Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions.

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

1991 • 1,937 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases

1986 • 801 citations

The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family

1989 • 535 citations

The proton-translocating ATPase of the fungal plasma membrane

1981 • 493 citations

A novel P‐type ATPase from yeast involved in sodium transport

1991 • 362 citations

Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.

1991 • 307 citations

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase.

1991 • 297 citations

Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cells.

1993 • 250 citations

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone.

1992 • 244 citations

A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast.

1992 • 203 citations

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from α-factor arrest in yeast

1992 • 195 citations

Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells.

1992 • 191 citations

TheSaccharomyces cerevisiae genes (CMP1 andCMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B

1991 • 179 citations

Gene amplification at a locus encoding a putative Na+/H+ antiporter confers sodium and lithium tolerance in fission yeast.

1992 • 168 citations

Calcineurin

1988 • 132 citations

A second transport ATPase gene in Saccharomyces cerevisiae.

1988 • 125 citations

FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins.

1991 • 98 citations

cDNA cloning of a calcineurin B homolog in Saccharomyces cerevisiae

1991 • 95 citations

Regulatory Subunit (CNB1 Gene Product) of Yeast Ca²⁺/Calmodulin-Dependent Phosphoprotein Phosphatases Is Required for Adaptation to Pheromone

1992 • 82 citations

Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1.

1991 • 43 citations

The mechanism of sodium efflux in yeast

1982 • 40 citations

Ca²⁺/calmodulin‐activated protein phosphatase

1992 • 22 citations