Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion

2000 • 1,167 citations

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

1990 • 799 citations

Complex Complexes: Signaling at the TCR

1996 • 512 citations

Negative Regulation of Fibroblast Motility by Ena/VASP Proteins

2000 • 460 citations

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1998 • 420 citations

Uncoupling of Nonreceptor Tyrosine Kinases from PLC-γ1 in an SLP-76-Deficient T Cell

1998 • 412 citations

Requirement for the Leukocyte-Specific Adapter Protein SLP-76 for Normal T Cell Development

1998 • 405 citations

Impaired Viability and Profound Block in Thymocyte Development in Mice Lacking the Adaptor Protein SLP-76

1998 • 360 citations

Avidity regulation of integrins: the driving force in leukocyte adhesion

2000 • 342 citations

Fyn-Binding Protein (Fyb)/Slp-76–Associated Protein (Slap), Ena/Vasodilator-Stimulated Phosphoprotein (Vasp) Proteins and the Arp2/3 Complex Link T Cell Receptor (Tcr) Signaling to the Actin Cytoskeleton

2000 • 294 citations

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1997 • 265 citations

Molecular Cloning of SLAP-130, an SLP-76-associated Substrate of the T Cell Antigen Receptor-stimulated Protein Tyrosine Kinases

1997 • 238 citations

Signaling Takes Shape in the Immune System

2000 • 237 citations

Adaptors and Molecular Scaffolds in Immune Cell Signaling

1999 • 222 citations

Cbl-b Is a Negative Regulator of Receptor Clustering and Raft Aggregation in T Cells

2000 • 211 citations

INTEGRATION OF T CELL RECEPTOR–DEPENDENT SIGNALING PATHWAYS BY ADAPTER PROTEINS

1999 • 197 citations

Integrins and inside-out signal transduction: converging signals from PKC and PIP3

1997 • 139 citations

α4β1 Integrin/VCAM-1 Interaction Activates αLβ2 Integrin-Mediated Adhesion to ICAM-1 in Human T Cells

2000 • 129 citations

Integrins in the Immune System

1999 • 122 citations

FYN-T-FYB-SLP-76 Interactions Define a T-cell Receptor ζ/CD3-mediated Tyrosine Phosphorylation Pathway That Up-regulates Interleukin 2 Transcription in T-cells

1999 • 98 citations

Novel Isoform of Lymphoid Adaptor FYN-T-binding Protein (FYB-130) Interacts with SLP-76 and Up-regulates Interleukin 2 Production

1999 • 74 citations

Putting on the Brakes

2000 • 68 citations

Functional Association between SLAP-130 and SLP-76 in Jurkat T Cells

2000 • 58 citations

Simulationsstudie zum Einfluß des Sequenzbildungsverfahrens

1999 • 1 citations