Recombinant iron‐regulatory factor functions as an iron‐responsive‐element‐binding protein, a translational repressor and an aconitase

Molecular cloning: A laboratory manual

1990 • 85,659 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

1987 • 2,098 citations

The biological chemistry of the elements: the inorganic chemistry of life

1992 • 1,298 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

1988 • 684 citations

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA

1989 • 511 citations

Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus.

1991 • 464 citations

Sequence-Specific Binding of Transfer RNA by Glyceraldehyde-3-Phosphate Dehydrogenase

1993 • 461 citations

Oxidation-Reduction and the Molecular Mechanism of a Regulatory RNA-Protein Interaction

1989 • 387 citations

Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNA.

1991 • 374 citations

Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA

1988 • 363 citations

Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA.

1991 • 349 citations

Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein.

1992 • 345 citations

Regulation of ferritin and transferrin receptor mRNAs.

1990 • 339 citations

Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

1992 • 324 citations

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

1989 • 314 citations

Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B" and their cognate RNAs

1990 • 283 citations

Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.

1992 • 272 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

1989 • 244 citations

Translational control of 5-aminolevulinate synthase mRNA by iron-responsive elements in erythroid cells.

1993 • 210 citations

A regulated RNA binding protein also possesses aconitase activity.

1991 • 204 citations

Mechanism of Aconitase Action

1967 • 197 citations

Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase

1991 • 183 citations

Identification of an RNA binding site for human thymidylate synthase.

1993 • 178 citations

Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo.

1990 • 147 citations

The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein.

1989 • 144 citations

Position Is the Critical Determinant for Function of Iron-Responsive Elements as Translational Regulators

1992 • 138 citations

Purification of a Specific Repressor of Ferritin mRNA Translation from Rabbit Liver

1989 • 138 citations

Translational regulation by mRNA/protein interactions in eukaryotic cells: Ferritin and beyond

1993 • 134 citations

Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function?

1992 • 133 citations

Coordmation of cellular iron metabolism by post-transcriptional gene regulation

1992 • 121 citations

A model for the structure and functions of iron-responsive elements

1988 • 119 citations

Derepression of Ferritin Mmessenger RNA Translation by Hemin in Vitro

1990 • 118 citations

Ferritin mRNA: interactions of iron regulatory element with translational regulator protein P-90 and the effect on base-paired flanking regions.

1991 • 95 citations

High expression of functional adenovirus DNA polymerase and precursor terminal protein using recombinant vaccinia virus

1988 • 94 citations

Iron regulatory factor expressed from recombinant baculovirus: conversion between the RNA-binding apoprotein and Fe-S cluster containing aconitase

1993 • 93 citations

A high yield affinity purification method for specific RNA-binding proteins: isolation of the iron regulatory factor from human placenta

1990 • 85 citations

Requirements for the Translational Repression of Ferritin Transcripts in Wheat Germ Extracts by a 90-kDa Protein from Rabbit Liver

1989 • 80 citations

The iron-responsive element binding protein. Purification, cloning, and regulation in rat liver.

1992 • 78 citations

Position is the critical determinant for function of iron-responsive elements as translational regulators.

1992 • 77 citations

Binding of cytosolic aconitase to the iron responsive element of porcine mitochondrial aconitase mRNA

1992 • 74 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

1989 • 72 citations

Expression of active iron regulatory factor from a full length human cDNA byin vitrotranscription/translation

1992 • 69 citations

Cloning of a functional cDNA for the rabbit ferritin mRNA repressor protein. Demonstration of a tissue-specific pattern of expression.

1992 • 56 citations

Enhanced Degradation of the Ferritin Repressor Protein During Induction of Ferritin Messenger RNA Translation

1992 • 52 citations

Iron release from haemosiderin and ferritin by therapeutic and physiological chelators

1989 • 41 citations

Sequence and expression of the murine iron-responsive element binding protein

1991 • 39 citations

Effect of heparin contained in preparations of small cytoplasmic RNAs on cell-free translation

1991 • 10 citations