The Structure and Function of Steroid Receptor Protein

Personal communication

1989 • 2,984 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Sequence and Expression of Human Estrogen Receptor Complementary DNA

1986 • 1,321 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

Nuclear localization of unoccupied oestrogen receptors

1984 • 882 citations

Identification of a new class of steroid hormone receptors

1988 • 845 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors.

1986 • 733 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

1986 • 722 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Monoclonal antibodies to human estrogen receptor.

1980 • 545 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Molecular Cloning of Complementary DNA Encoding the Avian Receptor for Vitamin D

1987 • 516 citations

Molecular cloning and charcterization of rat estrogen receptor cDNA

1987 • 488 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

1984 • 449 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

1984 • 442 citations

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1987 • 434 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

Biochemistry, Molecular Biology, and Physiology of the Glucocorticoid Receptor*

1987 • 409 citations

The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins.

1986 • 392 citations

In vivo protein–DNA interactions in a glucocorticoid response element require the presence of the hormone

1986 • 328 citations

On the antiquity of introns

1986 • 324 citations

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

1987 • 299 citations

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

1987 • 282 citations

Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding

1984 • 281 citations

Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

1984 • 278 citations

Glucocorticoid Receptor Mutants That Define a Small Region Sufficient for Enhancer Activation

1987 • 260 citations

The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function.

1988 • 246 citations

Molecular Cloning of the Chicken Progesterone Receptor

1986 • 243 citations

The Metabolic Code

1975 • 231 citations

Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone.

1987 • 229 citations

The glucocorticoid domain: Steroid-mediated changes in the rate of synthesis of rat hepatoma proteins

1978 • 227 citations

The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor.

1985 • 215 citations

Cloning and sequence analysis of rabbit progesterone-receptor complementary DNA.

1986 • 204 citations

Genetic Approaches to Steroid Hormone Action

1976 • 203 citations

Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.

1984 • 202 citations

A multigene family encoding several “finger” structures is present and differentially active in mammalian genomes

1987 • 197 citations

Monoclonal antibodies against the rat liver glucocorticoid receptor.

1984 • 188 citations

Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

1984 • 186 citations

Steroid-free glucocorticoid receptor binds specifically to mouse mammary tumour virus DNA

1986 • 185 citations

Sequence-specific DNA binding of the progesterone receptor to the uteroglobin gene: effects of hormone, antihormone and receptor phosphorylation.

1986 • 184 citations

Antiglucocorticosteroid effects suggest why steroid hormone is required for receptors to bind DNA in vivo but not in vitro

1987 • 179 citations

Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

1982 • 178 citations

Cloning of the chicken progesterone receptor.

1986 • 177 citations

TheXenopus laevisEstrogen Receptor: Sequence Homology with Human and Avian Receptors and Identification of Multiple Estrogen Receptor Messenger Ribonucleic Acids*

1987 • 159 citations

Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells.

1985 • 147 citations

Androgen regulation by the long terminal repeat of mouse mammary tumor virus.

1986 • 138 citations

Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.

1987 • 125 citations

Identification of hormone-interacting amino acid residues within the steroid-binding domain of the glucocorticoid receptor in relation to other steroid hormone receptors.

1988 • 121 citations

Monoclonal antibodies to the rat liver glucocorticoid receptor.

1982 • 113 citations

Sequence specificity in transcription and translation

1985 • 113 citations

Species-specific rDNA transcription is due to promoter-specific binding factors.

1984 • 108 citations

Structural Organization and Regulation of the Chicken Estrogen Receptor

1987 • 104 citations

Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter.

1986 • 97 citations

Glucocorticoid receptors lacking hormone-binding activity are bound in nuclei of ATP-depleted cells

1986 • 95 citations

Thyroid hormone nuclear receptor. Evidence for multimeric organization in chromatin.

1982 • 91 citations

Cloning of the human glucocorticoid receptor cDNA

1985 • 79 citations

An antiserum to the rat liver glucocorticoid receptor.

1980 • 63 citations

Antibodies to rabbit progesterone receptor: crossreaction with human receptor.

1981 • 61 citations

Androgen-regulated expression of a cloned rat prostatic C3 gene transfected into mouse mammary tumor cells

1983 • 57 citations

Biochemical actions of hormones

1987 • 54 citations

The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones.

1987 • 52 citations

Glucocorticoid receptors bound to the antagonist RU486 are not downregulated despite their capacity to interact in vitro with defined gene regions

1987 • 47 citations

Phosphorylation of L-cell glucocorticoid receptors in immune complexes: evidence that the receptor is not a protein kinase

1986 • 33 citations

Genetic and Epigenetic Bases of Glucocorticoid Resistance in Lymphoid Cell Lines

1985 • 31 citations

Dexamethasone inhibits α-fetoprotein gene transcription in neonatal rat liver and isolated nuclei

1985 • 27 citations

Cell Genetics of Glucocorticoid Responsiveness

1980 • 25 citations

AQUEOUS TWO-PHASE PARTITIONING FOR THE STUDY OF STEROID RECEPTOR ACTIVATION

1987 • 4 citations

Steroid hormone action

1987 • 2 citations