A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

SMART, a simple modular architecture research tool: Identification of signaling domains

1998 • 3,523 citations

Genomic Libraries and a Host Strain Designed for Highly Efficient Two-Hybrid Selection in Yeast

1996 • 2,631 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1997 • 1,814 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

1994 • 985 citations

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1997 • 819 citations

A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins

1997 • 750 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 671 citations

Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis

1997 • 654 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1997 • 525 citations

Anillin, a contractile ring protein that cycles from the nucleus to the cell cortex.

1995 • 423 citations

cdc12p, a Protein Required for Cytokinesis in Fission Yeast, Is a Component of the Cell Division Ring and Interacts with Profilin

1997 • 415 citations

diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene

1994 • 408 citations

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1999 • 397 citations

The Rho GTPase and a Putative RhoGEF Mediate a Signaling Pathway for the Cell Shape Changes in Drosophila Gastrulation

1997 • 384 citations

Intracellular localization of the P21rho proteins.

1992 • 382 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

1993 • 363 citations

Sequence analysis and neuronal expression of fasciclin I in grasshopper and drosophila

1988 • 363 citations

The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins

1994 • 346 citations

A purified Drosophila septin complex forms filaments and exhibits GTPase activity.

1996 • 327 citations

UNC-73 Activates the Rac GTPase and Is Required for Cell and Growth Cone Migrations in C. elegans

1998 • 319 citations

Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis.

1995 • 317 citations

Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product.

1994 • 314 citations

DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila

1998 • 309 citations

The pleckstrin homology domain: An intriguing multifunctional protein module

1996 • 285 citations

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila

1991 • 281 citations

Oncogene ect2 is related to regulators of small GTP-binding proteins

1993 • 281 citations

Dbl family proteins

1997 • 260 citations

A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos

1997 • 259 citations

Cytokinesis in eukaryotes: a mechanistic comparison

1999 • 238 citations

A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs

1993 • 230 citations

Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein

1993 • 224 citations

Crystal Structure of the Dbl and Pleckstrin Homology Domains from the Human Son of Sevenless Protein

1998 • 220 citations

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

1991 • 211 citations

FH proteins as cytoskeletal organizers

1998 • 195 citations

Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows.

1995 • 192 citations

Expression Cloning of lfc, a Novel Oncogene with Structural Similarities to Guanine Nucleotide Exchange Factors and to the Regulatory Region of Protein Kinase C

1995 • 188 citations

Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis

1998 • 178 citations

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

1999 • 177 citations

Localization and possible functions of Drosophila septins.

1995 • 172 citations

NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio

1998 • 171 citations

Roles of Rho-associated Kinase in Cytokinesis; Mutations in Rho-associated Kinase Phosphorylation Sites Impair Cytokinetic Segregation of Glial Filaments

1998 • 164 citations

Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs

1996 • 141 citations

The Pleckstrin Homology Domain Mediates Transformation by Oncogenic Dbl through Specific Intracellular Targeting

1996 • 136 citations

A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr.

1991 • 129 citations

Participation of small GTPases in dorsal closure of the Drosophila embryo: distinct roles for Rho subfamily proteins in epithelial morphogenesis

1999 • 129 citations

The Small GTP-binding Protein Rho Regulates Cortical Activities in Cultured Cells during Division

1999 • 125 citations

Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins.

1987 • 118 citations

A DNA‐Topoisomerase‐11–Binding Protein with Eight Repeating Regions Similar to DNA‐repair Enzymes and to a Cell‐Cycle Regulator

1997 • 116 citations

Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.

1995 • 113 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)

1994 • 100 citations

Nuclear antigens follow different pathways into daughter nuclei during mitosis in early Drosophila embryos

1986 • 98 citations

Persistence of major nuclear envelope antigens in an envelope-like structure during mitosis in Drosophila melanogaster embryos

1989 • 96 citations

A Role for Dictyostelium RacE in Cortical Tension and Cleavage Furrow Progression

1998 • 94 citations

The pebble gene is required for cytokinesis in Drosophila

1992 • 94 citations

P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster: Mutations Affecting Embryonic PNS Development

1997 • 87 citations

Isolation of Mutations in the Drosophila Homologues of the Human Neurofibromatosis 2 and Yeast CDC42 Genes Using a Simple and Efficient Reverse-Genetic Method

1997 • 85 citations

Zygotic expression of the pebble locus is required for cytokinesis during the postblastoderm mitoses of Drosophila

1992 • 85 citations

Activation of the Lbc Rho Exchange Factor Proto-Oncogene by Truncation of an Extended C Terminus That Regulates Transformation and Targeting

1999 • 84 citations

The role of anillin in meiotic cytokinesis of Drosophila males

1999 • 83 citations

[9] Guanine nucleotide exchange catalyzed by dbl oncogene product

1995 • 76 citations

Cellularization inDrosophila melanogasterIs Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function

1998 • 73 citations

Dominant Inhibitory Mutations in the Mg²⁺-Binding Site of Ras^H Prevent Its Activation by GTP

1991 • 68 citations

The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras Asn-17.

1993 • 52 citations

Localization of Rho GTPase in sea urchin eggs

1998 • 43 citations

Affinity purification of antibodies using antigens immobilized on solid supports

1988 • 21 citations

The Saccharomyces cerevisiae SDC25 C-Domain Gene Product Overcomes the Dominant Inhibitory Activity of Ha-Ras Asn-17

1993 • 17 citations