Purification of melanoma growth stimulatory activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin.

1978 • 1,530 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Methods for growth of cultured cells in serum-free medium

1980 • 1,013 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1984 • 666 citations

Purification of human platelet-derived growth factor.

1979 • 586 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma

1981 • 492 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

Platelet-derived growth factor: purification and partial characterization.

1979 • 436 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Cellular transformation by coordinated action of three peptide growth factors from human platelets

1984 • 383 citations

Human platelet-derived growth factor. Purification and resolution into two active protein fractions.

1981 • 353 citations

Expression of insulin-like growth factor-II transcripts in Wilms' tumour

1985 • 352 citations

Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines.

1985 • 344 citations

Human transforming growth factor. Production by a melanoma cell line, purification, and initial characterization.

1982 • 223 citations

Computer-based characterization of epidermal growth factor precursor

1984 • 212 citations

Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets.

1984 • 212 citations

Growth factors produced by sarcoma virus-transformed cells.

1978 • 191 citations

Chemical and biological properties of a growth factor from human‐cultured osteosarcoma cells: Resemblance with platelet‐derived growth factor

1980 • 188 citations

The growth of mouse melanoma cells in hormone-supplemented, serum-free medium

1979 • 143 citations

Connective tissue activation

1980 • 142 citations

Stimulation by insulin-like growth factors is required for cellular transformation by type beta transforming growth factor.

1985 • 137 citations

Human interleukin 1. Purification to homogeneity.

1985 • 107 citations

Cellular responsiveness to growth factors correlates with a cell's ability to express the transformed phenotype

1983 • 100 citations

Characterization of autostimulatory and transforming growth factors from human melanoma cells.

1985 • 99 citations

Growth Regulation of Human Melanocytes: Mitogenic Factors in Extracts of Melanoma, Astrocytoma, and Fibroblast Cell Lines

1985 • 95 citations

Epithelial tissue-derived growth factor-like polypeptides.

1983 • 85 citations

Growth Factor and Cytogenetic Abnormalities in Cultured Nevi and Malignant Melanomas

1986 • 78 citations

Extraction of a melanoma growth-stimulatory activity from culture medium conditioned by the Hs0294 human melanoma cell line.

1983 • 73 citations

Evidence that a human osteosarcoma cell line which secretes a mitogen similar to platelet-derived growth factor requires growth factors present in platelet-poor plasma.

1983 • 73 citations

Platelet-derived growth factor agonist activity of a secreted form of the v-sis oncogene product.

1985 • 72 citations

Adrenocortical Carcinoma and Hypoglycemia: Evidence for Production of Nonsuppressible Insulin-Like Activity by the Tumor

1977 • 69 citations

Autocrine and paracrine growth stimulation of cells derived from human skin

1983 • 68 citations

Connective tissue activation

1979 • 66 citations

A PLATELET‐DERIVED GROWTH FACTOR ANALOG PRODUCED BY A HUMAN CLONAL GLIOMA CELL LINE*

1982 • 62 citations

Biosynthesis of rat insulin-like growth factor II. I. Immunochemical demonstration of a approximately 20-kilodalton biosynthetic precursor of rat insulin-like growth factor II in metabolically labeled BRL-3A rat liver cells.

1985 • 62 citations

Ectopic peptides released by a human melanoma cell line that modulate the transformed phenotype.

1985 • 47 citations

Production of an insulin-like growth factor by osteosarcoma

1984 • 46 citations

Neuroblastoma cells produce transforming growth factors during exponential growth in a defined hormone-free medium.

1984 • 45 citations

Inability of anti-epidermal growth factor receptor monoclonal antibody to block “autocrine” growth stimulation in transforming growth factor-secreting melanoma cells.

1984 • 44 citations

Human melanoma cells have both nerve growth factor and nerve growth factor-specific receptors on their cell surfaces.

1979 • 41 citations

Detection of High Molecular Weight Forms of Platelet-Derived Growth Factor by Sequence-Specific Antisera

1984 • 36 citations

In vitro growth promotion in human malignant melanoma cells by fibroblast growth factor.

1982 • 17 citations

Transforming growth factors released from Kirsten sarcoma virus transformed cells do not compete for epidermal growth factor membrane receptors

1983 • 14 citations

Synthesis of [3,5-125I]triiodo-l-thyronine of high specific activity

1980 • 13 citations