[11] Regulation by heparan sulfate in fibroblast growth factor signaling

A modified uronic acid carbazole reaction

1962 • 6,191 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Proteoglycans: Structures And Interactions

1991 • 1,596 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

The Fgf Family of Growth Factors and Oncogenes

1992 • 1,164 citations

Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans

1992 • 1,095 citations

Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes

1991 • 1,088 citations

Formation of anhydrosugars in the chemical depolymerization of heparin

1976 • 903 citations

Glycosaminoglycans and Their Binding to Biological Macromolecules

1978 • 835 citations

High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells

1987 • 653 citations

Multiple domains of the large fibroblast proteoglycan, versican.

1989 • 646 citations

Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.

1992 • 634 citations

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

1992 • 625 citations

Purification of a fibroblast growth factor from bovine pituitary.

1975 • 595 citations

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

1993 • 542 citations

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

1992 • 511 citations

Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor.

1993 • 449 citations

B lymphocytes express and lose syndecan at specific stages of differentiation.

1989 • 422 citations

Molecular Cloning of a Novel Cytokine cDNA Encoding the Ninth Member of the Fibroblast Growth Factor Family, which has a Unique Secretion Property

1993 • 390 citations

Three-Dimensional Structures of Acidic and Basic Fibroblast Growth Factors

1991 • 386 citations

Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein.

1992 • 346 citations

Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparan sulfate proteoglycan.

1986 • 342 citations

Purification of two distinct growth factors from bovine neural tissue by heparin affinity chromatography

1984 • 298 citations

The extended family of proteoglycans: social residents of the pericellular zone

1989 • 297 citations

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.

1990 • 292 citations

Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property.

1993 • 287 citations

Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts

1986 • 285 citations

Examination of the substrate specificity of heparin and heparan sulfate lyases

1990 • 265 citations

Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor.

1990 • 243 citations

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate.

1992 • 241 citations

Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen

1993 • 230 citations

Genetic analysis of proteoglycan structure, function and metabolism

1991 • 230 citations

Selective N-desulfation of heparin with dimethyl sulfoxide containing water or methanol

1976 • 211 citations

Structural characterization of the oligosaccharides formed by depolymerization of heparin with nitrous acid.

1985 • 194 citations

Chemically modified heparins as inhibitors of heparan sulfate specific endo-.beta.-glucuronidase (heparanase) of metastatic melanoma cells

1986 • 153 citations

Isolation and characterization of heparan sulfate proteoglycans produced by cloned rat microvascular endothelial cells.

1992 • 152 citations

Distribution of iduronate 2-sulphate residues in heparan sulphate. Evidence for an ordered polymeric structure

1991 • 150 citations

Biosynthesis of heparan sulfate on beta-D-xylosides depends on aglycone structure.

1994 • 137 citations

The coordinated regulation of heparan sulfate, syndecans and cell behavior

1993 • 129 citations

Novel regio- and stereoselective modifications of heparin in alkaline solution. Nuclear magnetic resonance spectroscopic evidence

1989 • 128 citations

Identification of a cysteine-rich receptor for fibroblast growth factors.

1992 • 124 citations

Modulation of cell surface heparan sulfate structure by growth of cells in the presence of chlorate

1989 • 110 citations

Molecular and cellular aspects of basement membranes

1994 • 109 citations

Molecular organization of heparan sulphate from human skin fibroblasts

1990 • 108 citations

Fibroblast growth factor receptor levels decrease during chick embryogenesis.

1990 • 99 citations

Presence in brain of a mitogenic agent promoting proliferation of myoblasts in low density culture

1975 • 93 citations

Adenosine triphosphate sulfurylase from Penicillium chrysogenum: Equilibrium binding, substrate hydrolysis, and isotope exchange studies

1978 • 81 citations

Reaction of unsaturated uronic acid residues with mercuric salts. Cleavage of the hyaluronic acid disaccharide 2-acetamido-2-deoxy-3-O-(β-<scp>d</scp>-gluco-4-enepyranosyluronic acid)-<scp>d</scp>-glucose

1987 • 81 citations

Biosynthesis of Heparin and Heparan Sulfatea

1989 • 77 citations

Heparan sulphate proteoglycans

1990 • 50 citations

Sequence analysis of heparan sulphate indicates defined location of N-sulphated glucosamine and iduronate 2-sulphate residues proximal to the protein-linkage region

1991 • 48 citations

Heparan sulphate: Functional role as a modulator of fibroblast growth factor activity

1993 • 47 citations

Syndecan: Regulator of Cell Morphology and Growth Factor Action at the Cell-matrix Interface.

1993 • 26 citations

Structural and Functional Diversity of the Heparan Sulfate Proteoglycans

1992 • 19 citations