Presentation of Antigen by Endothelial Cells and Chemoattraction Are Required for Homing of Insulin-specific CD8+ T Cells

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

T-Cell Function and Migration — Two Sides of the Same Coin

2000 • 1,437 citations

Lymphocyte traffic control by chemokines

2001 • 1,225 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions

1998 • 1,013 citations

Cross-Presentation, Dendritic Cells, Tolerance and Immunity

2001 • 894 citations

Leukocyte adhesion to endothelium in inflammation

1990 • 882 citations

Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

2000 • 723 citations

Lymphocyte Trafficking and Regional Immunity

1999 • 686 citations

The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD

1997 • 685 citations

Regulated expression and binding of three VLA (β1) integrin receptors on T cells

1990 • 634 citations

A mutation in the insulin 2 gene induces diabetes with severe pancreatic β-cell dysfunction in the Mody mouse

1999 • 555 citations

Chemokines Trigger Immediate β2 Integrin Affinity and Mobility Changes

2000 • 517 citations

Epstein-Barr Virus–induced Molecule 1 Ligand Chemokine Is Expressed by Dendritic Cells in Lymphoid Tissues and Strongly Attracts Naive T Cells and Activated B Cells

1998 • 479 citations

BLC Expression in Pancreatic Islets Causes B Cell Recruitment and Lymphotoxin-Dependent Lymphoid Neogenesis

2000 • 450 citations

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library

1999 • 442 citations

The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules

2000 • 420 citations

Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways

1999 • 413 citations

The Ccr7 Ligand ELC (Ccl19) Is Transcytosed in High Endothelial Venules and Mediates T Cell Recruitment

2001 • 367 citations

Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation of P-selectin in vitro.

1996 • 353 citations

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1996 • 349 citations

Coupling of the TCR to Integrin Activation by SLAP-130/Fyb

2001 • 314 citations

Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant

1994 • 301 citations

Recycling MHC class I molecules and endosomal peptide loading

1999 • 290 citations

Neutrophil rolling altered by inhibition of L-selectin shedding in vitro

1996 • 285 citations

Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

2001 • 282 citations

Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: An alternative mechanism of allorecognition

2002 • 231 citations

Vascular addressins are induced on islet vessels during insulitis in nonobese diabetic mice and are involved in lymphoid cell binding to islet endothelium.

1993 • 218 citations

Chemokine Receptor Expression and Function in CD4+ T Lymphocytes with Regulatory Activity

2001 • 218 citations

Cross-primed CD8+ T cells mediate graft rejection via a distinct effector pathway

2002 • 204 citations

Evolution of a Complex T Cell Receptor Repertoire during Primary and Recall Bacterial Infection

1998 • 202 citations

Ectopic Expression of the Murine Chemokines CCL21a and CCL21b Induces the Formation of Lymph Node-Like Structures in Pancreas, But Not Skin, of Transgenic Mice

2002 • 201 citations

Lymphoid Tissue Homing Chemokines Are Expressed in Chronic Inflammation

2000 • 193 citations

CD8 Binding to MHC Class I Molecules Is Influenced by T Cell Maturation and Glycosylation

2001 • 187 citations

Cutting Edge: Ectopic Expression of the Chemokine TCA4/SLC Is Sufficient to Trigger Lymphoid Neogenesis

2000 • 187 citations

Stimulation of integrin-mediated adhesion of T lymphocytes and monocytes: two mechanisms with divergent biological consequences.

1994 • 149 citations

Separable effector T cell populations specialized for B cell help or tissue inflammation

2001 • 138 citations

Human Endothelial Cell Presentation of Antigen and the Homing of Memory/Effector T Cells to Skin

2001 • 116 citations

Mucosal Addressin Is Required for the Development of Diabetes in Nonobese Diabetic Mice

1998 • 115 citations

Antigen Recognition Influences Transendothelial Migration of CD4+ T Cells

1999 • 109 citations

The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between alpha 4-integrins and vascular cell adhesion molecule-1.

1994 • 104 citations

Mapping of murine diabetogenic gene mody on chromosome 7 at D7Mit258 and its involvement in pancreatic islet and beta cell development during the perinatal period.

1998 • 96 citations

IFN-γ Affects Homing of Diabetogenic T Cells

2001 • 94 citations

Multiple Antigen-Specific Processing Pathways for Activating Naive CD8+ T Cells In Vivo

2001 • 90 citations

The Role of CD4 . CD8 T Cells in IDDM

1999 • 75 citations

Positional Cloning and Molecular Characterization of an Immunodominant Cytotoxic Determinant of the Mouse H3 Minor Histocompatibility Complex

1998 • 50 citations

A simple method for culturing mouse vascular endothelium

2001 • 38 citations

Activation-dependent changes in soluble fibronectin binding and expression of β1 integrin activation epitopes in T cells: relationship to T cell adhesion and migration

2000 • 35 citations

Lymphocyte Function Associated Antigen-1, Integrin α4, and L-Selectin Mediate T-Cell Homing to the Pancreas in the Model of Adoptive Transfer of Diabetes in NOD Mice

1996 • 34 citations

The Roles of α4-Integrins in the Development of Insulin-Dependent Diabetes Mellitus

1998 • 23 citations

<b>ENDOTHELIAL AND MICROVASCULAR ABNORMALITIES IN THE ISLET OF NON-OBESE DIABETIC (NOD) MICE: TRANSMISSION AND SCANNING ELECTRON MICROSCOPIC </b><b>STUDIES </b>

1992 • 4 citations