Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1991 • 2,982 citations

Running enhances neurogenesis, learning, and long-term potentiation in mice

1999 • 2,829 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Vascular niche for adult hippocampal neurogenesis

2000 • 1,805 citations

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

1997 • 1,468 citations

Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat

1993 • 1,215 citations

Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

1998 • 1,135 citations

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

1994 • 986 citations

Estrogen Stimulates a Transient Increase in the Number of New Neurons in the Dentate Gyrus of the Adult Female Rat

1999 • 958 citations

New stereological methods for counting neurons

1993 • 951 citations

The Concept of a Blood-Brain Barrier

1980 • 812 citations

Hippocampal neurogenesis in adult Old World primates

1999 • 804 citations

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

1997 • 789 citations

Continuation of neurogenesis in the hippocampus of the adult macaque monkey

1999 • 765 citations

Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population

1989 • 746 citations

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus

1995 • 738 citations

An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the rat

1975 • 725 citations

Restoring production of hippocampal neurons in old age

1999 • 717 citations

The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall

1995 • 662 citations

Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system

1988 • 604 citations

Rapid extension of axons into the CA3 region by adult-generated granule cells

1999 • 597 citations

Opiates inhibit neurogenesis in the adult rat hippocampus

2000 • 590 citations

Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats

1999 • 531 citations

Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections

1988 • 429 citations

Heterogenous properties of dentate granule neurons in the adult rat

2000 • 415 citations

Cerebral blood flow and metabolism during exercise

2000 • 394 citations

Age-related production of new granule cells in the adult dentate gyrus

1995 • 384 citations

Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway

1997 • 381 citations

Apoptosis and Its Relation to the Cell Cycle in the Developing Cerebral Cortex

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The Concept of a Blood-Brain Barrier

1980 • 347 citations

Implications of the Blood-Brain Barrier and Its Manipulation

1989 • 308 citations

Late DNA Synthesis in Heterochromatin

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BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone

1992 • 241 citations

A family of proteins implicated in axon guidance and outgrowth

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Incorporation of Thymidine and its Analogue, Bromodeoxyuridine, into Embryos and Maternal Tissues of the Mouse

1973 • 151 citations

Exploiting the Dynamics of S-Phase Tracers in Developing Brain: Interkinetic Nuclear Migration for Cells Entering versus Leavingthe S-Phase

2000 • 144 citations

A developmental study of the quantitative distribution of LHRH neurons within the central nervous system of postnatal male and female rats

1986 • 141 citations

Discussion point stem cells and neurogenesis in the adult brain

1998 • 140 citations

Embryonic and Postnatal Injections of Bromodeoxyuridine Produce Age-Dependent Morphological and Behavioral Abnormalities

1999 • 129 citations

Early postmitotic neurons transiently express TOAD‐64, a neural specific protein

1995 • 112 citations

Developmental changes in membrane properties and postsynaptic currents of granule cells in rat dentate gyrus

1996 • 107 citations

Local Homogeneity of Cell Cycle Length in Developing Mouse Cortex

1997 • 86 citations

Neuron numbers in the presubiculum, parasubiculum, and entorhinal area of the rat

1997 • 72 citations

Specificity and Sodium Dependence of the Active Nucleoside Transport System in Choroid Plexus

1984 • 64 citations

Age-related changes of DNA repair and mitochondrial DNA synthesis in the mouse brain

1999 • 62 citations

Proliferation of subependymal cells in the adult primate CNS: differential uptake of DNA labelled precursors.

1983 • 62 citations

Nucleoside transport in choroid plexus: Mechanism and specificity

1982 • 61 citations

Effect of fluorodeoxyuridine, colcemid, and bromodeoxyuridine on developing neocortex of the mouse

1973 • 61 citations

The cellular effect of 5-bromodeoxyuridine on the mammalian embryo

1979 • 57 citations

Expression of EGFR-, p75NGFR-, and PSTAIR (cdc2)-Like Immunoreactivity by Proliferating Cells in the Adult Rat Hippocampal Formation and Forebrain

1996 • 52 citations

Human Neuroblastoma Cell Culture: Effect of 5-Bromodeoxyuridine on Morphological Differentiation and Levels of Neural Enzymes

1973 • 49 citations

Localization and Mechanism of Thymidine Transport in the Central Nervous System

1982 • 48 citations

Statistical confirmation that immunofluorescent detection of DNA repair in human fibroblasts by measurement of bromodeoxyuridine incorporation is stoichiometric and sensitive

1993 • 47 citations

Early and transient increase of rat hippocampal blood-brain barrier permeability to amino acids during kainic acid-induced seizures

1995 • 44 citations

Ontogeny and Phylogeny of the Blood-Brain Barrier

1989 • 43 citations

Postnatal neurogenesis in the cerebellum of the cat and tritiated thymidine autoradiography

1971 • 41 citations

Unscheduled DNA synthesis in various types of cells of the mouse brain in vivo

1989 • 37 citations

Identification of a saturable uptake system for deoxyribonucleosides at the blood-brain and blood-cerebrospinal fluid barriers

1996 • 37 citations

Validation of a flow cytometric in vitro DNA repair (UDS) assay in rat hepatocytes

1994 • 34 citations

The effects of 5‐bromodeoxyuridine on fusion of the cranial neural folds in the mouse embryo

1985 • 34 citations

X-ray dose-effect relationship on unscheduled DNA synthesis and spontaneous unscheduled DNA synthesis in mouse brain cells studied in vivo

1989 • 31 citations

Saturation kinetics, specificity and NBMPR sensitivity of thymidine entry into the central nervous system

1997 • 30 citations

Influence of Sex on the Blood Brain Barrier Permeability During Bicuculline-Induced Seizures

1992 • 27 citations

Histogenesis and dependent glutamine synthetase inducibility in embryonic neural retina. Irreversible inhibition of differentiation by 5-bromodeoxyuridine

1973 • 26 citations

Effects of prenatal exposure to 5-bromo-2′-deoxyuridine on the developing brain and reproductive function in male mouse offspring

1998 • 23 citations

KINETICS OF CELL PROLIFERATION IN THE POSTNATAL RAT DENTATE GYRUS

1978 • 22 citations

Defective transport of thymidine by cultured cells resistant to 5‐bromodeoxyuridine

1977 • 20 citations

Delay of oligodendrocyte differentiation by 5-bromodeoxyuridine (BUdR)

1976 • 16 citations

Quantification of efflux into the blood and brain of intraventricularly perfused [3H]thymidine in the anaesthetized rabbit

1997 • 9 citations