SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

1995 • 756 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Modular structure of a chicken lysozyme silencer: Involvement of an unusual thyroid hormone receptor binding site

1990 • 487 citations

Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding

1994 • 432 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1989 • 387 citations

An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

1995 • 372 citations

Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

1995 • 361 citations

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1994 • 338 citations

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.

1993 • 328 citations

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor.

1992 • 302 citations

The WD repeats of Tup1 interact with the homeo domain protein alpha 2.

1994 • 207 citations

Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants.

1993 • 193 citations

Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

1995 • 167 citations

A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line.

1992 • 160 citations

Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

1995 • 137 citations

Unliganded Thyroid Hormone Receptor α Can Target TATA-Binding Protein for Transcriptional Repression

1996 • 123 citations

Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation.

1995 • 118 citations

Mouse Retinoid X Receptor Contains a Separable Ligand-Binding and Transactivation Domain in Its E Region

1995 • 95 citations

A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes.

1987 • 87 citations

Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor alpha.

1993 • 54 citations

The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.

1990 • 50 citations

Repression Mechanisms of v‐ERBA and Other Members of the Steroid Receptor Superfamily

1993 • 19 citations