Insulin-like Growth Factor Binding Proteins

Parental imprinting of the mouse insulin-like growth factor II gene

1991 • 1,773 citations

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

1990 • 1,650 citations

Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies

1986 • 1,158 citations

Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

The Transforming Growth Factor-βs

1991 • 882 citations

An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I.

1987 • 682 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

Binding proteins for the insulin-like growth factors: Structure, regulation and function

1989 • 565 citations

Short-Term Metabolic Effects of Recombinant Human Insulin-like Growth Factor I in Healthy Adults

1987 • 554 citations

Radioimmunoassay of growth hormone-dependent insulinlike growth factor binding protein in human plasma.

1986 • 524 citations

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

1991 • 521 citations

Insulin-like growth factors I and II in healthy man.

1989 • 513 citations

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

1988 • 506 citations

Insulin Regulates the Serum Levels of Low Molecular Weight Insulin-Like Growth Factor-Binding Protein*

1988 • 489 citations

Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts

1988 • 488 citations

A Specific Radioimmunoassay for the Growth Hormone (GH)-Dependent Somatomedin-Binding Protein: Its Use for Diagnosis of GH Deficiency

1990 • 460 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.

1988 • 424 citations

Serum Insulin-Like Growth Factors and Insulin-Like Growth Factor Binding Proteins in the Human Fetus. Relationships with Growth in Normal Subjects and in Subjects with Intrauterine Growth Retardation

1991 • 415 citations

Insulin-Like Growth Factor Binding Proteins in Maternal Serum Throughout Gestation and in the Puerperium: Effects of a Pregnancy-Associated Serum Protease Activity*

1990 • 368 citations

Cloning and Expression of the Growth Hormone-Dependent Insulin-Like Growth Factor-Binding Protein

1988 • 367 citations

“Spontaneous” differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II

1991 • 365 citations

Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action.

1989 • 358 citations

Evidence of Enzymatic Degradation of Insulin-Like Growth Factor-Binding Proteins in the 150K Complex during Pregnancy*

1990 • 349 citations

Insulin-like growth factor-binding protein from human plasma. Purification and characterization.

1986 • 343 citations

Insulin-Like Growth Factor I (IGF-I)-Binding Protein Complex Is a Better Mitogen than Free IGF-I*

1989 • 318 citations

High molecular weight insulin-like growth factor binding protein complex

1989 • 315 citations

Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human

1991 • 313 citations

Structure of the Mr 140,000 growth hormone-dependent insulin-like growth factor binding protein complex: determination by reconstitution and affinity-labeling.

1989 • 308 citations

Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats.

1986 • 306 citations

Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion.

1992 • 295 citations

Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I.

1991 • 294 citations

HNF-1, a member of a novel class of dimerizing homeodomain proteins.

1991 • 286 citations

Amino acid distributions around O-linked glycosylation sites

1991 • 278 citations

Regulation of gene expression by insulin

1991 • 278 citations

Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex.

1992 • 265 citations

Nucleotide Sequence and Expression of a cDNA Clone Encoding a Fetal Rat Binding Protein for Insulin-like Growth Factors

1989 • 263 citations

INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-1 MODULATES BLOOD GLUCOSE LEVELS

1991 • 262 citations

Circulating Levels and Molecular Distribution of the Acid-Labile (α) Subunit of the High Molecular Weight Insulin-Like Growth Factor-Binding Protein Complex*

1990 • 259 citations

Insulin-Like Growth Factor-I Stimulates Terminal Myogenic Differentiation by Induction of Myogenin Gene Expression

1991 • 258 citations

Isolation and characterization of a cDNA encoding the low molecular weight insulin-like growth factor binding protein (IBP-1).

1988 • 254 citations

Growth hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I

1988 • 253 citations

Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2).

1989 • 240 citations

Molecular Cloning of the cDNAs Encoding a Novel Insulin-Like Growth Factor-Binding Protein from Rat and Human

1990 • 239 citations

Characterization of the Acid-Labile Subunit of the Growth Hormone-Dependent Insulin-Like Growth Factor Binding Protein Complex*

1988 • 239 citations

Insulin-Like Growth Factor Receptors

1991 • 235 citations

Purification of a 31,000-dalton insulin-like growth factor binding protein from human amniotic fluid. Isolation of two forms with different biologic actions.

1988 • 233 citations

Isolation and Molecular Cloning of Insulin-Like Growth Factor-Binding Protein-6

1991 • 233 citations

Radioimmunoassay of a 26,000-Dalton Plasma Insulin-Like Growth Factor-Binding Protein: Control by Nutritional Variables*

1988 • 231 citations

Insulin-like Growth Factors (IGF) in Muscle Development

1989 • 228 citations

Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1.

1991 • 221 citations

Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophysectomized and diabetic rats.

1989 • 221 citations

Increased Activity of Insulin-Like Growth Factor (IGF) in Osteoblastic Cells in the Presence of Growth Hormone (GH): Positive Correlation with the Presence of the GHInduced IGF-Binding Protein BP-3

1990 • 216 citations

Insulin-Like Growth Factor (IGF) and IGF-Binding Proteins: Comparison of Human Serum and Lymph*

1988 • 216 citations

Insulin-like Growth Factors: Molecular and Cellular Aspects

1992 • 214 citations

Variables Controlling the Secretion of Insulin-Like Growth Factor Binding Protein-2 in Normal Human Subjects*

1991 • 213 citations

Primary structure of human insulin‐like growth factor‐binding protein/placental protein 12 and tissue‐specific expression of its mRNA

1988 • 210 citations

Insulin-Like Growth Factors

1991 • 206 citations

Inhibitory Insulin-Like Growth Factor-Binding Protein: Cloning, Complete Sequence, and Physiological Regulation

1990 • 204 citations

The induction of a specific protease for insulin-like growth factor binding protein-3 in the circulation during severe illness

1991 • 199 citations

Dose-Response Characteristics for Suppression of Low Molecular Weight Plasma Insulin-Like Growth Factor-Binding Protein by Insulin*

1989 • 196 citations

Expression of Insulin-Like Growth Factor I Stimulates Normal Somatic Growth in Growth Hormone-Deficient Transgenic Mice

1990 • 195 citations

The Somatomedin C Binding Protein: Evidence for a Heterologous Subunit Structure*

1980 • 193 citations

Insulin-like growth factor II stimulates calcium influx in competent BALB/c 3T3 cells primed with epidermal growth factor. Characteristics of calcium influx and involvement of GTP-binding protein.

