Hematopoietic stem cells are not direct cytotoxic targets of natural killer cells

Biology of Natural Killer Cells

1989 • 2,970 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells

1992 • 805 citations

Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

1993 • 341 citations

Natural Immunity: A T‐Cell‐Independent Pathway of Macrophage Activation, Defined in the scid Mouse

1991 • 321 citations

Do Natural Killer Cells Engage in Regulated Reactions Against Self to Ensure Homeostasis?

1979 • 287 citations

Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection.

1987 • 242 citations

Biology and Genetics of Hybrid Resistance

1987 • 191 citations

A natural killer cell receptor specific for a major histocompatibility complex class I molecule.

1994 • 157 citations

Heterogeneity of hematopoietic stem cells

1993 • 139 citations

The role of granzyme B in murine models of acute graft-versus-host disease and graft rejection

1996 • 138 citations

Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment.

1996 • 124 citations

Host MHC class I molecules modulate in vivo expression of a NK cell receptor.

1994 • 119 citations

Cloning and characterization of 5E6(Ly-49C), a receptor molecule expressed on a subset of murine natural killer cells.

1995 • 96 citations

Perforin- and Fas-mediated cytotoxic pathways are not required for allogeneic resistance to bone marrow grafts in mice.

1995 • 52 citations

Murine Natural Killer Cells And Marrow Graft Rejection

1992 • 18 citations

[5] Somatic cell genetic analysis of myelomas and hybridomas

1987 • 15 citations

Allogeneic Bone Marrow Transplantation

1983 • 14 citations

Transgenic mice carrying the diphtheria toxin A chain gene under the control of the granzyme A promoter: expected depletion of cytotoxic cells and unexpected depletion of CD8 T cells.

1995 • 13 citations

Anti-asialo GM1 antiserum treatment of lethally irradiated recipients before bone marrow transplantation: evidence that recipient natural killer depletion enhances survival, engraftment, and hematopoietic recovery

1990 • 4 citations