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Age‐related accumulation of LFA‐1high cells in a CD8+CD45RAhigh T cell population

Data up to Jan 2025

Published1993
Citations101
References35

Total Citations Per Year

Abstract

References (35)

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

Interconversion of CD45R subsets of CD4 T cells in vivo

1990 • 371 citations

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

1987 • 327 citations

Pgp‐1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A

1989 • 279 citations

Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice.

1990 • 264 citations

Structural variants of human T200 glycoprotein (leukocyte-common antigen).

1987 • 239 citations

Age-related changes in human lymphocyte subsets: Progressive reduction of the CD4 CD45R (suppressor inducer) population

1988 • 220 citations

Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.

1988 • 218 citations

The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation.

1988 • 213 citations

Cyclic regulation of CD45 isoform expression in a long term human CD4+CD45RA+ T cell line.

1991 • 186 citations

Activation signals regulate heat shock transcription factor 1 in human B lymphocytes

1997 • 169 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.

1985 • 145 citations

Evidence for differential expression of CD45 isoforms by precursors for memory-dependent and independent cytotoxic responses: human CD8 memory CTLp selectively express CD45R0 (UCHL1)

1989 • 138 citations

Human CD8+ T lymphocytes can be divided into CD45RA+ and CD45RO+ cells with different requirements for activation and differentiation.

1991 • 118 citations

Ontogeny of expression of UCHL1 antigen on TcR‐1+ (CD4/8) and TcRδ+ T cells

1989 • 112 citations

Phenotypic identification of memory cytolytic T lymphocytes in a subset of Lyt-2+ cells.

1987 • 110 citations

CD45 isoform expression during T cell development in the thymus

1992 • 87 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. I. Ontogeny of antigen expression.

1985 • 84 citations

Sequences of Ly-5 cDNA: isoform-related diversity of Ly-5 mRNA.

1986 • 74 citations

Loss of activation-induced CD45RO with maintenance of CD45RA expression during prolonged culture of T cells and NK cells.

1991 • 73 citations

Cellular events during memory T-cell activation in vitro: the UCHL1 (180,000 MW) determinant is newly synthesized after mitosis.

1989 • 57 citations

Basal Synthesis of Heat Shock Protein 70 Increases with Age in Rat Kidneys

1997 • 53 citations

Identification and isolation of OKT4+ suppressor cells with the monoclonal antibody WR16.

1986 • 43 citations

Age-related changes in naive and memory CD4+ T cells in healthy human children

1989 • 43 citations

Reversal of CD45R isoform switching in CD8+ T cells

1992 • 39 citations

Development of lymphocyte subsets in pigtailed macaques

1988 • 25 citations

Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM)-P/8 and SAM-R/1 substrains

1992 • 24 citations

Suppression associated lymphocyte markers in lesions of sarcoidosis.

1988 • 17 citations

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Age‐related accumulation of LFA‐1high cells in a CD8+CD45RAhigh T cell population (1993) – European Journal of Immunology | Metascience Observatory Explorer