Synapse-specific and neuregulin-induced transcription require an Ets site that binds GABPα/GABPβ

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1993 • 1,313 citations

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1995 • 1,272 citations

Multiple essential functions of neuregulin in development

1995 • 1,236 citations

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

1995 • 1,108 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

The Ets family of transcription factors

1993 • 848 citations

Synaptic structure and development: The neuromuscular junction

1993 • 846 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Utrophin-Dystrophin-Deficient Mice as a Model for Duchenne Muscular Dystrophy

1997 • 710 citations

The Agrin Hypothesis

1990 • 637 citations

Skeletal and Cardiac Myopathies in Mice Lacking Utrophin and Dystrophin: A Model for Duchenne Muscular Dystrophy

1997 • 625 citations

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

1993 • 612 citations

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

1992 • 579 citations

Isolation of the NeuHER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells

1992 • 534 citations

Convergence of Ets- and Notch-Related Structural Motifs in a Heteromeric DNA Binding Complex

1991 • 464 citations

Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury

1995 • 409 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

Concentration of acetylcholine receptor mRNA in synaptic regions of adult muscle fibres

1985 • 344 citations

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

1994 • 315 citations

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1988 • 289 citations

The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA

1998 • 287 citations

Neu and its ligands: From an oncogene to neural factors

1993 • 286 citations

ARIA: A Neuromuscular Junction Neuregulin

1997 • 279 citations

Neuregulins are concentrated at nerve-muscle synapses and activate ACh–receptor gene expression

1995 • 276 citations

Maintenance of Acetylcholine Receptor Number by Neuregulins at the Neuromuscular Junction in Vivo

1997 • 272 citations

Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins.

1992 • 267 citations

Acetylcholine receptor gene expression at the developing neuromuscular junction.

1995 • 215 citations

A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway.

1994 • 198 citations

The formation of neuromuscular synapses

1998 • 189 citations

Selective expression of an acetylcholine receptor–lacZ transgene in synaptic nuclei of adult muscle fibers

1991 • 178 citations

Neuregulins and their receptors

1995 • 178 citations

Evolutionarily conserved Ets family members display distinct DNA binding specificities.

1992 • 175 citations

Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses.

1995 • 172 citations

Synapse-Associated Expression of an Acetylcholine Receptor-Inducing Protein, ARIA/Heregulin, and Its Putative Receptors, ErbB2 and ErbB3, in Developing Mammalian Muscle

1995 • 170 citations

Implication of a multisubunit Ets-related transcription factor in synaptic expression of the nicotinic acetylcholine receptor

1998 • 153 citations

Localization of nicotinic acetylcholine receptor alpha-subunit transcripts during myogenesis and motor endplate development in the chick.

1989 • 146 citations

ARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway.

1996 • 131 citations

ErbB3 and ErbB2/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate.

1995 • 131 citations

Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity

1997 • 130 citations

Spatial and temporal expression of acetylcholine receptor RNAs in innervated and denervated rat soleus muscle

1989 • 129 citations

Regulation of the acetylcholine receptor ϵ subunit gene by recombinant ARIA: An in vitro model for transynaptic gene regulation

1995 • 127 citations

Spatial restriction of AChR gene expression to subsynaptic nuclei

1992 • 122 citations

Four Structurally Distinct, Non-DNA-Binding Subunits of Human Nuclear Respiratory Factor 2 Share a Conserved Transcriptional Activation Domain

1995 • 122 citations

ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development.

1994 • 121 citations

A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells

1992 • 113 citations

FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements

1997 • 107 citations

Compartmentalization of acetylcholinesterase mRNA and enzyme at the vertebrate neuromuscular junction

1993 • 106 citations

Purification of a set of cellular polypeptides that bind to the purine-rich cis-regulatory element of herpes simplex virus immediate early genes.

1989 • 105 citations

Induction of Acetylcholine Receptor Gene Expression by ARIA Requires Activation of Mitogen-activated Protein Kinase

1996 • 103 citations

NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells.

1995 • 101 citations

Identification of a DNA element determining synaptic expression of the mouse acetylcholine receptor delta-subunit gene.

1995 • 101 citations

Identification of an Element Crucial for the Sub-synaptic Expression of the Acetylcholine Receptor ε-Subunit Gene

1996 • 96 citations

Expression of the PEA3 group of ETS-related transcription factors in human breast-cancer cells

1997 • 91 citations

Muscle and Neural Isoforms of Agrin Increase Utrophin Expression in Cultured Myotubes via a Transcriptional Regulatory Mechanism

1998 • 90 citations

Molecular and genetic characterization of GABP beta.

1994 • 89 citations

An E box mediates activation and repression of the acetylcholine receptor delta-subunit gene during myogenesis.

1993 • 89 citations

Raf-1 kinase targets GA-binding protein in transcriptional regulation of the human immunodeficiency virus type 1 promoter

1996 • 89 citations

An acetylcholine receptor alpha-subunit promoter conferring preferential synaptic expression in muscle of transgenic mice.

1991 • 88 citations

Characterization of NERF, a Novel Transcription Factor Related to the Ets Factor ELF-1

1996 • 86 citations

ARIA is concentrated in the synaptic basal lamina of the developing chick neuromuscular junction.

1995 • 86 citations

N-CAM, 43K-Rapsyn, and S-Laminin mRNAs Are Concentrated at Synaptic Sites in Muscle Fibers

1995 • 81 citations

Neural regulation of muscle acetylcholine receptor epsilon- and alpha-subunit gene promoters in transgenic mice.

1993 • 80 citations

In vivo and in vitro analysis of electricalactivity-dependent expression of muscle acetylcholine receptor genes usingadenovirus.

1994 • 78 citations

Molecular characterization of the ets-related human transcription factor ER81.

1995 • 77 citations

Local Transcriptional Control of Utrophin Expression at the Neuromuscular Synapse

1997 • 77 citations

The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase

1998 • 73 citations

Separate pathways for synapse-specific and electrical activity-dependent gene expression in skeletal muscle

1994 • 72 citations

GABP Mediates Insulin-increased Prolactin Gene Transcription

1996 • 68 citations

Neuregulins and erbB Receptors at Neuromuscular Junctions and at Agrin-Induced Postsynaptic-like Apparatus in Skeletal Muscle

1998 • 67 citations

Identification of a neuregulin and protein-tyrosine phosphatase response element in the nicotinic acetylcholine receptor ɛ subunit gene: Regulatory role of an Ets transcription factor

1998 • 60 citations

An 83-nucleotide promoter of the acetylcholine receptor epsilon-subunit gene confers preferential synaptic expression in mouse muscle.

1993 • 56 citations

Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha.

1996 • 52 citations

ERP, a New Member of the ets Transcription Factor/Oncoprotein Family: Cloning, Characterization, and Differential Expression during B-Lymphocyte Development

1994 • 37 citations

Identification of an Element Required for Acetylcholine Receptor-inducing Activity (ARIA)-induced Expression of the Acetylcholine Receptor ε Subunit Gene

1997 • 25 citations

ELF-1 Interacts with and Transactivates the IgH Enhancer π Site

1996 • 21 citations

Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia

1997 • 15 citations

An E Box Mediates Activation and Repression of the Acetylcholine Receptor δ-Subunit Gene during Myogenesis

1993 • 15 citations

Synapse-specific gene expression

1995 • 7 citations