Cadherin junctions in mammary tumors.

Wnt signaling: a common theme in animal development

1997 • 2,579 citations

A causal role for E-cadherin in the transition from adenoma to carcinoma

1998 • 1,415 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Exogenous Expression of N-Cadherin in Breast Cancer Cells Induces Cell Migration, Invasion, and Metastasis

2000 • 913 citations

β-catenin signaling and cancer

1999 • 867 citations

N-Cadherin Promotes Motility in Human Breast Cancer Cells Regardless of Their E-Cadherin Expression

1999 • 773 citations

Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways

1999 • 699 citations

Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis.

1993 • 658 citations

Mutations of the human E-cadherin (CDH1) gene

1998 • 598 citations

P120 Catenin Regulates the Actin Cytoskeleton via Rho Family Gtpases

2000 • 563 citations

NEURAL CELL ADHESION MOLECULES OF THE IMMUNOGLOBULIN SUPERFAMILY: Role in Axon Growth and Guidance

1997 • 473 citations

Inhibition of RhoA by p120 catenin

2000 • 459 citations

Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas.

1993 • 457 citations

Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion

2000 • 456 citations

Mammary ductal elongation: Differentiation of myoepithelium and basal lamina during branching morphogenesis

1983 • 453 citations

Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma.

1993 • 398 citations

Methylation Patterns of the E-cadherin 5′ CpG Island Are Unstable and Reflect the Dynamic, Heterogeneous Loss of E-cadherin Expression during Metastatic Progression

2000 • 387 citations

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis

1997 • 341 citations

Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.

1996 • 328 citations

Tyrosine phosphorylation and cadherin/catenin function

1997 • 318 citations

Reduced E-Cadherin Expression is Associated With Invasiveness and Unfavorable Prognosis in Breast Cancer

1996 • 302 citations

Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinomain situ

1997 • 299 citations

Diffuse Type Gastric and Lobular Breast Carcinoma in a Familial Gastric Cancer Patient with an E-Cadherin Germline Mutation

1999 • 294 citations

Cadherins and catenins: role in signal transduction and tumor progression.

1999 • 290 citations

Characterization of the interactions of α-catenin with α-actinin and β-catenin/plakoglobin

1997 • 260 citations

Cadherin-11 is expressed in invasive breast cancer cell lines.

1999 • 235 citations

N-Cadherin Promotes Adhesion Between Invasive Breast Cancer Cells and the Stroma

1997 • 229 citations

p120ctn Acts as an Inhibitory Regulator of Cadherin Function in Colon Carcinoma Cells

1999 • 229 citations

H–cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer

1996 • 214 citations

Re-expression of E-cadherin, ?-catenin and ?-catenin, but not of ?-catenin, in metastatic tissue from breast cancer patients

2000 • 206 citations

N-Cadherin Extracellular Repeat 4 Mediates Epithelial to Mesenchymal Transition and Increased Motility

2000 • 201 citations

Epithelial (E‐) and placentae (P‐) cadherin cell adhesion molecule expression in breast carcinoma

1993 • 200 citations

The Role of the E-Cadherin/Catenin Adhesion Complex in the Development and Progression of Cancer

1999 • 195 citations

E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model.

1996 • 193 citations

Functional Cis-Heterodimers of N- and R-Cadherins

2000 • 189 citations

E-cadherin and α-, β-, and γ-catenin protein expression in relation to metastasis in human breast carcinoma

1998 • 185 citations

Protein tyrosine phosphatases as adhesion receptors

1995 • 182 citations

Soluble E-cadherin fragments increased in circulation of cancer patients

1994 • 178 citations

p120ctn Binds to the Membrane-proximal Region of the E-cadherin Cytoplasmic Domain and Is Involved in Modulation of Adhesion Activity

1999 • 171 citations

Separating favorable from unfavorable prognostic markers in breast cancer: the role of E-cadherin.

2000 • 170 citations

Anomalous expression of P-cadherin in breast carcinoma. Correlation with E-cadherin expression and pathological features.

1995 • 165 citations

Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells.

1994 • 165 citations

P-cadherin expression in breast carcinoma indicates poor survival

1999 • 149 citations

Mechanisms of inactivation of E-cadherin in breast cancer cell lines.

1998 • 148 citations

Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo.

1995 • 147 citations

Expression of E‐cadherin (E‐CD) as related to other prognostic factors and survival in breast cancer

1994 • 132 citations

The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas

1995 • 123 citations

Role of morphogenetic factors in metastasis of mammary carcinoma cells

1998 • 122 citations

Reduced alpha-catenin and E-cadherin expression in breast cancer.

1995 • 117 citations

E-cadherin downregulation in cancer: fuel on the fire?

1999 • 115 citations

Tamoxifen restores the E-cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype.

1994 • 115 citations

Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins: Identification of unique and shared domains

1996 • 108 citations

An immunohistochemical examination of the expression of E-cadherin, ?- and ?/?-catenins, and ?2- and ?1-integrins in invasive breast cancer

1999 • 99 citations

Altered expression of E-cadherin in breast cancer

2000 • 97 citations

Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro

1993 • 96 citations

Expression of E-cadherin and catenins in invasive mammary carcinomas.

1997 • 93 citations

Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer

1999 • 93 citations

Expression of β‐catenin in normal breast tissue and breast carcinoma: a comparative study with epithelial cadherin and α‐catenin

1996 • 91 citations

A role for cadherins in cellular signaling and differentiation

1998 • 88 citations

Localization of Human Cadherin Genes to Chromosome Regions Exhibiting Cancer-Related Loss of Heterozygosity

1998 • 85 citations

Defects in the Regulation of β-Catenin in Colorectal Cancer

1999 • 82 citations

Comparative analyses of bone marrow micrometastases in breast and gastric cancer

1996 • 75 citations

E-cadherin relates to EGFR expression and lymph node metastasis in primary breast carcinoma

1996 • 74 citations

Reduced E-Cadherin Immunohistochemical Expression in Node-Negative Breast Carcinomas Correlates With 10-Year Survival

1998 • 70 citations

H-cadherin expression inhibits in vitro invasiveness and tumor formation in vivo

1998 • 68 citations

E-Cadherin (E-cad) expression in duct carcinoma in situ (DCIS) of the breast

1997 • 63 citations

Stimulation of Cell Invasion and Migration by Alcohol in Breast Cancer Cells

2000 • 59 citations

E-cadherin quantititive immunocytochemical assays in breast carcinomas

1997 • 55 citations

The biological and prognostic significance of cell polarity and E-cadherin in grade I infiltrating ductal carcinoma of the breast

1999 • 50 citations

E-cadherin and catenins: Molecules with versatile roles in normal and neoplastic epithelial cell biology

1998 • 43 citations

Modulation of E‐cadherin expression and morphological phenotype in the intravascular component of adenocarcinomas

1995 • 40 citations

E- and P-cadherin expression in tumor tissues and soluble E-cadherin levels in sera of patients with skin cancer

1996 • 37 citations

P‐cadherin expression in breast carcinoma indicates poor survival

1999 • 29 citations

Adriamycin activates E-cadherin-mediated cell-cell adhesion in human breast cancer cells.

1999 • 21 citations

Lack of correlation between serum levels of E- and P-cadherin fragments and the presence of breast cancer

2000 • 21 citations

Assay of E-cadherin by ELISA in human breast cancers

1997 • 19 citations

Cadherins, steroids and cancer

1995 • 18 citations

Deleted Work

1955 • 0 citations