Nitric Oxide–Mediated Induction of Ferritin Synthesis in J774 Macrophages by Inflammatory Cytokines: Role of Selective Iron Regulatory Protein-2 Downregulation

The ferritins: molecular properties, iron storage function and cellular regulation

1996 • 2,572 citations

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

1996 • 1,311 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

1988 • 684 citations

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA

1989 • 511 citations

Iron regulates nitric oxide synthase activity by controlling nuclear transcription.

1994 • 413 citations

Biosynthesis of nitric oxide activates iron regulatory factor in macrophages.

1993 • 409 citations

Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway.

1993 • 393 citations

Induction of Ferritin Synthesis by Oxidative Stress

1995 • 321 citations

Aconitase, a two‐faced protein: enzyme and iron regulatory factor ^{1 2}

1993 • 269 citations

Iron-sulfur clusters as biosensors of oxidants and iron.

1996 • 239 citations

Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts.

1995 • 226 citations

Linkage of cell-mediated immunity to iron metabolism

1995 • 209 citations

Iron-sulfur clusters as biosensors of oxidants and iron

1996 • 201 citations

Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13.

1997 • 181 citations

Recombinant iron‐regulatory factor functions as an iron‐responsive‐element‐binding protein, a translational repressor and an aconitase

1993 • 144 citations

Iron-Dependent Regulation of Ferritin and Transferrin Receptor Expression by the Iron-Responsive Element Binding Protein

1992 • 132 citations

Superoxide and hydrogen peroxide‐dependent inhibition of iron regulatory protein activity: a protective stratagem against oxidative injury

1996 • 127 citations

Iron Regulatory Proteins 1 and 2 Bind Distinct Sets of RNA Target Sequences

1996 • 115 citations

Conservation of ferritin heavy subunit gene structure: implications for the regulation of ferritin gene expression.

1987 • 109 citations

Inappropriately High Iron Regulatory Protein Activity in Monocytes of Patients With Genetic Hemochromatosis

1997 • 100 citations

Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse

1989 • 99 citations

Conservation in rat liver of light and heavy subunit sequences of mammalian ferritin. Presence of unique octopeptide in the light subunit.

1984 • 89 citations

Gamma-interferon modulates human monocyte/macrophage transferrin receptor expression

1988 • 80 citations

Requirements for the Translational Repression of Ferritin Transcripts in Wheat Germ Extracts by a 90-kDa Protein from Rabbit Liver

1989 • 80 citations

Transferrin receptor gene expression during rat liver regeneration. Evidence for post-transcriptional regulation by iron regulatory factorB, a second iron-responsive element-binding protein.

1994 • 76 citations

Differential regulation of IRP1 and IRP2 by nitric oxide in rat hepatoma cells

1996 • 72 citations

Modulation by nitric oxide of metalloprotein regulatory activities

1996 • 70 citations

cDNA cloning of the murine transferrin receptor: sequence of trans-membrane and adjacent regions.

1985 • 68 citations

The Heme Moiety of Malaria Pigment (β-Hematin) Mediates the Inhibition of Nitric Oxide and Tumor Necrosis Factor-α Production by Lipopolysaccharide-Stimulated Macrophages

1995 • 64 citations

Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line

1997 • 62 citations

Iron regulatory proteins 1 and 2

1996 • 56 citations

Nitric‐Oxide‐Mediated Activation of Iron‐Regulatory Protein Controls Hepatic Iron Metabolism During Acute Inflammation

1995 • 53 citations

Nitric oxide and the post-transcriptional control of cellular iron traffic

1994 • 46 citations

The Role of Nitric Oxide in the Regulation of Cellular Iron Metabolism

1997 • 40 citations

Effects of Nitrogen Monoxide on Cellular Iron Metabolism

1996 • 25 citations