1987 • 192 citations

Molecular Forms of Serum Insulin-Like Growth Factor (IGF)-Binding Proteins in Man: Relationships with Growth Hormone and IGFs and Physiological Significance*

1989 • 190 citations

Characterization of recombinant human insulin-like growth factor binding proteins 4, 5, and 6 produced in yeast.

1992 • 183 citations

Nutrient Balance and Stage of Lactation Affect Responses of Insulin, Insulin-Like Growth Factors I and II, and Insulin-Like Growth Factor-Binding Protein 2 to Somatotropin Administration in Dairy Cows

1991 • 180 citations

IGF binding proteins: regulation of cellular actions.

1992 • 176 citations

INSULIN DIFFERENTIALLY ALTERS TRANSCAPILLARY MOVEMENT OF INTRAVASCULAR IGFBP-1, IGFBP-2 AND ENDOTHELIAL CELL IGF-BINDING PROTEINS IN THE RAT HEART

1990 • 175 citations

Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor.

1990 • 171 citations

Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: A potential candidate for fixing IGF-II in human bone

1991 • 169 citations

Possible Direct Linkage of Insulin-like Growth Factor-II Receptor with Guanine Nucleotide-binding Proteins

1989 • 169 citations

Radioimmunoassay of placental protein 12: Levels in amniotic fluid, cord blood, and serum of healthy adults, pregnant women, and patients with trophoblastic disease

1982 • 168 citations

Different Tissue Distribution and Hormonal Regulation of Messenger RNAs Encoding Rat Insulin-Like Growth Factor-Binding Proteins-1 and -2

1990 • 165 citations

An Insulin-Like Growth Factor-Binding Protein in Ovarian Follicular Fluid Blocks Follicle-Stimulating Hormone-Stimulated Steroid Production by Ovarian Granulosa Cells*

1989 • 163 citations

Structural and Biological Characterization of Bovine Insulin-Like Growth Factor Binding Protein-3*

1990 • 160 citations

A Low Molecular Weight Insulin-Like Growth Factor Binding Protein from Rat: cDNA Cloning and Tissue Distribution of its Messenger RNA

1989 • 158 citations

Insulin-Like Growth Factor-Binding Protein (IGF-BP) Inhibition of Granulosa Cell Function: Effect on Cyclic Adenosine 3’5’-Monophosphate, Deoxyribonucleic Acid Synthesis, and Comparison with the Effect of an IGF-I Antibody*

1990 • 158 citations

Regulation of Serum Insulin-Like Growth Factor-I (IGF I) and IGF Binding Proteins during Rat Pregnancy*

1990 • 156 citations

Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1

1989 • 154 citations

Insulin regulates the 35 kDa IGF binding protein in patients with diabetes mellitus

1988 • 150 citations

A Simple Assay for Proteolysis of IGFBP-3

1991 • 149 citations

Effect of Dietary Protein Deprivation on Insulin-Like Growth Factor (IGF)-I and -II, IGF Binding Protein-2, and Serum Albumin Gene Expression in Rat*

1990 • 148 citations

Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia.

1990 • 148 citations

The design, expression, and characterization of human insulin-like growth factor II (IGF-II) mutants specific for either the IGF-II/cation-independent mannose 6-phosphate receptor or IGF-I receptor.

1991 • 146 citations

Peptide Growth Factors and Their Receptors I

1991 • 145 citations

Regulation of Insulin-Like Growth Factor-Binding Protein-1 Synthesis and Secretion by Progestin and Relaxin in Long Term Cultures of Human Endometrial Stromal Cells*

1991 • 144 citations

Insulin‐like growth factor (IGF) binding to human fibroblast and glioblastoma cells: The modulating effect of cell released IGF binding proteins (IGFBPs)

1990 • 143 citations

Insulin-Like Growth Factor-I (IGF-I) Infusion into Hypophysectomized or Protein-Deprived Rats Induces Specific IGF-Binding Proteins in Serum*

1989 • 143 citations

Two Immunoreactive Binding Proteins for Insulin-Like Growth Factors in Human Amniotic Fluid: Relationship to Fetal Maturity*

1987 • 142 citations

Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex.

1992 • 141 citations

Synthesis of Placental Protein 12 by Human Endometrium*

1986 • 139 citations

Transcapillary Permeability and Subendothelial Distribution of Endothelial and Amniotic Fluid Insulin- Like Growth Factor Binding Proteins in the Rat Heart*

1990 • 139 citations

Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors.

1989 • 139 citations

Synthesis of Placental Protein 12 by Human Decidua

1985 • 139 citations

The 25-KiloDalton Insulin-Like Growth Factor (IGF)-Binding Protein Inhibits both Basal and IGF-I-Mediated Growth of Chick Embryo Pelvic Cartilagein Vitro

1990 • 136 citations

Insulin-Like Growth Factor Binding Protein Secretion by Breast Carcinoma Cell Lines: Correlation with Estrogen Receptor Status*

1990 • 135 citations

Gene expression of insulin-like growth factors (IGFs), the type 1 IGF receptor, and IGF-binding proteins in dexamethasone-induced fetal growth retardation.

1992 • 133 citations

1,25-Dihydroxyvitamin D3 Differentially Regulates the Production of Insulin-Like Growth Factor I (IGF-I) and IGF-Binding Protein-4 in Mouse Osteoblasts*

1991 • 132 citations

Insulin-like growth factor binding protein-3. Organization of the human chromosomal gene and demonstration of promoter activity.

1990 • 131 citations

Insulin-Like Growth Factor (IGF)-Binding Protein-3 Blocks IGF-I-Induced Receptor Down-Regulation and Cell Desensitization in Cultured Bovine Fibroblasts*

1991 • 130 citations

Glycosylation of Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) is not Required for Potentiation IGF-I Action: Evidence for Processing of Cell-Bound IGFBP-3*

1991 • 127 citations

Multihormonal Regulation of Insulin-Like Growth Factor-Binding Protein-1 in Rat H4IIE Hepatoma Cells: The Dominant Role of Insulin*

1991 • 127 citations

Tissue-Specific Expression of Four Insulin-Like Growth Factor-Binding Proteins (1, 2, 3, and 4) in the Rat Ovary*

1991 • 125 citations

Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA

1989 • 125 citations

Expression of the Genes for Insulin-Like Growth Factor-I (IGF-I), IGF-II, and IGF-Binding Proteins-1 and -2 in Fetal Rat under Conditions of Intrauterine Growth Retardation Caused by Maternal Fasting*

1991 • 124 citations

Identification and Characterization of a Rat Decidual Insulin-Like Growth Factor-Binding Protein Complementary DNA

1990 • 124 citations

Metabolic regulation of the growth hormone independent insulin-like growth factor binding protein in human plasma

1988 • 124 citations

Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF I-induced stimulation of osteoblasts: Control of IGF signalling to bone cells by IGFBP-3-specific proteolysis?

