The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION

1966 • 3,631 citations

The influence of some cations on an adenosine triphosphatase from peripheral nerves

1957 • 2,211 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

1979 • 1,504 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

The structure of an antigenic determinant in a protein

1984 • 841 citations

Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases

1986 • 801 citations

The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family

1989 • 535 citations

ATP formation caused by acid-base transition of spinach chloroplasts.

1966 • 493 citations

Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein.

1987 • 439 citations

Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases

1994 • 430 citations

The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.

1992 • 429 citations

Molecular Genetics of Na,K-ATPase

1990 • 411 citations

Isolation of the yeast calmodulin gene: Calmodulin is an essential protein

1986 • 400 citations

A novel P‐type ATPase from yeast involved in sodium transport

1991 • 362 citations

The protein phosphatase calcineurin is essential for NaCl tolerance of Saccharomyces cerevisiae.

1994 • 362 citations

Tandem gene amplification mediates copper resistance in yeast.

1982 • 354 citations

The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.

1994 • 319 citations

Can calmodulin function without binding calcium?

1991 • 318 citations

Nitrogen Catabolite Repression in Yeasts and Filamentous Fungi

1985 • 315 citations

[11] DNA of Saccharomyces cerevisiae

1991 • 308 citations

Dual Calcium Ion Regulation of Calcineurin by Calmodulin and Calcineurin B

1994 • 303 citations

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase.

1991 • 297 citations

Performance and conservation of osmotic work by proton-coupled solute porter systems

1973 • 279 citations

Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions.

1993 • 274 citations

[40] H+-ATPase from plasma membranes of Saccharomyces cerevisiae and Avena sativa roots: Purification and reconstitution

1988 • 265 citations

Identification and primary structure of a calmodulin binding domain of the Ca2+ pump of human erythrocytes.

1988 • 258 citations

The redundancy of ribosomal and transfer RNA genes in Saccharomyces cerevisiae

1969 • 257 citations

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone.

1992 • 244 citations

The NUP1 gene encodes an essential component of the yeast nuclear pore complex

1990 • 219 citations

Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae

1993 • 206 citations

Two Genes Required for Cell Fusion During Yeast Conjugation: Evidence for a Pheromone-Induced Surface Protein

1987 • 205 citations

Maturation of the yeast plasma membrane [H+]ATPase involves phosphorylation during intracellular transport.

1991 • 199 citations

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from α-factor arrest in yeast

1992 • 195 citations

Characterization of the plasma membrane ATPase of Saccharomyces cerevisiae

1978 • 191 citations

Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment.

1992 • 179 citations

TheSaccharomyces cerevisiae genes (CMP1 andCMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B

1991 • 179 citations

Properties of Yeast Transformation

1979 • 173 citations

Gene amplification at a locus encoding a putative Na+/H+ antiporter confers sodium and lithium tolerance in fission yeast.

1992 • 168 citations

The essential mitotic target of calmodulin is the 110-kilodalton component of the spindle pole body in Saccharomyces cerevisiae.

1993 • 145 citations

Diverse Essential Functions Revealed by Complementing Yeast Calmodulin Mutants

1994 • 142 citations

Calcineurin

1988 • 132 citations

Deletion analysis of yeast plasma membrane H⁺ ‐ATPase and identification of a regulatory domain at the carboxyl‐terminus

1989 • 129 citations

PMT1, the gene for a key enzyme of protein O-glycosylation in Saccharomyces cerevisiae.

1993 • 116 citations

Analysis of the regulatory domain of yeast plasma membrane H⁺‐ATPase by directed mutagenesis and intragenic suppression

1991 • 109 citations

cDNA cloning of a calcineurin B homolog in Saccharomyces cerevisiae

1991 • 95 citations

Positive selection of general amino acid permease mutants in Saccharomyces cerevisiae

1975 • 91 citations

Proliferation of intracellular structures upon overexpression of the PMA2 ATPase in Saccharomyces cerevisiae.

1993 • 88 citations

A temperature-sensitive calmodulin mutant loses viability during mitosis.

1992 • 82 citations

Regulatory Subunit (CNB1 Gene Product) of Yeast Ca²⁺/Calmodulin-Dependent Phosphoprotein Phosphatases Is Required for Adaptation to Pheromone

1992 • 82 citations

The Essential Mitotic Target of Calmodulin is the 110-Kilodalton Component of the Spindle Pole Body in Saccharomyces cerevisiae

1993 • 48 citations

APMR2 tandem repeat with a modified C-terminus is located downstream from theKRS1 gene encoding lysyl-tRNA synthetase inSaccharomyces cerevisiae

1991 • 20 citations

Molecular Perspectives of Monovalent Cation Selective Transmembrane Channels

1979 • 10 citations

The C-terminal 165 amino acids of the plasma membrane Ca(2+)-ATPase confer Ca2+/calmodulin sensitivity on the Na+,K(+)-ATPase alpha-subunit.

1995 • 10 citations

[Li+ as a Na+ analog in ion transport process in vertebrates].

1991 • 3 citations

Interaction of neurotoxins with the selectivity filter and the gating system of the sodium channel.

1979 • 3 citations