Increased Expression of β6-Integrin in Skin Leads to Spontaneous Development of Chronic Wounds

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1

1999 • 1,965 citations

An Assay for Transforming Growth Factor-β Using Cells Transfected with a Plasminogen Activator Inhibitor-1 Promoter-Luciferase Construct

1994 • 749 citations

Transforming Growth Factor-β Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation

2002 • 622 citations

NEW EMBO MEMBER'S REVIEW: Role of integrins in regulating epidermal adhesion, growth and differentiation

2002 • 616 citations

Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling

1995 • 470 citations

Mechanisms of tissue repair: from wound healing to fibrosis

1997 • 453 citations

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis

2000 • 415 citations

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.

1989 • 365 citations

Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.

1995 • 324 citations

Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing.

1993 • 319 citations

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.

1996 • 312 citations

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

1995 • 303 citations

Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.

1992 • 292 citations

Cell biology of gingival wound healing

2000 • 284 citations

Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.

1994 • 250 citations

Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds.

1994 • 238 citations

Normal Development, Wound Healing, and Adenovirus Susceptibility in β5-Deficient Mice

2000 • 214 citations

Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization.

1989 • 193 citations

A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis

2001 • 164 citations

Keratinocytes in Human Wounds Express αvβ6 Integrin

1996 • 160 citations

Differential Effects of the Integrins α9β1, αvβ3, and αvβ6 on Cell Proliferative Responses to Tenascin

1996 • 141 citations

Tissue- and stratum-specific expression of the human involucrin promoter in transgenic mice.

1993 • 141 citations

Inflammation in Nonhealing Diabetic Wounds

2001 • 139 citations

Cell biology of gingival wound healing

2000 • 116 citations

Epidermal Regulation of Dermal Fibroblast Activity

1998 • 106 citations

Re-epithelialization of normal human excisional wounds is associated with a switch from alpha v beta 5 to alpha v beta 6 integrins.

1996 • 97 citations

Active Transforming Growth Factor-β in Wound Repair

1999 • 96 citations

Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor alpha and transforming growth factor beta.

1997 • 83 citations

Expression of the Human Integrin β 6 Subunit in Alveolar Type II Cells and Bronchiolar Epithelial Cells Reverses Lung Inflammation in β 6 Knockout Mice

1998 • 76 citations

Function of Cytokines within the TGF-β Superfamily as Determined from Transgenic and Gene Knockout Studies in Mice

2002 • 71 citations

Immunolocalization of Tenascin-C, α9 Integrin Subunit, and αvβ6 Integrin During Wound Healing in Human Oral Mucosa

2000 • 69 citations

Different integrins mediate cell spreading, haptotaxis and lateral migration of HaCaT keratinocytes on fibronectin

1999 • 66 citations

Re-epithelialization of normal human excisional wounds is associated with a switch from αvβ5 to αvβ6 integrins

1996 • 64 citations

Enteric Expression of the Integrin αvβ6 Is Essential for Nematode-Induced Mucosal Mast Cell Hyperplasia and Expression of the Granule Chymase, Mouse Mast Cell Protease-1

2002 • 49 citations

Development, characterization, and wound healing of the keratin 14 promoted transforming growth factor‐β1 transgenic mouse

2002 • 49 citations

Keratinocytes Inhibit Expression of Connective Tissue Growth Factor in Fibroblasts In Vitro by an Interleukin-1α-Dependent Mechanism

2002 • 42 citations

The Selective Regulation of αVβ1 Integrin Expression Is Based on the Hierarchical Formation of αV-containing Heterodimers

2002 • 35 citations

Wound fluids mediate granulation tissue growth phases

1983 • 22 citations

Monocyte Chemotactic Protein-1 (MCP-1) mRNA is Down-Regulated in Human Dermal Fibroblasts by Dexamethasone: Differential Regulation by TGF-β

1995 • 20 citations

Latent and Active Transforming Growth Factor β1 Released from Genetically Modified Keratinocytes Modulates Extracellular Matrix Expression by Dermal Fibroblasts in a Coculture System

2002 • 18 citations

Healing of open wounds: effects of oxygen, disturbed blood supply and hyperemia by infrared irradiation.

1971 • 13 citations

Tensile strength testing methodology for partially healed rat skin wounds: engineering considerations.

1971 • 3 citations