1991 • 123 citations

Regulation of Growth Hormone-Independent Insulin Like Growth Factor-Binding Protein (BP-28) in Cultured Human Fetal Liver Explants*

1989 • 122 citations

Insulin‐like growth factor binding protein secretion by muscle cells: Effect of cellular differentiation and proliferation

1988 • 119 citations

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

1989 • 116 citations

Insulin-like growth factor binding proteins from cultured human fibroblasts. Characterization and hormonal regulation.

1989 • 116 citations

Expression of insulin-like growth factor I, its binding proteins, and its receptor in ovarian cancer.

1991 • 115 citations

Characterization of Insulin-Like Growth Factor Binding Proteins Produced in the Rat Central Nervous System*

1990 • 115 citations

Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.

1990 • 114 citations

Human Preovulatory Follicular Fluid, Luteinized Cells of Hyperstimulated Preovulatory Follicles, and Corpus Luteum Contain Placental Protein 12*

1984 • 114 citations

Discrete alterations of the insulin-like growth factor I molecule which alter its affinity for insulin-like growth factor-binding proteins result in changes in bioactivity.

1990 • 114 citations

Effect of in Vitro Action of Serum Proteases or Exposure to Acid on Measurable Immunoreactive Somatomedin-C in Serum*

1983 • 112 citations

Identification by Hybridization Histochemistry of Human Endometrial Cells Expressing mRNAs Encoding a Uterine β-Lactoglobulin Homologue and Insulin-Like Growth Factor-Binding Protein-1

1990 • 112 citations

Ontogeny of Insulin-Like Growth Factors (IGF-I and IGF-II) and IGF-Binding Proteins in Porcine Serum during Fetal and Postnatal Development*

1991 • 112 citations

The gene encoding rat insulinlike growth factor-binding protein 1 is rapidly and highly induced in regenerating liver.

1991 • 110 citations

Release of insulin-like growth factor carrier proteins by osteoblasts: Stimulation by estradiol and growth hormone

1989 • 110 citations

Cloning and sequence determination of bovine insulin‐like growth factor binding protein‐2 (IGFBP‐2): Comparison of its structral and functional properties with IGFBP‐1

1992 • 110 citations

Structural analogs of human insulin-like growth factor I with reduced affinity for serum binding proteins and the type 2 insulin-like growth factor receptor.

1988 • 110 citations

Retinoid Modulation of Insulin-Like Growth Factor-Binding Proteins and Inhibition of Breast Carcinoma Proliferation*

1991 • 110 citations

Insulin-like growth factor binding proteins: gene structure and expression.

1992 • 110 citations

Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum

1991 • 109 citations

Prolonged Exercise Increases Serum Insulin-Like Growth Factor-Binding Protein Concentrations*

1989 • 109 citations

Characterization of an Insulin-Like Growth Factor Binding Protein (IGFBP-4) Produced by the B104 Rat Neuronal Cell Line: Chemical and Biological Properties and Differential Synthesis by Sublines*

1991 • 109 citations

Ontogeny of Serum Insulin-Like Growth Factor Binding Proteins in the Rat*

1989 • 106 citations

Isolierung und Charakterisierung eines neuen plazentaspezifischen Proteins (PP12)

1980 • 106 citations

Impaired Formation of the Ternary Insulin-Like Growth Factor-Binding Protein Complex in Patients with Hypoglycemia due to Nonislet Cell Tumors*

1991 • 105 citations

Liberation of Immunoreactive Somatomedin-C from Its Binding Proteins by Proteolytic Enzymes and Heparin*

1983 • 105 citations

Use of Insulin-Like Growth Factor-Binding Protein 3 for the Evaluation of Growth Disorders

1990 • 104 citations

Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts.

1990 • 103 citations

SERUM IMMUNOREACTIVE SOMATOMEDIN-C IS ELEVATED LATE IN PREGNANCY¹

1978 • 102 citations

Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats

1992 • 102 citations

HUMAN GRANULOSA CELLS SYNTHESIZE LOW MOLECULAR WEIGHT INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN

1989 • 102 citations

Insulin-Like Growth Factor (IGF) Binding to Cell Monolayers Is Directly Modulated by the Addition of IGF-Binding Proteins*

1991 • 102 citations

Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of senescent and quiescent human fibroblasts.

1991 • 101 citations

The Expression Pattern of an Insulin-Like Growth Factor (IGF)-Binding Protein Gene Is Distinct from IGF-II in the Midgestational Rat Embryo

1990 • 100 citations

CIRCULATING LEVELS OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-1 (IGFBP-1) AND HEPATIC mRNA ARE INCREASED IN THE SMALL FOR GESTATIONAL AGE (SGA) FETAL RAT

1990 • 100 citations

Molecular cloning of a new human insulin-like growth factor binding protein

1991 • 100 citations

Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex.

1992 • 99 citations

Insulin-Like Growth Factor Binding Proteins in Human Endometrium: Steroid-Dependent Messenger Ribonucleic Acid Expression and Protein Synthesis*

1991 • 98 citations

Insulin-like growth factor-binding protein-1 is phosphorylated by cultured human endometrial stromal cells and multiple protein kinases in vitro.

1991 • 97 citations

Tissue, Developmental, and Metabolic Regulation of Messenger Ribonucleic Acid Encoding a Rat Insulin-Like Growth Factor-Binding Protein*

1990 • 96 citations

The Fetal Rat Binding Protein for Insulin-Like Growth Factors is Expressed in the Choroid Plexus and Cerebrospinal Fluid of Adult Rats

1989 • 94 citations

Insulin-Dependent Regulation of Insulin-Like Growth Factor-Binding Protein-1*

1990 • 94 citations

Recombinant human [Cys281]insulin-like growth factor-binding protein 2 inhibits both basal and insulin-like growth factor I-stimulated proliferation and collagen synthesis in fetal rat calvariae.

