Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

Cell Migration: Integrating Signals from Front to Back

2003 • 4,755 citations

Cellular Motility Driven by Assembly and Disassembly of Actin Filaments

2003 • 4,038 citations

ROCKs: multifunctional kinases in cell behaviour

2003 • 1,866 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

Actin-Based Cell Motility and Cell Locomotion

1996 • 1,536 citations

FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

2004 • 1,330 citations

Biology of the p21-Activated Kinases

2003 • 1,073 citations

Red fluorescent protein

2001 • 1,048 citations

Cytoskeletal dynamics and nerve growth

1988 • 855 citations

Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility

2002 • 828 citations

Divergent Signals and Cytoskeletal Assemblies Regulate Self-Organizing Polarity in Neutrophils

2003 • 690 citations

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells

2003 • 658 citations

Spatiotemporal Feedback between Actomyosin and Focal-Adhesion Systems Optimizes Rapid Cell Migration

2006 • 595 citations

Nuclear Movement Regulated by Cdc42, MRCK, Myosin, and Actin Flow Establishes MTOC Polarization in Migrating Cells

2005 • 590 citations

Periodic Lamellipodial Contractions Correlate with Rearward Actin Waves

2004 • 570 citations

RhoA is required for monocyte tail retraction during transendothelial migration

2001 • 498 citations

Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity

1975 • 413 citations

Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize

2006 • 372 citations

Growth cone advance is inversely proportional to retrograde F-actin flow

1995 • 371 citations

Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion

2004 • 352 citations

Focal Adhesion Motility Revealed in Stationary Fibroblasts

1999 • 345 citations

Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase

1980 • 338 citations

Nonmuscle Myosin Heavy Chain IIA Mutations Define a Spectrum of Autosomal Dominant Macrothrombocytopenias: May-Hegglin Anomaly and Fechtner, Sebastian, Epstein, and Alport-Like Syndromes

2001 • 292 citations

Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics

2006 • 290 citations

Nonmuscle Myosin IIA-Dependent Force Inhibits Cell Spreading and Drives F-Actin Flow

2006 • 285 citations

Nonmuscle Myosin IIB Is Involved in the Guidance of Fibroblast Migration

2003 • 237 citations

The GIT-Associated Kinase PAK Targets to the Centrosome and Regulates Aurora-A

2005 • 229 citations

Slipping or Gripping? Fluorescent Speckle Microscopy in Fish Keratocytes Reveals Two Different Mechanisms for Generating a Retrograde Flow of Actin

2004 • 204 citations

Components of cell-matrix adhesions

2001 • 200 citations

Conditional Expression of a Truncated Fragment of Nonmuscle Myosin II-A Alters Cell Shape but Not Cytokinesis in HeLa Cells

2000 • 181 citations

Cytoplasmic dynamics of myosin IIA and IIB: spatial ‘sorting’ of isoforms in locomoting cells

1998 • 177 citations

Cytoskeletal reorganization underlying growth cone motility

1994 • 169 citations

Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities.

1996 • 167 citations

The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL)

2001 • 164 citations

Quantifying Lamella Dynamics of Cultured Cells by SACED, a New Computer-Assisted Motion Analysis

1999 • 132 citations

Disease-associated Mutations and Alternative Splicing Alter the Enzymatic and Motile Activity of Nonmuscle Myosins II-B and II-C

2005 • 131 citations

Vertebrate Nonmuscle Myosin II Isoforms Rescue Small Interfering RNA-induced Defects in COS-7 Cell Cytokinesis

2005 • 115 citations

A Point Mutation in the Motor Domain of Nonmuscle Myosin II-B Impairs Migration of Distinct Groups of Neurons

2004 • 102 citations

Targeting Membrane-localized Focal Adhesion Kinase to Focal Adhesions

2003 • 89 citations

Genetic analysis of myosin II assembly and organization in model organisms

2005 • 43 citations

Cooperative structural change of actin filaments interacting with activated myosin motor domain, detected with copolymers of pyrene-labeled actin and acto-S1 chimera protein

2005 • 24 citations