IL‐10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

1995 • 1,960 citations

Interleukin-10

1993 • 1,820 citations

Enhanced DNA-Binding Activity of a Stat3-Related Protein in Cells Transformed by the Src Oncoprotein

1995 • 945 citations

Jaks and Stats in signaling by the cytokine receptor superfamily

1995 • 902 citations

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

1994 • 813 citations

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.

1995 • 675 citations

Signaling Through the Hematopoietic Cytokine Receptors

1995 • 617 citations

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

1994 • 599 citations

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

1993 • 516 citations

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

1993 • 504 citations

IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes.

1995 • 420 citations

The alphas, betas, and kinases of cytokine receptor complexes

1993 • 418 citations

Tyrosine Phosphorylation of DNA Binding Proteins by Multiple Cytokines

1993 • 367 citations

Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors

1994 • 359 citations

Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

1993 • 306 citations

Components of a stat recognition code: Evidence for two layers of molecular selectivity

1995 • 254 citations

A receptor for interleukin 10 is related to interferon receptors.

1993 • 233 citations

Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways.

1995 • 224 citations

Overlapping sites for constitutive and induced DNA binding factors involved in interferon-stimulated transcription.

1989 • 134 citations

Transcriptional regulation of the junB promoter: analysis of STAT-mediated signal transduction.

1995 • 109 citations

Differentiation-Regulated Serine Phosphorylation of STAT1 Promotes GAF Activation in Macrophages

1995 • 101 citations

Cytokine signal transduction and the JAK family of protein tyrosine kinases

1994 • 89 citations

Lipopolysaccharide-dependent induction of IL-10 receptor expression on murine fibroblasts.

1994 • 79 citations

IL-10-induced factors belonging to the p91 family of proteins bind to IFN-gamma-responsive promoter elements.

1994 • 48 citations