1991 • 92 citations

Two Insulin-Like Growth Factor (IGF)-Binding Proteins Are Responsible for the Selective Affinity for IGF-II of Cerebrospinal Fluid Binding Proteins*

1991 • 91 citations

Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein.

1991 • 90 citations

Identification of the types of insulin-like growth factor-binding proteins that are secreted by muscle cells in vitro

1989 • 90 citations

Tissue distribution and regulation of insulin-like growth factor (IGF)-binding protein-3 messenger ribonucleic acid (mRNA) in the rat: comparison with IGF-I mRNA expression.

1992 • 90 citations

Natural and synthetic forms of insulin-like growth factor-1 (IGF-1) and the potent derivative, destripeptide IGF-1: Biological activities and receptor binding

1987 • 90 citations

IGF Binding Proteins in Growth-Retarded Children with Chronic Renal Failure

1989 • 90 citations

Production of Insulin-Like Growth Factor Binding Proteins (IGFBPs) by Porcine Granulosa Cells: Identification of IGFBP-2 and -3 and Regulation by Hormones and Growth Factors*

1990 • 88 citations

Immunological distribution of one form of insulin-like growth factor (IGF)-binding protein and IGF peptides in human fetal tissues

1989 • 88 citations

Production of Insulin-Like Growth Factors and Their Binding Proteins by Rabbit Articular Chondrocytes: Relationships with Cell Multiplication*

1989 • 87 citations

Differential Effects of Insulin-like Growth Factor (IGF)- I and IGF-II on the Expression of IGF Binding Proteins (IGFBPs) in a Rat Neuroblastoma Cell Line: Isolation and Characterization of Two Forms of IGFBP-4*

1991 • 87 citations

Characterization of Somatomedin Binding in Human Serum by Ultracentrifugation and Gel Filtration*

1982 • 86 citations

Structural characterization of a follicle-stimulating hormone action inhibitor in porcine ovarian follicular fluid. Its identification as the insulin-like growth factor-binding protein.

1990 • 84 citations

Human insulin-like growth factor binding protein-6 is O-glycosylated

1992 • 84 citations

Evidence for an Insulin‐Like Growth Factor Autocrine‐Paracrine System in the Retinal Photoreceptor‐Pigment Epithelial Cell Complex

1991 • 83 citations

A novel human insulin-like growth factor binding protein secreted by osteoblast-like cells

1991 • 82 citations

The Directin VitroEffect of Insulin-Like Growth Factors (IGFs) on Normal Bovine Mammary Cell Proliferation and Production of IGF Binding Proteins

1991 • 82 citations

Regulation of insulin-like growth factor-binding proteins in serum and lymph of lactating cows by somatotropin.

1992 • 82 citations

Regulation of Insulin-Like Growth Factor (IGF) Binding Proteins in Transgenic Mice with Altered Expression of Growth Hormone and IGF-I

1991 • 81 citations

Insulin-Like Growth Factor Binding Protein-3 Secretion from Cultured Rat Sertoli Cells: Dual Regulation by Follicle Stimulating Hormone and Insulin-Like Growth Factor-I

1990 • 80 citations

Insulin Regulation of Insulin-Like Growth Factor-Binding Protein Production in Cultured HepG2 Cells*

1990 • 79 citations

Insulin-Like Growth Factor-Binding Proteins (IGF-BPs) Produced by Human Skin Fibroblasts: Immunological Relationship to Other Human IGF-BPs*

1988 • 78 citations

Insulin Regulates the Expression of the Insulin-Like Growth Factor Binding Protein 2 mRNA in Rat Hepatocytes

1990 • 78 citations

Dexamethasone Increases Hepatic Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) mRNA and Serum IGFBP-1 Concentrations in the Rat*

1990 • 78 citations

Transforming Growth Factor-β Stimulates Production of Insulin-Like Growth Factor-Binding Protein-3 by Human Skin Fibroblasts*

1991 • 77 citations

Isolation and NH2-terminal amino acid sequences of rat serum carrier proteins for insulin-like growth factors

1988 • 76 citations

A unique receptor-independent mechanism by which insulinlike growth factor I regulates the availability of insulinlike growth factor binding proteins in normal and transformed human fibroblasts.

1991 • 75 citations

CHANGES IN THE CIRCULATING FORM OF SERUM SOMATOMEDIN-C DURING FETAL LIFE

1980 • 73 citations

Insulin-like growth factor-binding protein-3 is functionally normal in pregnancy serum.

1992 • 73 citations

Cloning and characterization of the growth hormone-dependent insulin-like growth factor binding protein (IGFBP-3) in the rat

1990 • 73 citations

Ovarian Granulosa Cell-Derived Insulin-Like Growth Factor Binding Proteins: Modulatory Role of Follicle- Stimulating Hormone*

1991 • 72 citations

Expression of Two Insulin-Like Growth Factor-Binding Proteins in a Human Endometrial Cancer Cell Line: Structural, Immunological, and Genetic Characterization*

1989 • 71 citations

Structure, Specificity, and Regulation of the Insulin- Like Growth Factor-Binding Proteins in Adult Rat Serum*

1989 • 71 citations

Rat astroglial somatomedin/insulin-like growth factor binding proteins: characterization and evidence of biologic function

1988 • 70 citations

Insulin-like growth factor-binding protein-1: A role in glucose counterregulation?

1991 • 70 citations

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide

1989 • 70 citations

Classification of the insulin-like growth factor binding proteins into three distinct categories according to their binding specificities

1988 • 70 citations

Report On The Nomenclature Of The IGF Binding Proteins

1990 • 70 citations

Radioimmunoassay of insulin-like growth factor-binding protein-6 in human serum and other body fluids

1992 • 70 citations

Parathyroid Hormone and Parathyroid Hormone-Related Peptide Stimulate Insulin-Like Growth Factor-Binding Protein Secretion by Rat Osteoblast-Like Cells through a Adenosine 3′,5′-Monophosphate-Dependent Mechanism*

1991 • 70 citations

Serum Half-Life and Biological Activity of Mutants of Human Insulin-Like Growth Factor I which Do Not Bind to Serum Binding Proteins

1988 • 69 citations

Anatomical relationships in the patterns of insulin-like growth factor (IGF)-I, IGF binding protein-1, and IGF-I receptor gene expression in the rat kidney.

