Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

2012 • 10,051 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Running enhances neurogenesis, learning, and long-term potentiation in mice

1999 • 2,829 citations

AMPA Receptor Trafficking and Synaptic Plasticity

2002 • 2,540 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Neurogenesis in the adult is involved in the formation of trace memories

2001 • 2,014 citations

Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function

2005 • 1,906 citations

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.

2000 • 1,878 citations

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

2000 • 1,311 citations

Increased hippocampal neurogenesis in Alzheimer's disease

2003 • 955 citations

Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17

1998 • 954 citations

Doublecortin expression levels in adult brain reflect neurogenesis

2005 • 942 citations

Neurogenesis may relate to some but not all types of hippocampal‐dependent learning

2002 • 854 citations

The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis

2002 • 752 citations

Kinesin Superfamily Motor Protein KIF17 and mLin-10 in NMDA Receptor-Containing Vesicle Transport

2000 • 700 citations

The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro

1992 • 545 citations

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

2002 • 517 citations

Disruption of Dendritic Translation of CaMKIIα Impairs Stabilization of Synaptic Plasticity and Memory Consolidation

2002 • 507 citations

Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice

2001 • 495 citations

Cell-Cycle Reentry and Cell Death in Transgenic Mice Expressing Nonmutant Human Tau Isoforms

2005 • 485 citations

On the delay-dependent involvement of the hippocampus in object recognition memory

2004 • 451 citations

Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

2004 • 395 citations

Mutations causing neurodegenerative tauopathies

2004 • 392 citations

Defects in Axonal Elongation and Neuronal Migration in Mice with Disrupted tau and map1b Genes

2000 • 388 citations

Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein

1999 • 378 citations

The Ki-67 Protein: Fascinating Forms and an Unknown Function

2000 • 372 citations

Perspectives on object-recognition memory following hippocampal damage: lessons from studies in rats

2001 • 348 citations

Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible

2003 • 315 citations

Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice

2000 • 313 citations

Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus–pituitary–adrenal axis activation

2003 • 311 citations

Functionally Dissociating Aspects of Event Memory: the Effects of Combined Perirhinal and Postrhinal Cortex Lesions on Object and Place Memory in the Rat

1999 • 253 citations

Changed Conformation of Mutant Tau-P301L Underlies the Moribund Tauopathy, Absent in Progressive, Nonlethal Axonopathy of Tau-4R/2N Transgenic Mice

2004 • 252 citations

Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau

2002 • 251 citations

Chronic unpredictable stress impairs long‐term potentiation in rat hippocampal CA1 area and dentate gyrus in vitro

2003 • 251 citations

Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP

2004 • 245 citations

Neuronal Deficiency of Presenilin 1 Inhibits Amyloid Plaque Formation and Corrects Hippocampal Long-Term Potentiation But Not a Cognitive Defect of Amyloid Precursor Protein [V717I] Transgenic Mice

2002 • 235 citations

Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau

2002 • 229 citations

Phenotypic variation in hereditary frontotemporal dementia with tau mutations

1999 • 222 citations

REVIEW: tau protein pathology in Alzheimer’s disease and related disorders

1999 • 206 citations

Retarded Axonal Transport of R406W Mutant Tau in Transgenic Mice with a Neurodegenerative Tauopathy

2004 • 186 citations

Genetic dissection of mouse exploratory behaviour

2001 • 185 citations

Tau gene mutations: dissecting the pathogenesis of FTDP-17

2002 • 174 citations

Memory traces of trace memories: neurogenesis, synaptogenesis and awareness

2004 • 164 citations

Defining Molecular Targets to Prevent Alzheimer Disease

2005 • 155 citations

Isoforms changes of tau protein during development in various species

2003 • 148 citations

Distinct Contributions of Hippocampal NMDA and AMPA Receptors to Encoding and Retrieval of One-Trial Place Memory

2005 • 145 citations

Transgenic animal models of tauopathies

2004 • 135 citations

Influence of Separate and Combined Septal and Amygdala Lesions on Memory, Acoustic Startle, Anxiety, and Locomotor Activity in Rats

1995 • 127 citations

Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's Disease: linkage of poorer cognitive performance to tau pathology in forebrain

2004 • 121 citations

Cdk5, a therapeutic target for Alzheimer's disease?

2003 • 120 citations

Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic Mice

2005 • 119 citations

Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice

2004 • 91 citations

Hereditary Pick's disease with the G272V tau mutation shows predominant three-repeat tau pathology

2005 • 86 citations

Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression

2003 • 84 citations

A behavioural characterisation of the FVB/N mouse strain

2004 • 69 citations

The FTDP‐17‐Linked Mutation R406W Abolishes the Interaction of Phosphorylated Tau with Microtubules

2000 • 67 citations

NMDA Receptor Antagonists

1998 • 65 citations

Microtubule Regulation of N-Methyl-D-aspartate Receptor Channels in Neurons

2005 • 54 citations

Bilateral injection of isoproterenol into hippocampus induces Alzheimer‐like hyperphosphorylation of tau and spatial memory deficit in rat

2004 • 43 citations

Depolarization stimulates lamellipodia formation and axonal but not dendritic branching in cultured rat cerebral cortex neurons

1998 • 39 citations

A Neural Circuit Analysis of Visual Recognition Memory: Role of Perirhinal, Medial, and Lateral Entorhinal Cortex

2001 • 37 citations

PKA Phosphorylations on Tau: Developmental Studies in the Mouse

2000 • 33 citations

A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis

2003 • 31 citations

Open Field Motor Patterns and Object Marking, but Not Object Sniffing, Are Altered by Ibotenate Lesions of the Hippocampus

1999 • 25 citations

Specific tau phosphorylation sites in hippocampus correlate with impairment of step-down inhibitory avoidance task in rats

2004 • 23 citations

Suppression of Cell Division by pKi-67 Antisense-RNA and Recombinant Protein

2001 • 20 citations