Specific tau phosphorylation sites in hippocampus correlate with impairment of step-down inhibitory avoidance task in rats

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Neuropathological stageing of Alzheimer-related changes

1991 • 14,533 citations

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1992 • 2,520 citations

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

1988 • 1,073 citations

Tau in Alzheimer's disease

1998 • 936 citations

Tau protein and the neurofibrillary pathology of Alzheimer's disease

1993 • 710 citations

Time-dependent reorganization of brain circuitry underlying long-term memory storage

1999 • 650 citations

Phosphoprotein Phosphatase Activities in Alzheimer Disease Brain

1993 • 504 citations

Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats

1997 • 500 citations

Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: Sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau

1997 • 408 citations

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

1994 • 349 citations

Phosphorylation of Tau at Both Thr 231 and Ser 262 Is Required for Maximal Inhibition of Its Binding to Microtubules

1998 • 321 citations

CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects

2002 • 248 citations

Brain regions associated with episodic retrieval in normal aging and Alzheimer’s disease

1999 • 212 citations

Role of dorsal hippocampus in acquisition, consolidation and retrieval of rat's passive avoidance response: a tetrodotoxin functional inactivation study

1996 • 205 citations

Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved Mouse

2001 • 193 citations

An analysis of memory dysfunction in major depression

1995 • 193 citations

Involvement of hippocampal D1/D5 receptor-cAMP signaling pathways in a late memory consolidation phase of an aversively-motivated task in rats

1997 • 188 citations

Patterns of hippocampal-cortical interaction dissociate temporal lobe memory subsystems

2000 • 187 citations

Role of protein phosphatase‐2A and ‐1 in the regulation of GSK‐3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain

2000 • 185 citations

The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease

1992 • 167 citations

Assembly of Alzheimer‐like filaments from full‐length tau protein

1994 • 154 citations

Protein Phosphatase 1 Is Targeted to Microtubules by the Microtubule-associated Protein Tau

1998 • 144 citations

Selective Destruction of Stable Microtubules and Axons by Inhibitors of Protein Serine/Threonine Phosphatases in Cultured Human Neurons (NT2N Cells)

1997 • 142 citations

The Repeat Region of Microtubule-Associated Protein Tau Forms Part of the Core of the Paired Helical Filament of Alzheimer's Disease

1989 • 88 citations

Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain

2000 • 80 citations

Post-training intrahippocampal infusion of protein kinase C inhibitors causes amnesia in rats

1994 • 71 citations

Protein Phosphatase-Mediated Regulation of Protein Kinase C during Long-Term Depression in the Adult HippocampusIn Vivo

2000 • 67 citations

Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment

1999 • 66 citations

Concentration-Dependent Effects of Protein Phosphatase (PP) Inhibitors Implicate PP1 and PP2A in Different Stages of Memory Formation

2001 • 26 citations

Tau protein and Alzheimer's disease

1994 • 24 citations

The pattern of deficit in different memory components in normal aging and dementia of alzheimer's type

1994 • 21 citations

A Kinase to Dampen the Effects of Cocaine?

2001 • 15 citations