Correlation between Pretreatment Levels of Interferon Response Genes and Clinical Responses to an Immune Response Modifier (Imiquimod) in Genital Warts

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

STATs and Gene Regulation

1997 • 3,927 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

1989 • 970 citations

Inhibition of Stat1-mediated gene activation by PIAS1

1998 • 760 citations

Self-administered Topical 5% Imiquimod Cream for External Anogenital Warts

1998 • 558 citations

The growing family of interferon regulatory factors

1997 • 480 citations

Review Article Imiquimod applied topically: a novel immune response modifier and new class of drug

1999 • 412 citations

STAT3 Is Required for the gp130-mediated Full Activation of the c-myc Gene

1999 • 383 citations

Treatment of genital warts with an immune-response modifier (imiquimod)

1998 • 308 citations

Regulation of STAT‐dependent pathways by growth factors and cytokines

1996 • 297 citations

Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system.

1994 • 288 citations

Negative regulation of the JAK/STAT pathway

1999 • 288 citations

Evidence for an Epidermal Cytokine Network

1990 • 278 citations

Cytokine induction by the immunomodulators imiquimod and S-27609

1995 • 268 citations

A Randomized, Controlled, Molecular Study of Condylomata Acuminata Clearance during Treatment with Imiquimod

1998 • 255 citations

The state of the STATs: recent developments in the study of signal transduction to the nucleus

1997 • 212 citations

Activation of STAT transcription factors in oncogenic tyrosine kinase signaling

1998 • 206 citations

Preassociation of STAT1 with STAT2 and STAT3 in Separate Signalling Complexes Prior to Cytokine Stimulation

1996 • 182 citations

IL‐10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes

1996 • 170 citations

IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo.

1997 • 162 citations

Cellular Requirements for Cytokine Production in Response to the Immunomodulators Imiquimod and S-27609

1995 • 140 citations

The role of interferon regulatory factors in the interferon system and cell growth control

1998 • 134 citations

Effects of a novel topical immunomodulator, imiquimod, on keratinocyte cytokine gene expression.

1994 • 116 citations

Cytokine Expression by Epidermal Cell Subpopulations

1992 • 93 citations

STAT structure and function in signaling

1998 • 91 citations

Structure and Regulation of the Human Interferon Regulatory Factor 1 (IRF-1) and IRF-2 Genes: Implications for a Gene Network in the Interferon System

1994 • 91 citations

Activation of Local Cell-Mediated Immunity in Interferon-Responsive Patients with Human Papillomavirus-Associated Lesions

1996 • 59 citations

Status of Local Cellular Immunity in Interferon-Responsive and -Nonresponsive Human Papillomavirus-Associated Lesions

1996 • 59 citations

STAT protein complexes activated by interferon-γ and gp 130 signaling molecules differ in their sequence preferences and trascriptional induction properties

1995 • 52 citations

Therapy of Human Papillomavirus Infection and Associated Epithelial Tumors

1997 • 49 citations

Skin-Associated Lymphoid Tissue in Human Immunodeficiency Virus-1, Human Papillomavirus, and Herpes Simplex Virus Infections

1995 • 45 citations

Expression of interferon regulatory factor (IRF) genes and response to interferon-α in chronic myeloid leukaemia

1997 • 44 citations

The Immune Response Modifier Imiquimod Requires STAT-1 for induction of Interferon, Interferon-Stimulated Genes, and Interleukin-6

1999 • 37 citations

Gene expression of markers associated with proliferation and differentiation in human keratinocytes cultured from epidermis and from buccal mucosa

1995 • 26 citations

Regulation of the interferon system, immune response and oncogenesis by the transcription factor interferon regulatory factor-1.

1998 • 18 citations

Response to interferon treatment decreases with epidermal dedifferentiation in condylomas

1996 • 8 citations

Imiquimod for genital warts.

1997 • 1 citations