1992 • 69 citations

Immunohistological Localization of the Human Endometrial Secretory Protein Pregnancy-Associated Endometrialα₁-Globulin, an Insulin-Like Growth Factor-Binding Protein, During the Menstrual Cycle*

1988 • 69 citations

Gene expression of insulin-like growth factors (IGFs), the type 1 IGF receptor, and IGF-binding proteins in dexamethasone-induced fetal growth retardation

1992 • 69 citations

Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors

1991 • 69 citations

Differential regulation of insulin-like growth factor binding protein secretion from human decidual cells by IGF-I, insulin, and relaxin.

1990 • 68 citations

Insulin-like growth factor (IGF)-binding protein release by human fetal fibroblasts: dependency on cell density and IGF peptides

1989 • 68 citations

Inhibitors of Glucose Uptake Stimulate the Production of Insulin-Like Growth Factor-Binding Protein (IGFBP-1) by Human Fetal Liver*

1990 • 68 citations

Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs

1992 • 68 citations

Insulin-Like Growth Factors I and II and Their Binding Proteins in Rat Milk

1991 • 68 citations

Characterization of Insulin-Like Growth Factor Binding Proteins (IGFBPs) during Gestation in Mice: Effects of Hypophysectomy and an IGFBP-Specific Serum Protease Activity*

1990 • 68 citations

Regulation of Insulin-Like Growth Factor (IGF)-Binding Protein Synthesis by Insulin and IGF-I in Cultured Bovine Fibroblasts*

1990 • 67 citations

Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I), IGF-II and des(1–3)IGF-I in rats

1991 • 67 citations

Transcriptional Regulation of Rat Insulin-Like Growth Factor-Binding Protein-1 Expression by Growth Hormone

1990 • 66 citations

Dexamethasone and 1,25-Dihydroxyvitamin D₃Modulation of Insulin-Like Growth Factor-Binding Proteins in Rat Osteoblast-Like Cell Cultures

1991 • 66 citations

Binding proteins for insulin-like growth factors in adult rat serum. Comparison with other human and rat binding proteins

1987 • 66 citations

Regulation of Low Molecular Weight Insulin-Like Growth Factor Binding Proteins in Experimental Diabetes Mellitus*

1990 • 65 citations

Specific Decrease in Liver Insulin-Like Growth Factor-I and Brain Insulin-Like Growth Factor-II Gene Expression in Energy-Restricted Rats

1991 • 65 citations

Enhanced Expression of Insulin-Like Growth Factor-Binding Protein-I in the Fasted Rat: The Effects of Insulin and Growth Hormone Administration*

1991 • 65 citations

The promoter of the human gene for insulin-like growth factor binding protein-1. Basal promoter activity in HEP G2 cells depends upon liver factor B1.

1990 • 64 citations

Insulin Rapidly Inhibits Insulin-Like Growth Factor-Binding Protein-1 Gene Expression in H4-II-E Rat Hepatoma Cells

1991 • 64 citations

The Differential Regulation by Glucagon and Growth Hormone of Insulin-Like Growth Factor (IGF)-I and IGF Binding Proteins in Cultured Rat Hepatocytes*

1991 • 64 citations

Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex

1992 • 64 citations

Insulin-like growth factor system gene expression in the human kidney.

1992 • 63 citations

Insulin-like growth factor-I and its association with binding proteins in bovine milk

1989 • 63 citations

Regulation of Insulin-Like Growth Factor Binding Protein Synthesis and Secretion in a Bovine Epithelial Cell Line^*

1991 • 63 citations

A factor contained in plasma is required for IGF binding protein‐1 to potentiate the effect of IGF‐I on smooth muscle cell DNA synthesis

1990 • 63 citations

Structural and Immunological Comparison of Insulin-Like Growth Factor Binding Proteins of Cerebrospinal and Amniotic Fluids*

1989 • 63 citations

Insulin-Like Growth Factor-Binding Proteins from Vascular Endothelial Cells: Purification, Characterization, and Intrinsic Biological Activities*

1989 • 62 citations

An Insulin-Like Growth Factor-Binding Protein in the Baboon (Papio anubis) Endometrium: Synthesis, Immunocytochemical Localization, and Hormonal Regulation*

1989 • 62 citations

Evaluation of the Developmental and Nutritional Changes in Porcine Insulin-Like Growth Factor-Binding Protein-1 and -2 Serum Levels by Immunoassay*

1991 • 62 citations

The physiological role of IGFBP-1.

1991 • 62 citations

Structural determinants for binary and ternary complex formation between insulin-like growth factor-I (IGF-I) and IGF binding protein-3.

1992 • 61 citations

Insulin‐Like growth factor binding protein (IGFBP) inhibits igf action on human osteosarcoma cells

1991 • 61 citations

Expression of the IGFBP-2 gene in post-implantation rat embryos

1992 • 61 citations

The insulin-like growth factor binding protein BP-25 is expressed by human breast cancer cells

1989 • 61 citations

Identification of the insulin-like growth factor binding proteins 5 and 6 (IGFBP-5 and 6) in human breast cancer cells

1992 • 60 citations

Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex

1992 • 59 citations

The Binding Characteristics and Biological Effects in FRTL5 Cells of Placental Protein-12, an Insulin-Like Growth Factor-Binding Protein Purified from Human Amniotic Fluid*

1989 • 59 citations

Expression of the BRL-3A Insulin-like Growth Factor Binding Protein (rBP-30) in the Rat Central Nervous System

1989 • 59 citations

Secretion and biological actions of insulin‐like growth factor binding proteins in two human tumor‐derived cell lines in vitro

1991 • 59 citations

Glycosaminoglycans inhibit formation of the 140 kDa insulin-like growth factor-binding protein complex

1990 • 58 citations

Production of IGF-binding proteins by vascular endothelial cells

1987 • 58 citations

Dexamethasone Stimulates Transcription of the Insulin-Like Growth Factor-Binding Protein-1 Gene in H4-II-E Rat Hepatoma Cells

1990 • 57 citations

Tissue-specific expression of insulin-like growth factor binding protein-3 protease activity during rat pregnancy.

