The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

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Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

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Tamoxifen in the Treatment of Breast Cancer

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Menopausal Hormone Replacement Therapy and Risk of Ovarian Cancer

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The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells.

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A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

1991 • 538 citations

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The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods.

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The molecular role of Myc in growth and transformation: recent discoveries lead to new insights

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Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization

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Estrogen Receptor Expression in Benign Breast Epithelium and Breast Cancer Risk

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CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans.

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2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a Carcinogen in High- Temperature-Cooked Meat, and Breast Cancer Risk

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Quantification of the carcinogens 2-amino-3,8-dimethyl- and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in food using a combined assay based on gas chromatography—negative ion mass spectrometry

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Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phnylimidazo(4,5-b)pyridine (PhIP) by human liver microsomes

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Bioactivation of the cooked food mutagen N-hydroxy-2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine by estrogen sulfotransferase in cultured human mammary epithelial cells

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Synthetic progestins induce proliferation of breast tumor cell lines via the progesterone or estrogen receptor

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Detection of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) in the Milk of Healthy Women

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Mutagenic activity and heterocyclic amine content of the human diet.

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New insights in oestrogen receptor (ER) research — the ERβ

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Menopausal Hormone Replacement

1985 • 1 citations