Protein tyrosine phosphatases as adhesion receptors

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.

1993 • 912 citations

CD45: An Emerging Role as a Protein Tyrosine Phosphatase Required for Lymphocyte Activation and Development

1994 • 733 citations

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

1995 • 704 citations

Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts.

1992 • 519 citations

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1993 • 447 citations

Tyrosine Phosphorylation of β-Catenin and Plakoglobin Enhanced by Hepatocyte Growth Factor and Epidermal Growth Factor in Human Carcinoma Cells

1994 • 421 citations

Two contrary functions of tenascin: Dissection of the active sites by recombinant tenascin fragments

1989 • 415 citations

The carbonic anhydrase domain of receptor tyrosine phosphatase β is a functional ligand for the axonal cell recognition molecule contactin

1995 • 397 citations

Molecular linkage between cadherins and actin filaments in cell—cell adherens junctions

1992 • 359 citations

The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

1995 • 329 citations

Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules.

1994 • 322 citations

Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo.

1995 • 313 citations

The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions.

1992 • 312 citations

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia.

1995 • 304 citations

Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase.

1994 • 291 citations

Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation

1993 • 268 citations

Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue.

1994 • 255 citations

CD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin.

1993 • 243 citations

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

1993 • 227 citations

The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors

1991 • 224 citations

Receptor tyrosine phosphatase R-PTP-kappa mediates homophilic binding.

1994 • 224 citations

Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density.

1994 • 222 citations

Fibronectin structure and assembly

1994 • 211 citations

The Receptor Tyrosine Kinase ARK Mediates Cell Aggregation by Homophilic Binding

1995 • 179 citations

Receptor tyrosine phosphatase beta is expressed in the form of proteoglycan and binds to the extracellular matrix protein tenascin.

1994 • 179 citations

Focal adhesion kinase: an integrin-linked protein tyrosine kinase

1993 • 177 citations

An adhesive domain detected in functionally diverse receptors

1993 • 168 citations

Expression of the receptor-linked protein tyrosine phosphatase LAR: proteolytic cleavage and shedding of the CAM-like extracellular region.

1992 • 166 citations

Homophilic Interactions Mediated by Receptor Tyrosine Phosphatases μ and κ. A CRITICAL ROLE FOR THE NOVEL EXTRACELLULAR MAM DOMAIN

1995 • 156 citations

Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM.

1992 • 145 citations

Cloning and Characterization of R-PTP-κ, a New Member of the Receptor Protein Tyrosine Phosphatase Family with a Proteolytically Cleaved Cellular Adhesion Molecule-Like Extracellular Region

1993 • 128 citations

Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate

1994 • 115 citations

Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu.

1994 • 112 citations

Multiple receptor‐like protein tyrosine phosphatases in the form of chondroitin sulfate proteoglycan

1994 • 100 citations

Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.

1994 • 98 citations

The expression of a novel receptor-type tyrosine phosphatase suggests a role in morphogenesis and plasticity of the nervous system

1993 • 96 citations

Regulation of CD45 engagement by the B-cell receptor CD22.

1995 • 91 citations

Elevation of membrane tyrosine phosphatase activity in density-dependent growth-arrested fibroblasts.

1991 • 87 citations

The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits.

1992 • 84 citations

Unraveling the cytoplasmic interactions of the cadherin superfamily.

1994 • 77 citations

Controlled induction of focal adhesion disassembly and migration in primary fibroblasts

1993 • 76 citations

Evidence that peritoneal exudate cells cultured with eye-derived fluids are the proximate antigen-presenting cells in immune deviation of the ocular type.

1993 • 71 citations

Not just glue: cell-cell junctions as cellular signaling centers

1995 • 68 citations

Brain-specific receptor-type protein-tyrosine phosphatase RPTP beta is a chondroitin sulfate proteoglycan in vivo.

1994 • 50 citations

Engagement of the common leukocyte antigen CD45 induces homotypic adhesion of activated human T cells.

1994 • 47 citations

Regulation of the tyrosine kinase-dependent adhesion pathway in human lymphocytes through CD45.

1993 • 46 citations

The phosphotyrosine phosphatase inhibitor vanadyl hydroperoxide induces morphological alterations, cytoskeletal rearrangements and increased adhesiveness in rat neutrophil leucocytes

1993 • 45 citations

Engagement of the CD45 molecule induces homotypic adhesion of human thymocytes through a LFA-1/ICAM-3-dependent pathway.

1994 • 38 citations

Protein Tyrosine Phosphatases: The Problems of a Growing Family

1992 • 35 citations

Structural diversity of eukaryotic protein tyrosine phosphatases: functional and evolutionary implications

1993 • 32 citations

An adhesion molecule-like protein that interacts with and is a substrate for a Drosophila receptor-linked protein tyrosine phosphatase.

1994 • 30 citations

The membrane protein A5, a putative neuronal recognition molecule, promotes neurite outgrowth

1993 • 23 citations

Drosophila protein tyrosine phosphatases

1993 • 21 citations

O-phospho-L-tyrosine inhibits cellular growth by activating protein tyrosine phosphatases.

1993 • 15 citations

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