Utrophin-Dystrophin-Deficient Mice as a Model for Duchenne Muscular Dystrophy

X chromosome-linked muscular dystrophy (mdx) in the mouse.

1984 • 1,678 citations

The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation

1989 • 1,171 citations

Duchenne Muscular Dystrophy

1995 • 1,084 citations

Three myosin heavy chain isoforms in type 2 skeletal muscle fibres

1989 • 965 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkage

1995 • 829 citations

MyoD is required for myogenic stem cell function in adult skeletal muscle.

1996 • 705 citations

Skeletal and Cardiac Myopathies in Mice Lacking Utrophin and Dystrophin: A Model for Duchenne Muscular Dystrophy

1997 • 625 citations

Myosin isoforms in mammalian skeletal muscle

1994 • 517 citations

Muscle Disorders in Childhood

2015 • 491 citations

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle

1992 • 489 citations

Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene

1996 • 475 citations

Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury

1995 • 409 citations

THE MUTANT mdx: INHERITED MYOPATHY IN THE MOUSE

1987 • 352 citations

Development, Innervation, and Activity-Pattern Induced Changes in Skeletal Muscle

1981 • 328 citations

Distribution of Na+ channels and ankyrin in neuromuscular junctions is complementary to that of acetylcholine receptors and the 43 kd protein

1989 • 274 citations

Duchenne muscular dystrophy

1993 • 260 citations

Dystrophin-associated proteins in muscular dystrophy

1995 • 242 citations

Subtle Neuromuscular Defects in Utrophin-deficient Mice

1997 • 216 citations

Postsynaptic Abnormalities at the Neuromuscular Junctions of Utrophin-deficient Mice

1997 • 215 citations

Utrophin actin binding domain: analysis of actin binding and cellular targeting

1995 • 215 citations

Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex

1995 • 209 citations

Increasing complexity of the dystrophin-associated protein complex.

1994 • 194 citations

Structure and function of the neuromuscular junction in young adultmdx mice

1991 • 179 citations

New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin

1993 • 178 citations

The dystrophin-related protein, utrophin, is expressed on the sarcolemma of regenerating human skeletal muscle fibres in dystrophies and inflammatory myopathies

1992 • 168 citations

Utrophin: A Structural and Functional Comparison to Dystrophin

1996 • 168 citations

Dystrophin-related protein, utrophin, in normal and dystrophic human fetal skeletal muscle

1993 • 144 citations

Localization of dystrophin relative to acetylcholine receptor domains in electric tissue and adult and cultured skeletal muscle.

1991 • 140 citations

Localization and Quantitation of the Chromosome 6-Encoded Dystrophin-Related Protein in Normal and Pathological Human Muscle

1993 • 139 citations

Different distributions of dystrophin and related proteins at nerve-muscle junctions

1992 • 131 citations

β2-Syntrophin

1994 • 127 citations

Ultrastructure of the skeletal muscle in the X chromosome-linked dystrophic (mdx) mouse

1988 • 112 citations

Evidence for myoblast-extrinsic regulation of slow myosin heavy chain expression during muscle fiber formation in embryonic development.

1993 • 112 citations

The mdx-amplification-resistant mutation system assay, a simple and rapid polymerase chain reaction-based detection of the mdx allele

1996 • 90 citations

Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis

1994 • 90 citations

Morphology of diaphragm neuromuscular junctions on different fibre types

1996 • 73 citations

Neural regulation of enzymes in muscle fibers of red and white muscle

1967 • 72 citations

Neuromuscular transmission in the mdx mouse

1990 • 68 citations

Utrophin localization in normal and dystrophin-deficient heart.

1994 • 64 citations

Genes at the junction—candidates for congenital myasthenic syndromes

1997 • 62 citations

Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?

1994 • 52 citations

DUCHENNE DYSTROPHY

1974 • 51 citations

Expression of myosin heavy chain isoforms in Duchenne muscular dystrophy patients and carriers

1991 • 46 citations

Site and mechanics of failure in normal and dystrophin‐deficient skeletal muscle

1995 • 43 citations

Expression of dystrophin-associated glycoproteins and utrophin in carriers of Duchenne muscular dystrophy

1994 • 29 citations

Muscle Disorders in Childhood

1979 • 15 citations