TREATMENT

1982 • 4 citations