Neurogenesis and Apoptotic Cell Death

Molecular characterization of mitochondrial apoptosis-inducing factor

1999 • 4,031 citations

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

1965 • 3,461 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

Navigation-related structural change in the hippocampi of taxi drivers

2000 • 3,075 citations

Running enhances neurogenesis, learning, and long-term potentiation in mice

1999 • 2,829 citations

Neuronal replacement from endogenous precursors in the adult brain after stroke

2002 • 2,731 citations

Chondroitinase ABC promotes functional recovery after spinal cord injury

2002 • 2,236 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

2002 • 1,771 citations

Reduced Apoptosis and Cytochrome c–Mediated Caspase Activation in Mice Lacking Caspase 9

1998 • 1,642 citations

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

2001 • 1,554 citations

Apoptosis in neurodegenerative disorders

2000 • 1,542 citations

Regeneration of Hippocampal Pyramidal Neurons after Ischemic Brain Injury by Recruitment of Endogenous Neural Progenitors

2002 • 1,419 citations

Mitogen-activated protein kinases in apoptosis regulation

2004 • 1,403 citations

Milestones of neuronal development in the adult hippocampus

2004 • 1,389 citations

Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo

1998 • 1,292 citations

For the Long Run

2004 • 1,289 citations

Neurogenesis in the Neocortex of Adult Primates

1999 • 1,268 citations

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

2003 • 1,037 citations

Rat forebrain neurogenesis and striatal neuron replacement after focal stroke

2002 • 1,013 citations

Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain.

1983 • 983 citations

Doublecortin Is a Developmentally Regulated, Microtubule-Associated Protein Expressed in Migrating and Differentiating Neurons

1999 • 974 citations

Increased hippocampal neurogenesis in Alzheimer's disease

2003 • 955 citations

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1998 • 933 citations

Are New Neurons Formed in the Brains of Adult Mammals?

1962 • 930 citations

BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders

2004 • 893 citations

Human marrow stromal cell therapy for stroke in rat

2002 • 858 citations

Isolation, Characterization, and use of Stem Cells from the CNS

1995 • 819 citations

VEGF is necessary for exercise‐induced adult hippocampal neurogenesis

2003 • 801 citations

Neurogenesis in the adult brain: death of a dogma

2000 • 796 citations

Treatment of Stroke With Erythropoietin Enhances Neurogenesis and Angiogenesis and Improves Neurological Function in Rats

2004 • 756 citations

Coordinated Interaction of Neurogenesis and Angiogenesis in the Adult Songbird Brain

2002 • 718 citations

FGF-2-Responsive Neuronal Progenitors Reside in Proliferative and Quiescent Regions of the Adult Rodent Brain

1995 • 691 citations

Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesisin a mouse model

2004 • 685 citations

Efficacy of doublecortin as a marker to analyse the absolute number anddendritic growth of newly generated neurons in the adult dentate gyrus

2004 • 638 citations

Functional significance of adult neurogenesis

2004 • 625 citations

Rapid extension of axons into the CA3 region by adult-generated granule cells

1999 • 597 citations

Attenuation of Delayed Neuronal Death after Mild Focal Ischemia in Mice by Inhibition of the Caspase Family

1998 • 554 citations

Targeting programmed cell death in neurodegenerative diseases

2003 • 535 citations

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

2003 • 532 citations

Adult neurogenesis and neural stem cells of the central nervous system in mammals

2002 • 529 citations

Programmed Cell Death in Cerebral Ischemia

2001 • 471 citations

Post-Natal Origin of Microneurones in the Rat Brain

1965 • 468 citations

Newly generated neurons in the amygdala and adjoining cortex of adult primates

2002 • 459 citations

Bone Marrow-Derived Endothelial Progenitor Cells Participate in Cerebral Neovascularization After Focal Cerebral Ischemia in the Adult Mouse

2002 • 452 citations

FGF-2 regulation of neurogenesis in adult hippocampus after brain injury

2001 • 451 citations

Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APP _Sw,Ind ) mice

2004 • 432 citations

In VivoDelivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

2002 • 418 citations

A critical role of neural-specific JNK3 for ischemic apoptosis

2003 • 395 citations

Crosstalk between Nitric Oxide and Zinc Pathways to Neuronal Cell Death Involving Mitochondrial Dysfunction and p38-Activated K+ Channels

2004 • 390 citations

Neuronal growth, atrophy and death in a sexually dimorphic song nucleus in the zebra finch brain

1985 • 384 citations

Sildenafil (Viagra) Induces Neurogenesis and Promotes Functional Recovery After Stroke in Rats

2002 • 372 citations

Navigation expertise and the human hippocampus: A structural brain imaging analysis

2003 • 357 citations

Radiation injury and neurogenesis

2003 • 329 citations

Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation

2002 • 301 citations

Is it all DNA repair?

