Postassembly cleavage of a retroviral glycoprotein cytoplasmic domain removes a necessary incorporation signal and activates fusion activity

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Nucleotide sequence of Mason-Pfizer monkey virus: An immunosuppressive D-type retrovirus

1986 • 342 citations

The T=4 envelope of sindbis virus is organized by interactions with a complementary T=3 capsid

1987 • 337 citations

The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions

1992 • 320 citations

Retrovirus Envelope Glycoproteins

1990 • 276 citations

Altered cytoplasmic domains affect intracellular transport of the vesicular stomatitis virus glycoprotein

1983 • 264 citations

Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein

1994 • 247 citations

Murine leukemia virus maturation: Protease region required for conversion from “immature” to “Mature” core form and for virus infectivity

1985 • 231 citations

Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity

1992 • 220 citations

Differential effects of mutations in three domains on folding, quaternary structure, and intracellular transport of vesicular stomatitis virus G protein.

1988 • 210 citations

Vectors for efficient expression in mammalian fibroblastoid, myeloid and lymphoid cells via transfection or infection

1988 • 170 citations

Quantitative separation of murine leukemia virus proteins by reversed-phase high-pressure liquid chromatography reveals newly described gag and env cleavage products

1984 • 145 citations

Mutations in the cytoplasmic domain of human immunodeficiency virus type 1 transmembrane protein impair the incorporation of Env proteins into mature virions

1993 • 134 citations

Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types

1992 • 122 citations

Complete sequence of the Rous sarcoma virus env gene: identification of structural and functional regions of its product

1983 • 119 citations

Mutants of the Rous sarcoma virus envelope glycoprotein that lack the transmembrane anchor and cytoplasmic domains: analysis of intracellular transport and assembly into virions

1987 • 113 citations

Syncytium-inducing mutations localize to two discrete regions within the cytoplasmic domain of herpes simplex virus type 1 glycoprotein B

1993 • 111 citations

Common Precursor for Rauscher Leukemia Virus gp69/71, p15(E), and p12(E)

1977 • 102 citations

Truncations of the simian immunodeficiency virus transmembrane protein confer expanded virus host range by removing a block to virus entry into cells

1993 • 99 citations

Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport and membrane association of a capsid.

1991 • 92 citations

Synthesis and processing of the transmembrane envelope protein of equine infectious anemia virus

1990 • 88 citations

Cytoplasmic domain requirement for incorporation of a foreign envelope protein into vesicular stomatitis virus

1993 • 86 citations

Spike—nucleocapsid interaction in Semliki Forest virus reconstructed using network antibodies

1988 • 79 citations

Truncation of the carboxy-terminal 28 amino acids of glycoprotein B specified by herpes simplex virus type 1 mutant amb1511-7 causes extensive cell fusion

1993 • 78 citations

A chimeric avian retrovirus containing the influenza virus hemagglutinin gene has an expanded host range

1992 • 77 citations

Polypeptides of Mason-Pfizer monkey virus I. Synthesis and processing of the gag-gene products

1984 • 74 citations

Preassembled capsids of type D retroviruses contain a signal sufficient for targeting specifically to the plasma membrane

1990 • 74 citations

A viral protease-mediated cleavage of the transmembrane glycoprotein of Mason-Pfizer monkey virus can be suppressed by mutations within the matrix protein.

1992 • 67 citations

Role of the Carboxy-Terminal Portion of the HIV-1 Transmembrane Protein in Viral Transmission and Cytopathogenicity

1989 • 66 citations

Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity

1992 • 57 citations

Cytopathic variants of an attenuated isolate of human immunodeficiency virus type 2 exhibit increased affinity for CD4

1991 • 37 citations

Defective assembly and intracellular transport of mutant paramyxovirus hemagglutinin-neuraminidase proteins containing altered cytoplasmic domains

1990 • 37 citations

The cytoplasmic domain of the human T-cell leukemia virus type I envelope can modulate envelope functions in a cell type-dependent manner

1993 • 35 citations

Mutations within the env gene of Mason-Pfizer monkey virus: effects on protein transport and SU-TM association

1992 • 33 citations

Shortened cytoplasmic domain affects intracellular transport but not nuclear localization of a viral glycoprotein.

1990 • 30 citations

Simian retrovirus-D serotype 1 (SRV-1) envelope glycoproteins gp70 and gp20: expression in yeast cells and identification of specific antibodies in sera from monkeys that recovered from SRV-1 infection

1988 • 22 citations

Polypeptides of Mason-Pfizer monkey virus. III. translational order of proteins on the gag and env gene specified precursor polypeptides

1986 • 22 citations

Mutations within the Transmembrane Glycoprotein of Mason—Pfizer Monkey Virus: Loss of SU—TM Association and Effects on Infectivity

1994 • 22 citations

Coordination of cleavage of gag and env gene products of murine leukemia virus: Implications regarding the mechanism of processing

1984 • 11 citations