1992 • 56 citations

Production of carrier proteins for insulin‐like growth factors (IGFs) by rat osteoblastic cells Regulation by IGF I and cortisol

1989 • 56 citations

IDENTIFICATION OF INSULIN-UKE GROWTH FACTOR-BINDING PROTEIN-2 (IGF-BP-2) AND A LOW MOLECULAR WEIGHT IGF-BP IN HUMAN SEMINAL PLASMA

1990 • 56 citations

Ovarian Intrabursal Administration of Insulin-Like Growth Factor-Binding Protein Inhibits Follicle Rupture in Gonadotropin-Treated Immature Female Rats1

1991 • 56 citations

Cloning of the Rat Insulin-Like Growth Factor-Binding Protein-2 Gene and Identification of a Functional Promoter Lacking a TATA Box

1990 • 56 citations

Identification of a novel binding protein for insulin-like growth factors in adult rat serum

1989 • 55 citations

The Multifunctional Nature of Peptide Growth Factors

1991 • 55 citations

Three Distinct Forms of Insulin-Like Growth Factor Binding Proteins are Released by Decidual Cells in Culture*

1990 • 54 citations

Circulating levels of insulin-like growth factors increase and molecular forms of their serum binding proteins change with human pregnancy

1990 • 54 citations

Expression of Insulinlike Growth Factor (IGF) and IGF-Binding Protein Genes in Human Lung Tumor Cell Lines

1992 • 53 citations

Structure of the Human Chromosomal Gene for the 25 Kilodalton Insulin-Like Growth Factor Binding Protein

1989 • 52 citations

AN INHIBITORY INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN (IN-IGFBP) FROM HUMAN PROSTATIC CELL CONDITIONED MEDIUM REVEALS N-TERMINAL SEQUENCE IDENTITY WITH BONE DERIVED IN-IGFBP

1990 • 52 citations

Identification of Insulin-Like Growth Factor-Binding Protein-3 (IGFBP-3) and IGFBP-2 in Human Follicular Fluid*

1990 • 52 citations

Insulin-like growth factor-binding protein-1 inhibits binding of IGF-I on fetal skin fibroblasts but stimulates their DNA synthesis

1990 • 52 citations

Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors

1989 • 51 citations

Molecular biology of the insulin-like growth factors

1990 • 51 citations

Purified Preparations of the Amniotic Fluid-Derived Insulin-Like Growth Factor-Binding Protein Contain Multimeric Forms that Are Biologically Active*

1989 • 51 citations

Human insulin‐like growth‐factor‐binding protein

1989 • 51 citations

Organization of the gene encoding the insulin-like growth factor binding protein IBP-1

1988 • 50 citations

INSULIN-LIKE GROWTH FACTOR (IGF) BINDING PROTEIN-3 IN PREGNANCY SERUM BINDS NATIVE IGF-I BUT NOT IODO-IGF-L

1991 • 50 citations

Further Characterization of Insulin-Like-Growth Factor Binding Proteins in Rat Osteoblast-Like Cell Cultures: Modulation by 17β-Estradiol and Human Growth Hormone

1991 • 50 citations

Inhibitory Diffusible Factor 45 Bifunctional Activity

1989 • 49 citations

An IGF binding protein is an inhibitor of fgf stimulation

1991 • 47 citations

Insulin-like growth factor I and erythropoiesis.

1992 • 46 citations

Regulation of hepatic expression of IGF I and fetal IGF binding protein mRNA in streptozotocin‐diabetic rats

1989 • 46 citations

Characterization of insulin-like growth factor binding proteins in ovine tissue fluids

1989 • 46 citations

Tissue Localization of Perfused Endothelial Cell IGF Binding Protein is Markedly Altered by Association with IGF-I

1990 • 46 citations

Expression of hepatic insulin-like growth factor-I and insulin-like growth factor-binding protein-1 genes is transcriptionally regulated in streptozotocin-diabetic rats.

1992 • 46 citations

Insulin-like Growth Factor II Stimulates Calcium Influx in Competent Balb/c 3T3 Cells Primed with Epidermal Growth Factor

1989 • 46 citations

Molecular forms of human IGF binding proteins: physiological implications.

1991 • 45 citations

Changes in insulin-like growth factor-binding proteins in bovine mammary secretions associated with pregnancy and parturition

1991 • 45 citations

Insulin-like growth factor-binding protein-3 is functionally normal in pregnancy serum

1992 • 45 citations

Regulation of Insulin-Like Growth Factor-Binding Protein-1 Production in Human Granulosa-Luteal Cells*

1989 • 45 citations

Gene expression and secretion of insulin-like growth factor-binding proteins during myoblast differentiation.

1992 • 44 citations

Insulin-Like Growth Factors (IGFs) and IGF-Binding Proteins in the Developing Rhesus Monkey*

1991 • 44 citations

Human granulosa contain messenger ribonucleic acids encoding insulin-like growth factor-binding proteins (IGFBPs) and secrete IGFBPs in culture

1991 • 43 citations

Cloning and characterization of bovine insulin-like growth factor binding protein-3 (bIGFBP-3)

1991 • 43 citations

Mutations in the C-Terminal Part of Insulin-Like Growth Factor (IGF)-Binding Protein-1 Result in Dimer Formation and Loss of IGF Binding Capacity

1991 • 43 citations

Production of an Insulin-Like Growth Factor (IGF)- Inducible IGF-Binding Protein by Human Skin Fibroblasts*

1990 • 43 citations

Potential autocrine role of insulin-like growth factor II during suramin-induced differentiation of HT29-D4 human colonic adenocarcinoma cell line.

1992 • 42 citations

Differential regulation of insulin‐like growth factor binding protein (IGFBP)‐2 mRNA in liver and bone cells by insulin and retinoic acid in vitro

1992 • 41 citations

Insulin rapidly decreases insulin-like growth factor-binding protein-1 gene transcription in streptozotocin-diabetic rats

1992 • 40 citations

HUMAN GRANULOSA CELLS CONTAIN INSULIN‐LIKE GROWTH FACTOR‐BINDING PROTEIN (IGF BP‐1) mRNA

1990 • 40 citations

Techniques in Endocrine Research

1964 • 40 citations

Decidualization and insulin-like growth factor (IGF) binding protein: implications for its role in stromal cell differentiation and the decidual cell in haemochorial placentation

1989 • 40 citations

Structure of the human insulin-like growth factor binding protein-2 gene.

