Differential binding of fibroblast growth factor-2 and -7 to basement membrane heparan sulfate: comparison of normal and abnormal human tissues.

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

Structure and Biology of Proteoglycans

1988 • 707 citations

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

1994 • 665 citations

High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells

1987 • 653 citations

Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.

1992 • 634 citations

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

1992 • 625 citations

Large induction of keratinocyte growth factor expression in the dermis during wound healing.

1992 • 603 citations

The Degradation of Human Endothelial Cell-derived Perlecan and Release of Bound Basic Fibroblast Growth Factor by Stromelysin, Collagenase, Plasmin, and Heparanases

1996 • 601 citations

The Function of KGF in Morphogenesis of Epithelium and Reepithelialization of Wounds

1994 • 597 citations

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

1993 • 542 citations

Keratinocyte growth factor is required for hair development but not for wound healing.

1996 • 541 citations

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

1994 • 541 citations

The ins and outs of fibroblast growth factors

1994 • 535 citations

An Essential Heparin-Binding Domain in the Fibroblast Growth Factor Receptor Kinase

1993 • 520 citations

Developmental changes in heparan sulfate expression: in situ detection with mAbs.

1992 • 464 citations

CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor.

1995 • 434 citations

Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan

1993 • 420 citations

Identification of Six Novel Autophosphorylation Sites on Fibroblast Growth Factor Receptor 1 and Elucidation of Their Importance in Receptor Activation and Signal Transduction

1996 • 385 citations

The fibroblast growth factor family: Structural and biological properties

1989 • 362 citations

Differential Splicing in the Extracellular Region of Fibroblast Growth Factor Receptor 1 Generates Receptor Variants with Different Ligand-Binding Specificities

1992 • 321 citations

Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation.

1992 • 301 citations

Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain

1994 • 296 citations

Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican.

1996 • 273 citations

Mast cells and tumor angiogenesis

1976 • 267 citations

Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.

1993 • 263 citations

Expression of basic fibroblast growth factor in normal human tissues.

1990 • 258 citations

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

1994 • 239 citations

Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia.

1995 • 211 citations

Keratinocyte growth factor functions in epithelial induction during seminal vesicle development.

1994 • 187 citations

Progesterone-dependent expression of keratinocyte growth factor mRNA in stromal cells of the primate endometrium: keratinocyte growth factor as a progestomedin.

1994 • 182 citations

In situ detection of basic fibroblast growth factor by highly specific antibodies.

1990 • 168 citations

Inhibition of tumor metastasis by heparanase inhibiting species of heparin.

1994 • 167 citations

Heparin Is Required for Cell-Free Binding of Basic Fibroblast Growth Factor to a Soluble Receptor and for Mitogenesis in Whole Cells

1992 • 160 citations

Keratinocyte Growth Factor: A Fibroblast Growth Factor Family Member with Unusual Target Cell Specificity

1991 • 153 citations

Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis.

1994 • 139 citations

Macrophage and foam cell release of matrix-bound growth factors. Role of plasminogen activation

1993 • 137 citations

N-syndecan (syndecan 3) from neonatal rat brain binds basic fibroblast growth factor

1993 • 122 citations

Human cutaneous mast cells express basic fibroblast growth factor.

1995 • 119 citations

Keratinocyte growth factor is a growth factor for mammary epithelium in vivo. The mammary epithelium of lactating rats is resistant to the proliferative action of keratinocyte growth factor.

1994 • 111 citations

[11] Regulation by heparan sulfate in fibroblast growth factor signaling

1994 • 106 citations

Binding of heparin to basic fibroblast growth factor induces a conformational change

1992 • 103 citations

Basic fibroblast growth factor-syndecan complex at cell surface or immobilized to matrix promotes cell growth.

1992 • 90 citations

Heparan Sulfates Mediate the Binding of Basic Fibroblast Growth Factor to a Specific Receptor on Neural Precursor Cells

1995 • 89 citations

Immunolocalization of fibroblast growth factor receptor 1 and its ligands in human tissues.

1993 • 85 citations

Keratinocyte Growth Factor Inhibits Cross-linked Envelope Formation and Nucleosomal Fragmentation in Cultured Human Keratinocytes

1996 • 75 citations

Differential effect of cell-associated heparan sulfates on the binding of keratinocyte growth factor (KGF) and acidic fibroblast growth factor to the KGF receptor.

1994 • 75 citations

Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera.

1995 • 66 citations

Receptor Binding and Mitogenic Properties of Mouse Fibroblast Growth Factor 3

1995 • 59 citations

Co-localization of FGF-2 and a novel heparan sulphate proteoglycan in embryonic mouse brain

1994 • 30 citations

Structural requirements for inhibition of melanoma lung colonization by heparanase inhibiting species of heparin.

1995 • 20 citations