Retinoid X Receptor:Vitamin D₃ Receptor Heterodimers Promote Stable Preinitiation Complex Formation and Direct 1,25-Dihydroxyvitamin D₃-Dependent Cell-Free Transcription

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

1996 • 922 citations

Nuclear receptor coactivators and corepressors.

1996 • 917 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

1995 • 756 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

Purification and properties of an ATP-dependent nucleosome remodeling factor

1995 • 600 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

Structural determinants of nuclear receptor assembly on DNA direct repeats

1995 • 561 citations

Two nuclear signalling pathways for vitamin D

1993 • 559 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

1996 • 556 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

1991 • 497 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

1990 • 467 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

p53 Transcriptional Activation Mediated by Coactivators TAF _II 40 and TAF _II 60

1995 • 438 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

1996 • 410 citations

Transcriptional Repression of the Interleukin-2 Gene by Vitamin D₃: Direct Inhibition of NFATp/AP-1 Complex Formation by a Nuclear Hormone Receptor

1995 • 399 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

ISWI, a member of the SWl2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor

1995 • 366 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II

1994 • 358 citations

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site.

1987 • 355 citations

Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).

1992 • 354 citations

General Initiation Factors for RNA Polymerase II

1993 • 346 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.

1993 • 328 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

1990 • 313 citations

Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo.

1995 • 313 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.

1993 • 272 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression.

1993 • 262 citations

How different eukaryotic transcriptional activators can cooperate promiscuously

1990 • 261 citations

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

1990 • 255 citations

General requirement for RNA polymerase II holoenzymes in vivo.

1995 • 249 citations

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.

1996 • 244 citations

Transcriptional elongation by RNA polymerase II is stimulated by transactivators

1994 • 243 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

Polymerase II Promoter Activation: Closed Complex Formation and ATP-Driven Start Site Opening

1992 • 220 citations

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

1995 • 212 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

A general mechanism for transcriptional synergy by eukaryotic activators

1995 • 185 citations

Ligand Modulates the Conversion of DNA-Bound Vitamin D₃ Receptor (VDR) Homodimers into VDR-Retinoid X Receptor Heterodimers

1994 • 182 citations

Activator-induced conformational change in general transcription factor TFIIB

1994 • 177 citations

The Vitamin D Receptor Interacts with General Transcription Factor IIB

1995 • 166 citations

Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses.

1993 • 165 citations

Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome

1996 • 165 citations

ATP-Dependent Nucleosome Reconfiguration and Transcriptional Activation from Preassembled Chromatin Templates

1994 • 163 citations

The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIA.

1992 • 160 citations

Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro.

1995 • 160 citations

Chromatin Structure and RNA Polymerase II Connection: Implications for Transcription

1996 • 159 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1996 • 144 citations

Advances in RNA polymerase II transcription

1992 • 144 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

転写因子TF II Bとヒト甲状腺ホルモン受容体βとの結合は標的遺伝子の発現と甲状腺ホルモンによる活性化を仲介する

1993 • 135 citations

Requirement of a corepressor for Dr1-mediated repression of transcription.

1996 • 128 citations

Unliganded Thyroid Hormone Receptor α Can Target TATA-Binding Protein for Transcriptional Repression

1996 • 123 citations

Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation.

1995 • 118 citations

Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation.

1994 • 114 citations

Effects of activation-defective TBP mutations on transcription initiation in yeast

1994 • 110 citations

DNA target selectivity by the vitamin D3 receptor: mechanism of dimer binding to an asymmetric repeat element.

1993 • 110 citations

Modulation of Nuclear Receptor Interactions by Ligands: Kinetic Analysis Using Surface Plasmon Resonance

1996 • 108 citations

Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation.

1994 • 103 citations

Mouse Retinoid X Receptor Contains a Separable Ligand-Binding and Transactivation Domain in Its E Region

1995 • 95 citations

Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF.

1991 • 88 citations

The role of activators in assembly of RNA polymerase II transcription complexes

1994 • 86 citations

In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells.

1994 • 80 citations

Selective Effects of Ligands on Vitamin D₃ Receptor- and Retinoid X Receptor-Mediated Gene Activation In Vivo

1996 • 79 citations

HMG17 is a chromatin-specific transcriptional coactivator that increases the efficiency of transcription initiation.

1995 • 78 citations

TATA-binding Protein Residues Implicated in a Functional Interplay between Negative Cofactor NC2 (Dr1) and General Factors TFIIA and TFIIB

1995 • 76 citations

Transcriptional synergism between the vitamin D3 receptor and other nonreceptor transcription factors.

1994 • 68 citations

TFIIB-Directed Transcriptional Activation by the Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4

1996 • 67 citations

DNA Binding Properties of the Vitamin D₃Receptor Zinc Finger Region

1991 • 65 citations

Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo.

1994 • 65 citations

DNA binding analysis of glucocorticoid receptor specificity mutants

1992 • 65 citations

Interaction of Oct-1 with TFIIB

1995 • 64 citations

Retinoid-dependent in vitro transcription mediated by the RXR/RAR heterodimer.

1994 • 61 citations

Transcriptional activation by the orphan nuclear receptor ARP-1

1995 • 60 citations

Vitamin D3-retinoid X receptor dimerization, DNA binding, and transactivation are differentially affected by analogs of 1,25-dihydroxyvitamin D3.

1995 • 57 citations

Transcriptional Silencing by Unliganded Thyroid Hormone Receptor β Requires a Soluble Corepressor That Interacts with the Ligand-Binding Domain of the Receptor

1996 • 46 citations

Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA.

1996 • 44 citations

Vitamin D receptor interactions with the murine osteopontin response element

1996 • 39 citations

Protease footprinting reveals a surface on transcription factor TFIIB that serves as an interface for activators and coactivators.

1995 • 37 citations

The glucocorticoid receptor hormone binding domain mediates transcriptional activationin vitroin the absence of ligand

1993 • 36 citations

Recombinant thyroid hormone receptor and retinoid Xreceptor stimulate ligand-dependent transcription in vitro.

1994 • 28 citations

The glucocorticoid receptor acts as an antirepressor in receptor-dependent in vitro transcription

1993 • 12 citations