1992 • 39 citations

Expression of insulin and insulin-like growth factor receptors and binding proteins by retinal pigment epithelium

1991 • 39 citations

Identification of Rat Cell Lines that Preferentially Express Insulin-Like Growth Factor Binding Proteins rlGFBP-1, 2, or 3

1990 • 39 citations

Binding Specificities and Transducing Function of the Different Molecular Weight Forms of Insulin-Like Growth Factor-II (IGF-II) on IGF-I Receptors*

1991 • 39 citations

THE OVARIAN EXPRESSION OF THE ANTIGONADOTROPIC INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-2 IS THECAINTERSTITIAL CELL-SELECTIVE: EVIDENCE FOR HORMONAL REGULATION

1991 • 37 citations

Therapeutic potential of insulinlike growth factor i

1990 • 37 citations

Rat ovarian insulin-like growth factor binding protein-3: a growth hormone-dependent theca-interstitial cell-derived antigonadotropin.

1992 • 36 citations

Insulin-like growth factor-I (IGF-I) and IGF-binding proteins both decline in the rat during late pregnancy

1990 • 36 citations

Lack of Growth Hormone Effect on Insulin-Associated Suppression of Insulinlike Growth Factor Binding Protein 1 in Humans

1990 • 36 citations

Presence of IDF45 (mlGFBP-3) binding sites on chick embryo fibroblasts

1991 • 35 citations

Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2)

1991 • 35 citations

Expression of serum insulin-like growth factors, insulin-like growth factor-binding proteins, and the growth hormone-binding protein in heterozygote relatives of Ecuadorian growth hormone receptor deficient patients

1992 • 35 citations

Insulin-like growth factor binding protein (IGFBP)4 accounts for the connective tissue distribution of endothelial cell IGFBPs perfused through the isolated heart.

1992 • 35 citations

Identification of a type 1 insulin-like growth factor binding protein (IGF BP) in serum from rats with diabetes mellitus

1989 • 35 citations

Intrinsic Bioactivity of Insulin-Like Growth Factor-Binding Proteins from Vascular Endothelial Cells*

1990 • 34 citations

An insulin-like growth factor-binding protein purified from medium conditioned by a human lung fibroblast cell line (He[39]L) has a novel N-terminal sequence

1990 • 34 citations

Regulation of insulin-like growth factor-binding proteins in serum and lymph of lactating cows by somatotropin

1992 • 34 citations

Synthesis of the acid-labile subunit of the growth-hormone-dependent insulin-like-growth-factor-binding protein complex by rat hepatocytes in culture

1991 • 34 citations

Most of the circulating insulin-like growth factors-I and -II are present in the 150 kDa complex during human pregnancy

1991 • 34 citations

Isolation and Amino-terminal Sequence of a Novel Cellular Growth Inhibitor (Inhibitory Diffusible Factor 45) Secreted by 3T3 Fibroblasts

1989 • 33 citations

Effects of exogenous porcine growth hormone on serum insulin-like growth factor-binding proteins in growing pigs

1991 • 33 citations

Structure and localization of the human insulin-like growth factor-binding protein 2 gene

1991 • 32 citations

INSUUN-LIKE GROWTH FACTOR BINDING PROTEINS IN HUMAN BREAST CANCER CELLS: RELATIONSHIP TO hIGFBP-2 AND hIGFBP-3.

1990 • 32 citations

Transcription of the insulin-like growth factor-binding protein-2 gene is increased in neonatal and fasted adult rat liver.

1992 • 32 citations

Characterization of Insulin-Like Growth Factor-Binding Proteins from Sheep Thyroid Cells*

1989 • 31 citations

Expression of the Insulin Like Growth Factor-Binding Protein 3 (IGFBP-3) Gene is Increased in Human Renal Carcinomas

1991 • 31 citations

Characterization of urinary insulin-like growth factor binding proteins

1992 • 31 citations

The gene encoding human low-molecular weight insulin-like growth-factor binding protein (IGF-BP25): regional localization to 7p12–p13 and description of a DNA polymorphism

1989 • 30 citations

Enhanced potency of truncated insulin-like growth factor-I (des(1–3)IGF-I) relative to IGF-I in lit/lit mice

1990 • 30 citations

Site‐directed mutagenesis of the N‐terminal region of IGF binding protein 1; analysis of IGF binding capability

1991 • 29 citations

Differential expression of insulin-like growth factor-I and insulin-like growth factor binding protein-1 in the diabetic rat

1991 • 29 citations

Characterization of the steroid-dependence of insulin-like growth factor-binding protein-2 synthesis and mRNA expression in cultured human endometrial stromal cells

1991 • 29 citations

Porcine Insulin-Like Growth Factor (IGF) Binding Protein Blocks IGF-I Action on Porcine Adipose Tissue

1989 • 29 citations

Cloning of the rat insulin-like growth factor binding protein-1 gene and analysis of its 5′ promoter region

1992 • 28 citations

Cloning and Expression of Human Insulin-Like Growth Factor Binding Protein 3

1990 • 28 citations

Metabolic clearance of insulin-like growth factor-II in sheep

1989 • 28 citations

Developmental Expression of Rat Insulin-Like Growth Factor Binding Protein-2 by Astrocytic Glial Cells in Culture*

1991 • 28 citations

Maternal Insulin-Like Growth Factor-Binding Protein Messenger Ribonucleic Acid during Rat Pregnancy*

1991 • 28 citations

Insulin-like growth factor system gene expression in the human kidney

1992 • 27 citations

Characterization of the increased biological potency in BALB/C 3T3 cells of two analogs of human insulinlike growth factor I which have reduced affinity for the 28 K cell‐derived binding protein

1989 • 27 citations

Distribution of messenger RNAs of insulin-like growth factor(IGF)-binding proteins-1 and -3 between parenchymal and nonparenchymal cells in rat liver.

