Oncogene ect2 is related to regulators of small GTP-binding proteins

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

1992 • 760 citations

GENETIC CONTROL OF THE CELL DIVISION CYCLE IN YEAST: V. GENETIC ANALYSIS OF cdc MUTANTS

1973 • 728 citations

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.

1990 • 605 citations

Bcr encodes a GTPase-activating protein for p21rac

1991 • 474 citations

Expression cDNA Cloning of the KGF Receptor by Creation of a Transforming Autocrine Loop

1991 • 427 citations

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product

1991 • 424 citations

Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.

1989 • 406 citations

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1991 • 375 citations

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

1992 • 361 citations

Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line

1990 • 285 citations

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide.

1991 • 281 citations

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

1991 • 273 citations

Isolation of a new human oncogene from a diffuse B-cell lymphoma

1985 • 210 citations

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

1990 • 204 citations

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

1990 • 202 citations

A calcium-dependent antibody for identification and purification of recombinant proteins.

1989 • 181 citations

Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42.

1990 • 172 citations

The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization

1992 • 170 citations

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.

1991 • 145 citations

Nucleotide sequence of human rho cDNA clone 12

1987 • 143 citations

Growth-regulated expression of rhoG, a new member of the ras homolog gene family.

1992 • 114 citations

cDNA sequence for human bcr, the gene that translocates to the abl oncogene in chronic myeloid leukaemia.

1987 • 107 citations

Nucleotide sequence of the CLS4 (CDC24) gene of Saccharomyces cerevisiae

1987 • 86 citations

An efficient directional cloning system to construct cDNA libraries containing full-length inserts at high frequency

1989 • 66 citations

A DBL-homologous region of the yeast gene product is important for Ca2+-modulated bud assembly

1991 • 33 citations