Participation of small GTPases in dorsal closure of the Drosophila embryo: distinct roles for Rho subfamily proteins in epithelial morphogenesis

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Molecular cloning: A laboratory manual

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Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

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Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Rho GTPases and signaling networks

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The embryonic development of Drosophila melanogaster

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The Embryonic Development of Drosophila melanogaster

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Drosophila: a laboratory manual

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The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

1994 • 985 citations

The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton

1996 • 866 citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

1995 • 711 citations

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of drosophila

1995 • 681 citations

Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

1997 • 601 citations

Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes

1997 • 560 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines

1996 • 454 citations

Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.

1993 • 424 citations

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

1997 • 415 citations

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.

1996 • 407 citations

The Rho GTPase and a Putative RhoGEF Mediate a Signaling Pathway for the Cell Shape Changes in Drosophila Gastrulation

1997 • 384 citations

Rho effectors and reorganization of actin cytoskeleton

1997 • 379 citations

Drosophila: A laboratory manual

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A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

1989 • 348 citations

hemipterous encodes a novel drosophila MAP kinase kinase, required for epithelial cell sheet movement

1995 • 331 citations

Cdc42 Regulates Anchorage-Independent Growth and Is Necessary for Ras Transformation

1997 • 312 citations

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

1996 • 310 citations

The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes

1994 • 306 citations

Regulation of Phosphorylation Pathways by p21 GTPases

1996 • 300 citations

Rho family GTPases: the cytoskeleton and beyond

1996 • 262 citations

Cytoplasmic myosin from Drosophila melanogaster.

1986 • 256 citations

Localization of p21-Activated Kinase 1 (PAK1) to Pinocytic Vesicles and Cortical Actin Structures in Stimulated Cells

1997 • 230 citations

Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis.

1996 • 216 citations

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila.

1996 • 215 citations

A Drosophila Homolog of the Rac- and Cdc42-Activated Serine/Threonine Kinase PAK Is a Potential Focal Adhesion and Focal Complex Protein That Colocalizes with Dynamic Actin Structures

1996 • 204 citations

Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis.

1997 • 200 citations

Kinase-Deficient Pak1 Mutants Inhibit Ras Transformation of Rat-1 Fibroblasts

1997 • 199 citations

Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure.

1997 • 194 citations

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

1995 • 190 citations

A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila

1995 • 169 citations

Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement.

1997 • 166 citations

JNK signaling and morphogenesis in Drosophila

1998 • 163 citations

Drosophila Rac1 controls motor axon guidance

1998 • 144 citations

Two distinct roles for Ras in a developmentally regulated cell migration

1996 • 143 citations

Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways.

1997 • 142 citations

Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.

1995 • 113 citations

Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.

1993 • 110 citations

Integrins hold Drosophila together

1993 • 97 citations

Genetics of signal transduction in invertebrates

1994 • 96 citations

A role for Pak protein kinases in Schwann cell transformation

1998 • 91 citations

Cellularization inDrosophila melanogasterIs Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function

1998 • 73 citations

Drosophila morphogenesis: Movements behind the edge

1997 • 40 citations

P Element-Mediated Germ-Line Transformation of Drosophila

2003 • 39 citations

Regulation of cell differentiation by the Drosophila Jun kinase cascade

1997 • 33 citations