Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Proteoglycans as modulators of growth factor activities

1991 • 1,338 citations

Structural Characterization and Biological Functions of Fibroblast Growth Factor

1987 • 1,299 citations

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

1991 • 1,135 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Proteoglycans in Cell Regulation

1989 • 691 citations

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

1988 • 687 citations

High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells

1987 • 653 citations

Angiogenesis Inhibition and Tumor Regression Caused by Heparin or a Heparin Fragment in the Presence of Cortisone

1983 • 622 citations

Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules

1989 • 597 citations

Structure and function of heparan sulphate proteoglycans

1986 • 485 citations

A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization

1989 • 370 citations

Cell Surface Receptors: A Short Course on Theory and Methods

1996 • 351 citations

Receptor- and heparin-binding domains of basic fibroblast growth factor.

1988 • 318 citations

The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains.

1991 • 297 citations

Three-dimensional structure of human basic fibroblast growth factor.

1991 • 285 citations

Metabolism of receptor-bound and matrix-bound basic fibroblast growth factor by bovine capillary endothelial cells.

1988 • 276 citations

Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.

1990 • 274 citations

Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides

1985 • 243 citations

A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin.

1991 • 236 citations

Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor.

1991 • 221 citations

The affinity of fibroblast growth factors (FGFs) for heparin; FGF-heparan sulfate interactions in cells and extracellular matrix

1990 • 177 citations

Heparin sequences in the heparan sulfate chains of an endothelial cell proteoglycan.

1987 • 161 citations

Distribution of iduronate 2-sulphate residues in heparan sulphate. Evidence for an ordered polymeric structure

1991 • 150 citations

Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.

1986 • 123 citations

Epidermal growth factor (EGF) induces oligomerization of soluble, extracellular, ligand-binding domain of EGF receptor. A low resolution projection structure of the ligand-binding domain

1991 • 105 citations

Production, biological activity, and structure of recombinant basic fibroblast growth factor and an analog with cysteine replaced by serine.

1988 • 100 citations

Isolation of a Receptor for Acidic and Basic Fibroblast Growth Factor from Embryonic Chick

1989 • 88 citations

Importance of Size, Sulfation, and Anticoagulant Activity in the Potentiation of Acidic Fibroblast Growth Factor by Heparin

1989 • 76 citations

Transfer of functional EGF receptors to an IL3‐dependent cell line

1988 • 53 citations

Identification of Receptors Using Direct Radioligand Binding Techniques

1986 • 33 citations