Involvement of Fas-Mediated Apoptosis in the Hematopoietic Progenitor Cells of Graft-Versus-Host Reaction-Associated Myelosuppression

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 617 citations

Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease.

1987 • 609 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 565 citations

Induction of Graft-versus-Host Disease as Immunotherapy for Relapsed Chronic Myeloid Leukemia

1994 • 510 citations

Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

1995 • 505 citations

Allogeneic cell therapy with donor peripheral blood cells and recombinant human interleukin-2 to treat leukemia relapse after allogeneic bone marrow transplantation

1996 • 439 citations

Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity.

1994 • 386 citations

Erythropoietin for the Treatment of Porphyria Cutanea Tarda in a Patient on Long-Term Hemodialysis

1990 • 369 citations

Transfusion-Associated Graft-versus-Host Disease

1990 • 347 citations

Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule

1991 • 331 citations

Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease.

1996 • 310 citations

The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice.

1996 • 303 citations

A systemic lupus erythematosus (SLE)‐like disease in mice induced by abnormal T‐B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1982 • 267 citations

Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8+ T cells.

1995 • 232 citations

Polymorphism of murine Fas ligand that affects the biological activity

1997 • 201 citations

Differential cytokine expression in acute and chronic murine graft‐versus‐host‐disease

1993 • 194 citations

Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells

1995 • 188 citations

Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease.

1987 • 169 citations

Involvement of Fas-Mediated Apoptosis in the Inhibitory Effects of Interferon-α in Chronic Myelogenous Leukemia

1997 • 152 citations

Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells

1995 • 149 citations

Hematopoietic stem cells are not direct cytotoxic targets of natural killer cells

1996 • 77 citations

Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes.

1991 • 69 citations

Suppressor T Cells Arising in Mice Undergoing a Graft-vs-Host Response

1977 • 69 citations

Profound atrophy of the bone marrow reflecting major histocompatibility complex class II-restricted destruction of stem cells by CD4+ cells.

1994 • 60 citations

Graft-versus-host effect after allogeneic hematopoietic stem cell transplantation: GVHD and GVL

1996 • 53 citations

Characterization of T-Cell Clones Derived From Peripheral Blood Lymphocytes of a Patient With Transfusion-Associated Graft-Versus-Host Disease: Fas-Mediated Killing by CD4+ and CD8+ Cytotoxic T-Cell Clones and Tumor Necrosis Factor β Production by CD4+ T-Cell Clones

1997 • 50 citations

Fas-Mediated Apoptosis of the Hematopoietic Progenitor Cells in Mice Infected With Murine Cytomegalovirus

1997 • 40 citations

Immunopathogenic Mechanisms of Posttransfusion Graft-vs-Host Disease

1993 • 39 citations

Fas-Mediated Apoptosis of the Hematopoietic Progenitor Cells in Mice Infected With Murine Cytomegalovirus

1997 • 36 citations

GVHR elicited by products of class I or class II loci of the MHC: analysis of the response of mouse T lymphocytes to products of class I and class II loci of the MHC in correlation with GVHR-induced mortality, medullary aplasia, and enteropathy.

1985 • 34 citations

Graft-Versus-Host Disease in Experimental Allogeneic Bone Marrow Transplantation

1991 • 30 citations

Major histocompatibility complex class II-mediated inhibition of hematopoiesis in long-term marrow cultures involves apoptosis and is prevented by c-kit ligand [see comments]

1995 • 25 citations

Graft-versus-Host Disease in Bone Marrow Transplantation: Experimental, Laboratory, and Clinical Contributions of the Last Few Years

1993 • 21 citations

The Therapeutic Effect of Interleukin‐12 or Its Antagonist in Transplantation Immunity

1996 • 12 citations