2002 • 294 citations

Oxidative neuronal injury

2004 • 266 citations

Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN‐1 antibody treatment in the adult rat

2002 • 248 citations

Akt as a mediator of cell death

2003 • 245 citations

The c-Jun N-Terminal Protein Kinase Signaling Pathway Mediates Bax Activation and Subsequent Neuronal Apoptosis through Interaction with Bim after Transient Focal Cerebral Ischemia

2004 • 232 citations

Neurogenic Effect of -Amyloid Peptide in the Development of Neural Stem Cells

2004 • 228 citations

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

2001 • 211 citations

Effects of Implantation Site of Stem Cell Grafts on Behavioral Recovery From Stroke Damage

2002 • 199 citations

Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

2003 • 193 citations

Dueling Activities of AIF in Cell Death versus Survival

2002 • 186 citations

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

2004 • 183 citations

Selective, Reversible Caspase-3 Inhibitor Is Neuroprotective and Reveals Distinct Pathways of Cell Death after Neonatal Hypoxic-ischemic Brain Injury

2002 • 177 citations

Neuronal replacement in adult brain

2002 • 170 citations

Heat Shock Proteins and Neuroprotection

2003 • 166 citations

Is programmed cell death required for neural tube closure?

1997 • 162 citations

Cell death mechanisms in neurodegeneration

2001 • 160 citations

Characterization of the subventricular zone of the adult human brain: evidence for the involvement of Bcl-2

2000 • 151 citations

Excitotoxins in Neuronal Apoptosis and Necrosis

1999 • 146 citations

Role of semaphorins in the adult nervous system

2003 • 139 citations

Neurogenesis following brain ischemia

2002 • 133 citations

Cell transplantation for stroke

2002 • 133 citations

Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB

2004 • 132 citations

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: Predominant expression in structures of the olfactory-hippocampal pathway and the motor system

1998 • 121 citations

Marked species and age‐dependent differences in cell proliferation and neurogenesis in the hippocampus of wild‐living rodents

2004 • 107 citations

Caspases on the brain

2002 • 106 citations

Apoptosis: Overview and Signal Transduction Pathways

2000 • 102 citations

Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells

2004 • 101 citations

Shutdown of Translation: Lethal or Protective? Unfolded Protein Response versus Apoptosis

2003 • 99 citations

Transient downregulation of sema3a mrna in a rat model for temporal lobe epilepsy A novel molecular event potentially contributing to mossy fiber sprouting

2003 • 96 citations

Environment complexity stimulates visual cortex neurogenesis: death of a dogma and a research career

2001 • 87 citations

Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Deficiency Results in Exencephaly and Is Required for Apoptosis within the Developing CNS

2000 • 86 citations

Alzheimer病トランスジェニック(PDGF‐APPSw,Ind)マウス

2004 • 85 citations

Apaf-1 deficiency and neural tube closure defects are found in fog mice

2001 • 83 citations

Copper-Zinc Superoxide Dismutase Affects Akt Activation After Transient Focal Cerebral Ischemia in Mice

2003 • 77 citations

Apoptosis in acute and chronic neurological disorders

2004 • 69 citations

Growth and atrophy of neurons labeled at their birth in a song nucleus of the zebra finch.

1990 • 61 citations

Evidence for a Postnatal Doubling of Neuron Number in the Developing Human Cerebral Cortex Between 15 Months and 6 Years

1998 • 58 citations

The induction of heat shock proteins as a potential strategy to treat neurodegenerative disorders

2004 • 58 citations

Induction of neuronal type-specific neurogenesis in the cerebral cortex of adult mice: manipulation of neural precursors in situ

2002 • 53 citations

Heat Shock Protein 70 Neutralizes Apoptosis-Inducing Factor

2001 • 29 citations