The palmitoylation status of the G-protein Go1 α regulates its activity of interaction with the plasma membrane

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Posttranslational modification of proteins by isoprenoids in mammalian cells

1990 • 515 citations

Inhibition of Adenylyl Cyclase by G _iα

1993 • 402 citations

Adenylyl cyclases

1992 • 397 citations

Lipid modifications of G proteins: alpha subunits are palmitoylated.

1993 • 336 citations

Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha.

1993 • 293 citations

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.

1990 • 277 citations

The purified alpha subunits of Go and Gi from bovine brain require beta gamma for association with phospholipid vesicles.

1986 • 253 citations

δ-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2

1990 • 252 citations

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

1990 • 225 citations

Acylation of viral and eukaryotic proteins

1989 • 211 citations

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity.

1992 • 205 citations

Tubulin binds specifically to the signal-transducing proteins, Gs alpha and Gi alpha 1.

1990 • 204 citations

A novel N-terminal motif for palmitoylation of G-protein α subunits

1993 • 156 citations

Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go

1988 • 153 citations

Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes.

1989 • 135 citations

Down-regulation of Gi sub-types by prolonged incubation of adipocytes with an A1 adenosine receptor agonist.

1990 • 124 citations

The G protein connection: molecular basis of membrane association

1991 • 114 citations

The G protein .alpha.s subunit incorporates [3H]palmitic acid and mutation of cysteine-3 prevents this modification

1993 • 97 citations

Post-translational processing of Schizosaccharomyces pombe YPT proteins.

1992 • 68 citations

Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G-proteins following transfection of the human alpha 2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor with two pertussis toxin-sensitive G-proteins, Gi2 and Gi3.

1991 • 68 citations

The α‐subunits of G‐proteins G₁₂ and G₁₃ are palmitoylated, but not amidically myristoylated

1994 • 63 citations

Identification of Two Distinct Isoforms of the Guanine Nucleotide Binding Protein G_o in Neuroblastoma × Glioma Hybrid Cells: Independent Regulation During Cyclic AMP‐Induced Differentiation

1990 • 58 citations

Alteration in Gs-mediated signal transduction in S49 lymphoma cells treated with inhibitors of microtubules.

1993 • 55 citations

Conformations of the alpha 39, alpha 41, and beta.gamma components of brain guanine nucleotide-binding proteins. Analysis by limited proteolysis.

1986 • 55 citations

GTP-Binding proteins in brain and neutrophil are tethered to the plasma membrane via their amino termini

1987 • 50 citations

Foetal-calf serum stimulates a pertussis-toxin-sensitive high-affinity GTPase activity in rat glioma C6 BU1 cells

1987 • 47 citations

Myristoylation of the G alpha i2 polypeptide, a G protein alpha subunit, is required for its signaling and transformation functions.

1992 • 45 citations

Translocation of alpha subunits of stimulatory guanine nucleotide-binding proteins through stimulation of the prostacyclin receptor in mouse mastocytoma cells.

1992 • 44 citations

G protein-coupled receptors

1992 • 38 citations

G proteins in cellular control

1992 • 34 citations

Guanine nucleotide regulation of the pertussis and cholera toxin substrates of rat glioma C6 BU1 cells

1987 • 33 citations

Protein targeting: a practical approach

1993 • 28 citations

Protein targeting: A practical approach

1993 • 5 citations