1991 • 27 citations

Actions of insulin‐like growth factor‐I on the B104 neuronal cell line: Effects on cell replication, receptor characteristics, and influence of secreted binding protein on ligand binding

1989 • 27 citations

The 34 kilodalton insulin-like growth factor binding proteins in human cerebrospinal fluid and the A673 rhabdomyosarcoma cell line are human homologues of the rat BRL-3A binding protein

1989 • 26 citations

Tissue distribution and regulation of insulin-like growth factor (IGF)- binding protein-3 messenger ribonucleic acid (mRNA) in the rat: comparison with IGF-I mRNA expression

1992 • 26 citations

Differential expression of the insulin-like growth factor binding proteins in spontaneously diabetic rats

1992 • 26 citations

Mutants of human insulin‐like growth factor II

1992 • 25 citations

Purification and characterization of human recombinant insulin-like growth factor binding protein 3 expressed in chinese hamster ovary cells

1991 • 25 citations

Gene expression and secretion of insulin-like growth factor-binding proteins during myoblast differentiation

1992 • 25 citations

Mutants of human insulin-like growth factor II: Expression and characterization of analogs with a substitution of Tyr27 and/or a deletion of residues 62–67

1991 • 24 citations

Endogenous insulin-like growth factor (IGF) binding proteins cause IGF-1 resistance in cultured fibroblasts from a patient with short stature.

1991 • 24 citations

Nutrition and Somatomedin: XXV. Regulation of Insulinlike Growth Factor Binding Protein 1 in Primary Cultures of Normal Rat Hepatocytes

1991 • 23 citations

Identification and regulation of insulin-like growth factor binding proteins produced by hormone-dependent and -independent human breast cancer cell lines

1991 • 23 citations

Characterization of insulin-like growth factor-binding proteins in rat serum, lymph, cerebrospinal and amniotic fluids, and in media conditioned by liver, bone and muscle cells

1990 • 23 citations

Focal Induction of IGF Binding Proteins in Proximal Tubules of Diabetic Rat Kidney

1992 • 23 citations

Identification and NH2-terminal amino acid sequence of three insulin-like growth factor-binding proteins in porcine serum

1991 • 22 citations

Characterization and cloning of a bovine insulin-like growth factor-binding protein

1990 • 21 citations

Mitogens Regulate the Production of Insulin-Like Growth Factor-Binding Protein by Swiss 3T3 Cells

1991 • 20 citations

Tissue-specific expression of insulin-like growth factor binding protein-3 protease activity during rat pregnancy

1992 • 20 citations

Anatomical relationships in the patterns of insulin-like growth factor (IGF)-I, IGF binding protein-1, and IGF-I receptor gene expression in the rat kidney

1992 • 20 citations

Production of the Rat Type 1 Insulin-Like Growth Factor-Binding Protein by Well Differentiated H4EIIC3 Hepatoma Cells: Identification, Purification, and N-Terminal Amino Acid Analysis*

1990 • 20 citations

Expression of messenger RNA for insulin-like growth factors and insulin-like growth factor binding proteins by experimental breast cancer and normal breast tissue in vivo.

1992 • 20 citations

Does the serum binding protein for growth hormone have a functional role?

1991 • 20 citations

Report on the nomenclature of the IGF binding proteins

1992 • 20 citations

Expression of hepatic insulin-like growth factor-I and insulin-like growth factor-binding protein-1 genes is transcriptionally regulated in streptozotocin-diabetic rats

1992 • 20 citations

Structure of the human insulin-like growth factor binding protein-2 gene

1992 • 19 citations

Regulation of Insulin-Like Growth Factor-Binding Protein Messenger Ribonucleic Acid Levels in Sheep Thyroid Cells*

1991 • 19 citations

Characterization of insulin-like growth factor-binding proteins secreted by isolated sheep thyroid epithelial cells

1990 • 19 citations

The gene for insulin-like growth factor-binding protein-1 is localized to human chromosomal region 7p14-p12

1990 • 18 citations

Rat ovarian insulin-like growth factor binding protein-3: a growth hormone-dependent theca-interstitial cell-derived antigonadotropin

1992 • 18 citations

Divergent effects of phorbol esters and insulin on insulin-like growth factor binding protein-1 (IGFBP-1) production and mRNA in rat H4IIe hepatoma cells

1992 • 17 citations

Not all insulin-like growth factor-binding proteins (IGFBPs) are detectable by western ligand blotting: case studies of PC12 pheochromocytoma and rat anterior pituitary IGFBPs and proteolyzed IGFBP-3.

1992 • 17 citations

Insulin-like growth factor (IGF)-I and IGF-II binding to an IGF binding protein. An investigation using chemical modification of tyrosine residues as a structural probe for the sites of interaction.

1991 • 17 citations

Thyrotropin Inhibits while Insulin, Epidermal Growth Factor and Tetradecanoyl Phorbol Acetate Stimulate Insulinlike Growth Factor Binding Protein Secretion from Sheep Thyroid Cells

1991 • 16 citations

Insulin-like growth factor binding protein expression in human small cell lung cancer cell lines

1991 • 16 citations

Transcription of the insulin-like growth factor-binding protein-2 gene is increased in neonatal and fasted adult rat liver

1992 • 15 citations

Expression of IGF-II, the IGF-II/Mannose-6-Phosphate Receptor and IGFBP-2 During Rat Embryogenesis

1991 • 14 citations

Lack of growth hormone effect on insulin-associated suppression of insulinlike growth factor binding protein 1 in humans

1990 • 14 citations

The Role of Insulin-Like Growth Factor Binding Proteins in Controlling the Expression of IGF Actions

1989 • 13 citations

Characterization of urinary insulin-like growth factor binding proteins

1992 • 12 citations

Human 'pregnancy-associated endometrial α1-globulin', a 32 kDa insulin-like growth factor-binding protein: immunohistological distribution and localization in the adult and fetus

1990 • 11 citations

Synthesis and regulation of insulin-like growth factor binding protein- 5 in FRTL-5 cells

1993 • 11 citations

Insulin-like growth factor binding protein (IGFBP)4 accounts for the connective tissue distribution of endothelial cell IGFBPs perfused through the isolated heart

1992 • 10 citations

Cytochalasin B stimulates insulin-like growth factor-binding protein-1 production by Hep G2 cells

1991 • 9 citations

Nutrition and somatomedin. XXV. Regulation of insulinlike growth factor binding protein 1 in primary cultures of normal rat hepatocytes

1991 • 8 citations

Not all insulin-like growth factor-binding proteins (IGFBPs) are detectable by western ligand blotting: case studies of PC12 pheochromocytoma and rat anterior pituitary IGFBPs and proteolyzed IGFBP-3

1992 • 6 citations

Focal induction of IGF binding proteins in proximal tubules of diabetic rat kidney

1992 • 6 citations

Expression of messenger RNA for insulin-like growth factors and insulin- like growth factor binding proteins by experimental breast cancer and normal breast tissue in vivo

1992 • 6 citations