An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

A New Generation of Animal Cell Expression Vectors Based on the Semliki Forest Virus Replicon

1991 • 899 citations

Functional Regions of the Envelope Glycoprotein of Human Immunodeficiency Virus Type 1

1987 • 883 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1994 • 701 citations

Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

1977 • 688 citations

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein

1986 • 593 citations

Major Glycoprotein Antigens That Induce Antibodies in AIDS Patients Are Encoded by HTLV-III

1985 • 583 citations

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

1992 • 540 citations

Quantitation of human immunodeficiency virus type 1 infection kinetics

1993 • 516 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Folding and Assembly of Viral Membrane Proteins

1993 • 447 citations

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

1988 • 442 citations

The J. D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors

1986 • 372 citations

Receptors compete for adaptors found in plasma membrane coated pits.

1988 • 366 citations

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein.

1990 • 360 citations

The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis.

1987 • 355 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor.

1989 • 336 citations

The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions

1992 • 320 citations

Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization

1996 • 293 citations

Retrovirus Envelope Glycoproteins

1990 • 276 citations

Interaction of Activated EGF Receptors with Coated Pit Adaptins

1993 • 259 citations

Identification of the Fusion Peptide of Primate Immunodeficiency Viruses

1989 • 250 citations

The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation

1991 • 246 citations

A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pits

1988 • 245 citations

Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity

1992 • 220 citations

Significance of premature stop codons in env of simian immunodeficiency virus

1989 • 220 citations

Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC.

1995 • 190 citations

Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex.

1990 • 190 citations

Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment.

1994 • 188 citations

Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes.

1990 • 185 citations

Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins

1992 • 182 citations

Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells.

1991 • 181 citations

Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4

1988 • 173 citations

Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses

1987 • 167 citations

Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells

1993 • 167 citations

The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a β turn

1991 • 165 citations

Intracellular maturation and transport of the SV5 type II glycoprotein hemagglutinin-neuraminidase: specific and transient association with GRP78-BiP in the endoplasmic reticulum and extensive internalization from the cell surface.

1989 • 159 citations

Rescue of human immunodeficiency virus type 1 matrix protein mutants by envelope glycoproteins with short cytoplasmic domains

1995 • 159 citations

Construction and Characterization of a Retroviral Vector Demonstrating Efficient Expression of Cloned cDNA Sequences

1988 • 157 citations

The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells

1994 • 156 citations

Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase.

1995 • 147 citations

Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein increases env incorporation into particles and fusogenicity and infectivity

1993 • 145 citations

Mutations in the cytoplasmic domain of the influenza virus hemagglutinin affect different stages of intracellular transport.

1985 • 145 citations

Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptor.

1992 • 144 citations

A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells

1995 • 142 citations

A tyrosine-based motif in the cytoplasmic domain of the alphavirus envelope protein is essential for budding.

1994 • 141 citations

Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells.

1991 • 137 citations

Mutations in the cytoplasmic domain of human immunodeficiency virus type 1 transmembrane protein impair the incorporation of Env proteins into mature virions

1993 • 134 citations

Glycoprotein cytoplasmic domain sequences required for rescue of a vesicular stomatitis virus glycoprotein mutant

1989 • 124 citations

Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types

1992 • 122 citations

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

1990 • 121 citations

Phosphorylation-dependent down-modulation of CD4 requires a specific structure within the cytoplasmic domain of CD4

1991 • 120 citations

Cell Fusion Activity of the Simian Immunodeficiency Virus Envelope Protein Is Modulated by the Intracytoplasmic Domain

1993 • 118 citations

Characterization of stable Chinese hamster ovary cells expressing wild-type, secreted, and glycosylphosphatidylinositol-anchored human immunodeficiency virus type 1 envelope glycoprotein

1993 • 113 citations

Site-directed mutations in sindbis virus E2 glycoprotein's cytoplasmic domain and the 6K protein lead to similar defects in virus assembly and budding

1991 • 113 citations

Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein alters the conformation of the external domain

1994 • 103 citations

In vitro binding of the asialoglycoprotein receptor to the beta adaptin of plasma membrane coated vesicles.

1991 • 102 citations

Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells.

1989 • 102 citations

Amino acid sequences Gly-Pro-Leu-Tyr and Asn-Pro-Glu-Tyr in the submembranous domain of the insulin receptor are required for normal endocytosis.

1991 • 101 citations

Truncations of the simian immunodeficiency virus transmembrane protein confer expanded virus host range by removing a block to virus entry into cells

1993 • 99 citations

Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor.

1991 • 93 citations

Assembly of the Matrix Protein of Simian Immunodeficiency Virus into Virus-like Particles

1993 • 91 citations

Postassembly cleavage of a retroviral glycoprotein cytoplasmic domain removes a necessary incorporation signal and activates fusion activity

1994 • 89 citations

The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef

1994 • 89 citations

Cytoplasmic domain requirement for incorporation of a foreign envelope protein into vesicular stomatitis virus

1993 • 86 citations

Incorporation of homologous and heterologous proteins into the envelope of Moloney murine leukemia virus

1994 • 80 citations

Expression and characterization of glycophospholipid-anchored human immunodeficiency virus type 1 envelope glycoproteins

1993 • 75 citations

Subunit interactions of vesicular stomatitis virus envelope glycoprotein stabilized by binding to viral matrix protein

1992 • 73 citations

Effects of Cytoplasmic Domain Length on Cell Surface Expression and Syncytium-Forming Capacity of the Simian Immunodeficiency Virus Envelope Glycoprotein

1994 • 71 citations

Mutational analysis of the envelope gene of Moloney murine leukemia virus

1993 • 67 citations

Endocytosis of the ASGP receptor H1 is reduced by mutation of tyrosine-5 but still occurs via coated pits.

1991 • 62 citations

Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties

1990 • 56 citations

The structure of an endocytosis signal

1992 • 56 citations

Basis for selective incorporation of glycoproteins into the influenza virus envelope

1993 • 54 citations

Chapter 2 Expression of Exogenous Proteins in Mammalian Cells with the Semliki Forest Virus Vector

1994 • 45 citations

Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus

1994 • 44 citations

Mutations in the cytoplasmic tail of influenza A virus neuraminidase affect incorporation into virions

1993 • 43 citations

Synthesis, oligomerization, and biological activity of the human immunodeficiency virus type 2 envelope glycoprotein expressed by a recombinant vaccinia virus

1990 • 43 citations

Analysis of mutations in the envelope gene of moloney murine leukemia virus: Separation of infectivity from superinfection resistance

1991 • 42 citations

Expression of HIV-1 Envelope Glycoproteins by Semliki Forest Virus Vectors

1993 • 42 citations

Role of the fusogenic peptide sequence in syncytium induction and infectivity of human immunodeficiency virus type 2

1992 • 38 citations

The carboxy terminus of human immunodeficiency virus type 1 gp160 limits its proteolytic processing and transport in transfected cell lines

1990 • 37 citations

Ultrastructural Evidence of an Interaction between Env and Gag Proteins during Assembly of HIV Type 1

1995 • 32 citations

Biochemical requirements for the formation of clathrin-and COP-coated transport vesicles

1993 • 31 citations

Role of the cytoplasmic domains of viral glycoproteins in antibody-induced cell surface mobility

1993 • 9 citations

Transport of a lysosomally targeted Rous sarcoma virus envelope glycoprotein involvestransient expression on the cell surface

1995 • 6 citations