Polymorphism of murine Fas ligand that affects the biological activity

The Fas Death Factor

1995 • 4,070 citations

The expanding universe of T-cell subsets: Th1, Th2 and more

1996 • 3,710 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

1996 • 1,281 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

1995 • 1,120 citations

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

1993 • 1,073 citations

Lymphocyte apoptosis induced by CD95 (APO–1/Fas) ligand–expressing tumor cells — A mechanism of immune evasion?

1996 • 917 citations

Metalloproteinase-mediated release of human Fas ligand.

1995 • 835 citations

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity.

1993 • 801 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Structure of tumour necrosis factor

1989 • 512 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

The mouse fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

1994 • 335 citations

Antitumor effect of locally produced CD95 ligand

1997 • 315 citations

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1994 • 307 citations

Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.

1994 • 294 citations

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation.

1993 • 261 citations

CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.

1992 • 220 citations

The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.

1993 • 210 citations

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody.

1995 • 197 citations

Fas‐based lymphocyte‐mediated cytotoxicity against syngeneic activated lymphocytes: A regulatory pathway?

1994 • 157 citations

Expression and function of mouse Fas antigen on immature and mature T cells.

1995 • 133 citations

Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis.

1991 • 110 citations

Fas‐mediated Cytotoxicity ‐ A New Immunoregulatory and Pathogenic Function of Thl CD4⁺ T Cells

1995 • 71 citations

Comparative molecular modelling of the Fas-ligand and other members of the TNF family

1995 • 67 citations

Characterization of the non-functional Fas ligand of gld mice

1995 • 67 citations

Contribution of Fas ligand to cardiac allograft rejection

1996 • 61 citations

A secreted form of the human lymphocyte cell surface molecule CD8 arises from alternative splicing.

1989 • 52 citations

Aspartic acid 50 and tyrosine 108 are essential for receptor binding and cytotoxic activity of tumour necrosis factor beta (lymphotoxin)

1991 • 45 citations

Structural and functional domains in human tumour necrosis factors

1991 • 37 citations