Growth Factor Inducible Genes in Fibroblasts

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Catalog of chromosome aberrations in cancer

1985 • 1,522 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

CELL SURFACE INTERACTIONS WITH EXTRACELLULAR MATERIALS

1983 • 1,147 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

The locomotion of fibroblasts in culture

1971 • 955 citations

γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

1985 • 949 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

1988 • 733 citations

Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7.

1986 • 704 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

Common DNA binding site for Fos protein complexesand transcription factor AP-1

1988 • 613 citations

Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

1985 • 589 citations

Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.

1988 • 580 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

1989 • 572 citations

The Fos Complex and Fos-Related Antigens Recognize Sequence Elements That Co ntain AP-1 Binding Sites

1988 • 532 citations

A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily.

1988 • 532 citations

Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos

1987 • 523 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Distribution of Fibronectin During Wound Healing in Vivo

1981 • 474 citations

jun-D: a third member of the jun gene family.

1989 • 469 citations

Avian sarcoma virus 17 carries the jun oncogene.

1987 • 445 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

Induction of protooncogene c-jun by serum growth factors.

1988 • 438 citations

A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

1988 • 428 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor.

1986 • 386 citations

Cytogenetic features of human neuroblastomas and cell lines.

1981 • 386 citations

Fibronectin and wound healing

1984 • 379 citations

Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant.

1987 • 360 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

Saturation Mutagenesis of the Yeast his3 Regulatory Site: Requirements for Transcriptional Induction and for Binding by GCN4 Activator Protein

1986 • 352 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

The 5q− anomaly

1985 • 330 citations

Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion.

1985 • 322 citations

The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

1989 • 318 citations

Amino acid sequence of human platelet factor 4.

1977 • 318 citations

Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.

1988 • 301 citations

Role of fibronectin in collagen deposition: Fab' to the gelatin-binding domain of fibronectin inhibits both fibronectin and collagen organization in fibroblast extracellular matrix.

1982 • 298 citations

A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens.

1987 • 292 citations

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

1989 • 286 citations

Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells.

1987 • 283 citations

Tropomyosin antibody: the specific localization of tropomyosin in nonmuscle cells.

1975 • 280 citations

Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.

1987 • 279 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene.

1989 • 252 citations

Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA.

1987 • 251 citations

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein.

1985 • 249 citations

Possible positive autocrine feedback in the prereplicative phase of human fibroblasts

1987 • 234 citations

Temporal and spatial regulation of fibronectin in early Xenopus development

1984 • 232 citations

Structure and chromosomal localization of the functional intronless human JUN protooncogene.

1988 • 221 citations

Complete covalent structure of human .beta.-thromboglobulin

1978 • 215 citations

Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein

1987 • 206 citations

Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice

1985 • 200 citations

Human tissue factor: cDNA sequence and chromosome localization of the gene

1987 • 189 citations

Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor.

1983 • 181 citations

Two different factors bind to the alpha-domain of the polyoma virus enhancer, one of which also interacts with the SV40 and c-fos enhancers.

1987 • 179 citations

Mapping functional regions of transcription factor TFIIIA.

1988 • 178 citations

Characterization of cellular proteins recognizing the HIV enhancer using a microscale DNA-affinity precipitation assay

1987 • 176 citations

Tissue-specific expression of c-jun and junB during organogenesis in the mouse

1989 • 172 citations

Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos.

1989 • 155 citations

Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene.

1988 • 147 citations

Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

1989 • 147 citations

Purification of melanoma growth stimulatory activity

1986 • 130 citations

Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.

1987 • 129 citations

Xenopus laevis integrins. Structural conservation and evolutionary divergence of integrin beta subunits.

1988 • 126 citations

Characterization of human platelet basic protein, a precursor form of low-affinity platelet factor 4 and .beta.-thromboglobulin

1986 • 123 citations

Clinical characteristics and prognosis of 50 patients with a myeloproliferative syndrome and deletion of part of the long arm of chromosome 5

1985 • 93 citations

Cloning and characterization of a novel T cell activation gene.

1987 • 88 citations

Structure-function analysis of fos protein: A single amino acid change activates the immortalizing potential of v-fos

1987 • 81 citations

Coordinate induction of fibronectin, fibronectin receptor, tropomyosin, and actin genes in serum-stimulated fibroblasts

1989 • 74 citations

The Structure and Function of Steroid Receptor Protein

1989 • 70 citations

Structure, chromosome mapping and regulation of the mouse zinc-finger gene Krox-24; evidence for a common regulatory pathway for immediate-early serum-response genes

1989 • 67 citations

Structure and chromosomal localization of the function intronless human JUN protooncogene

1988 • 62 citations

Localization of the human JUN protooncogene to chromosome region 1p31-32.

1988 • 61 citations

Molecular cloning of gene sequences regulated by tumor promoters and mitogens through protein kinase C.

1987 • 55 citations

Cloning and sequence of a secretory protein induced by growth factors in mouse fibroblasts

1989 • 41 citations

Expression, cloning and cDNA sequence of a fibroblast serum-regulated gene encoding a putative actin-associated protein (p27)

1989 • 41 citations

Isolation and structural analysis of a biologically active chicken c-fos cDNA: identification of evolutionarily conserved domains in fos protein.

1987 • 32 citations

Steroid hormone receptors and oncogenes.

1988 • 12 citations

Specific antibody against a protein (p27) present in nonestablished fibroblasts. A putative microfilament-associated protein

1987 • 8 citations