Translocation of alpha subunits of stimulatory guanine nucleotide-binding proteins through stimulation of the prostacyclin receptor in mouse mastocytoma cells.

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

1989 • 374 citations

Human cDNA clones for four species of G alpha s signal transduction protein.

1986 • 370 citations

Molecular basis for two forms of the G protein that stimulates adenylate cyclase.

1986 • 319 citations

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.

1990 • 277 citations

Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.

1987 • 276 citations

The purified alpha subunits of Go and Gi from bovine brain require beta gamma for association with phospholipid vesicles.

1986 • 253 citations

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

1990 • 225 citations

Receptor and effector interactions of G_s Functional studies with antibodies to the α_s carboxyl‐terminal decapeptide

1989 • 176 citations

Carboxyl Rerminal Domain of G _sα Specifies Coupling of Receptors to Stimulation of Adenylyl Cyclase

1988 • 174 citations

Pulmonary and systemic vasodilator effects of the newly discovered prostaglandin, PGI2

1978 • 145 citations

Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes.

1989 • 135 citations

Programmable messengers: a new theory of hormone action

1985 • 115 citations

Cholera Toxin Induces cAMP-independent Degradation of Gs

1989 • 104 citations

Prostaglandin E1-mediated, cyclic AMP-independent, down-regulation of Gs alpha in neuroblastoma x glioma hybrid cells.

1990 • 81 citations

An antibody directed against the carboxyl-terminal decapeptide of the alpha subunit of the retinal GTP-binding protein, transducin. Effects on transducin function.

1988 • 76 citations

Subunit dissociation is the mechanism for hormonal activation of the Gs protein in native membranes.

1988 • 74 citations

Persistent activation of the α subunit of Gs promotes its removal from the plasma membrane

1989 • 73 citations

Inhibition of the release of histamine from rat mast cells: the effect of cold and adrenergic drugs on release of histamine by compound 48-80 and antigen.

1970 • 71 citations

The use of stable prostaglandins to investigate prostacyclin (PGI2)-binding sites and PGI2-sensitive adenylate cyclase in human platelet membranes

1984 • 54 citations

GTP-Binding proteins in brain and neutrophil are tethered to the plasma membrane via their amino termini

1987 • 50 citations

Identification of a prostacyclin receptor coupled to the adenylate cyclase system via a stimulatory GTP-binding protein in mouse mastocytoma P-815 cells

1990 • 46 citations

α‐Subunits of N_s are released from the plasma membrane following cholera toxin activation

1986 • 41 citations

Differential regulation of thrombin- or ATP-induced mobilization of intracellular Ca2+ by prostacyclin receptor in mouse mastocytoma cells

1991 • 11 citations