Iron-sulfur clusters as biosensors of oxidants and iron

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

The inactivation of Fe-S cluster containing hydro-lyases by superoxide.

1993 • 628 citations

Density-Functional Theory of Spin Polarization and Spin Coupling in Iron—Sulfur Clusters

1992 • 597 citations

Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis.

1993 • 579 citations

Superoxide sensitivity of the Escherichia coli aconitase.

1991 • 499 citations

Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway.

1993 • 393 citations

The role of iron in the activation-inactivation of aconitase.

1983 • 379 citations

Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein.

1992 • 345 citations

Rapid responses to oxidative stress mediated by iron regulatory protein.

1995 • 331 citations

Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

1992 • 324 citations

Superoxide sensitivity of the Escherichia coli 6-phosphogluconate dehydratase

1991 • 259 citations

Structure of the Allosteric Regulatory Enzyme of Purine Biosynthesis

1994 • 235 citations

Crystal structures of aconitase with isocitrate and nitroisocitrate bound

1992 • 214 citations

Aerobic-anaerobic gene regulation in Escherichia coli: control by the ArcAB and Fnr regulons

1994 • 209 citations

Binuclear [2Fe-2S] Clusters in the Escherichia coli SoxR Protein and Role of the Metal Centers in Transcription

1995 • 206 citations

Association of a polynuclear iron-sulfur center with a mutant FNR protein enhances DNA binding.

1995 • 186 citations

Mutational analysis of the [4Fe-4S]-cluster converting iron regulatory factor from its RNA-binding form to cytoplasmic aconitase.

1994 • 176 citations

ATP-dependent Regulation of Sodium-Calcium Exchange in Chinese Hamster Ovary Cells Transfected with the Bovine Cardiac Sodium-Calcium Exchanger

1995 • 160 citations

Oxidative Stress Induces Activation of a Cytosolic Protein Responsible for Control of Iron Uptake

1995 • 146 citations

Recombinant iron‐regulatory factor functions as an iron‐responsive‐element‐binding protein, a translational repressor and an aconitase

1993 • 144 citations

The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation.

1994 • 134 citations

The Oxygen Sensitivity of Spinach Ferredoxin and Other Iron-Sulfur Proteins

1971 • 132 citations

Iron-sulfur proteins: spin-coupling model for three-iron clusters.

1980 • 124 citations

The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft.

1994 • 122 citations

The state of cluster SH and S2- of aconitase during cluster interconversions and removal. A convenient preparation of apoenzyme.

1988 • 103 citations

Overproduction and Physical Characterization of SoxR, a [2Fe-2S] Protein That Governs an Oxidative Response Regulon in Escherichia coli

1995 • 102 citations

Differential Modulation of the RNA-binding Proteins IRP-1 and IRP-2 in Response to Iron

1995 • 98 citations

Iron regulatory factor expressed from recombinant baculovirus: conversion between the RNA-binding apoprotein and Fe-S cluster containing aconitase

1993 • 93 citations

No soup for starters? Autotrophy and the origins of metabolism

1995 • 81 citations

[3Fe-4S] to [4Fe-4S] cluster conversion in Escherichia coli fumarate reductase by site-directed mutagenesis

1992 • 79 citations

Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation.

1992 • 75 citations

Iron regulatory factor — the conductor of cellular iron regulation

1993 • 70 citations

Subsite-differentiated analogs of native iron sulfide [4Fe-4S]2+ clusters: preparation of clusters with five- and six-coordinate subsites and modulation of redox potentials and charge distributions

1990 • 70 citations

Complexes and Complexities of the Citric Acid Cycle in Escherichia coli

1992 • 59 citations

Characterization of FNR* mutant proteins indicates two distinct mechanisms for altering oxygen regulation of the Escherichia coli transcription factor FNR

1995 • 46 citations

Role of aromatic residues in stabilization of the [Fe4S4] cluster in high-potential iron proteins (HiPIPs): physical characterization and stability studies of Tyr-19 mutants of Chromatium vinosum HiPIP.

1995 • 41 citations

Localization of an RNA binding element of the iron responsive element binding protein within a proteolytic fragment containing iron coordination ligands

1994 • 33 citations

The active site sulfhydryl of aconitase is not required for catalytic activity.

1988 • 30 citations

A novel method to identify nucleic acid binding sites in protiens by scanning mutagenesis: application to iron regulatory protein

1995 • 20 citations