Targeting Membrane-localized Focal Adhesion Kinase to Focal Adhesions

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Taking Cell-Matrix Adhesions to the Third Dimension

2001 • 2,940 citations

Transmembrane crosstalk between the extracellular matrix and the cytoskeleton

2001 • 2,141 citations

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1994 • 1,590 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN

1998 • 1,215 citations

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

1995 • 1,202 citations

Signaling through focal adhesion kinase

1999 • 1,169 citations

Control of adhesion-dependent cell survival by focal adhesion kinase.

1996 • 1,113 citations

Molecular complexity and dynamics of cell-matrix adhesions

2001 • 1,091 citations

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

1992 • 811 citations

Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate

1997 • 811 citations

Biochemical signals and biological responses elicited by the focal adhesion kinase

2001 • 568 citations

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

1999 • 542 citations

Integrins and Actin Filaments: Reciprocal Regulation of Cell Adhesion and Signaling

2000 • 476 citations

Evidence for In Vivo Phosphorylation of the Grb2 SH2-Domain Binding Site on Focal Adhesion Kinase by Src-Family Protein-Tyrosine Kinases

1996 • 450 citations

Molecular diversity of cell-matrix adhesions

1999 • 444 citations

Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten

1999 • 418 citations

Interaction of Focal Adhesion Kinase with Cytoskeletal Protein Talin

1995 • 393 citations

F-actin binding site masked by the intramolecular association of vinculin head and tail domains

1995 • 371 citations

Matrix Survival Signaling

2000 • 360 citations

Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression

2001 • 334 citations

Regulation of fibronectin receptor distribution [published erratum appears in J Cell Biol 1992 Jul;118(2):491]

1992 • 295 citations

Anchorage-dependent ERK signaling – mechanisms and consequences

2002 • 287 citations

Assembly of focal adhesions: progress, paradigms, and portents

1996 • 265 citations

Fibronectin and Integrins in Cell Adhesion, Signaling, and Morphogenesis

1998 • 235 citations

The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

2002 • 212 citations

Focal adhesion kinase promotes phospholipase C-γ1 activity

1999 • 181 citations

Mechanisms of CAS Substrate Domain Tyrosine Phosphorylation by FAK and Src

2001 • 158 citations

A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK.

1994 • 134 citations

Integrin Signaling: Tyrosine Phosphorylation Events in Focal Adhesions

1998 • 133 citations

PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates

2001 • 120 citations

pp60c-src and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions

2001 • 117 citations

Focal Adhesion Targeting: The Critical Determinant of FAK Regulation and Substrate Phosphorylation

1999 • 116 citations

Plasma Membrane-Associated pY397FAK Is a Marker of Cytotrophoblast Invasion in Vivo and in Vitro

2001 • 94 citations

Actin Activates a Cryptic Dimerization Potential of the Vinculin Tail Domain

2000 • 81 citations

Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies

2001 • 79 citations