The Selective Regulation of αVβ1 Integrin Expression Is Based on the Hierarchical Formation of αV-containing Heterodimers

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 672 citations

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization.

1989 • 627 citations

Role of the alpha v beta 3 integrin in human melanoma cell invasion.

1992 • 414 citations

A novel fibronectin receptor with an unexpected subunit composition (alpha v beta 1).

1990 • 300 citations

Integrin α2β1 Is a Positive Regulator of Collagenase (MMP-1) and Collagen α1(I) Gene Expression

1995 • 281 citations

Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody.

1993 • 269 citations

The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line.

1990 • 251 citations

Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.

1994 • 250 citations

A Biochemical Characterization of the Binding of Osteopontin to Integrins αvβ1 and αvβ5

1995 • 245 citations

Interactions between Growth Factors and Integrins: Latent Forms of Transforming Growth Factor-β Are Ligands for the Integrin αvβ1

1998 • 229 citations

A developmental analysis of oligodendroglial integrins in primary cells: changes in αv-associated β subunits during differentiation

1994 • 209 citations

Integrin αvβ1 Is an Adenovirus Coreceptor

2001 • 198 citations

The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin

1993 • 188 citations

A Role in Migration for the αvβ1 Integrin Expressed on Oligodendrocyte Precursors

1996 • 178 citations

Integrin αvβ1 Is a Receptor for Foot-and-Mouth Disease Virus

2002 • 173 citations

Specific roles of the αVβ1, αVβ3 and αVβ5 integrins in avian neural crest cell adhesion and migration on vitronectin

1994 • 161 citations

Use of the monoclonal antibody 12F1 to characterize the differentiation antigen VLA-2.

1987 • 154 citations

Transforming growth factor beta differentially regulates expression of integrin subunits in guinea pig airway epithelial cells.

1992 • 116 citations

Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the alpha subunit of the receptor.

1995 • 96 citations

Human Parechovirus 1 Utilizes Integrins αvβ3 and αvβ1 as Receptors

2000 • 93 citations

Studies in Vitro on the Role of αv and β1 Integrins in the Adhesion of Human Dermal Fibroblasts to Provisional Matrix Proteins Fibronectin, Vitronectin, and Fibrinogen

1996 • 82 citations

Collagen XVII Is Destabilized by a Glycine Substitution Mutation in the Cell Adhesion Domain Col15

2000 • 62 citations

Integrins α5β1, αvβ1, and αvβ6 Collaborate in Squamous Carcinoma Cell Spreading and Migration on Fibronectin

2000 • 57 citations

Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.

1992 • 51 citations

The Cell Adhesion Domain of Type XVII Collagen Promotes Integrin-mediated Cell Spreading by a Novel Mechanism

2001 • 51 citations

Developmental Regulation of αv Integrins Produces Functional Changes in Astrocyte Behavior

2001 • 41 citations

Vitronectin regulates smooth muscle contractility via αv and β1 integrin(s)

1998 • 39 citations

Up-regulated expression of the β3 integrin and the 92-kDa gelatinase in human HT-144 melanoma cell tumors grown in nude mice

1996 • 29 citations

Depletion of αV integrins from osteosarcoma cells by intracellular antibody expression induces bone differentiation marker genes and suppresses gelatinase (MMP-2) synthesis

1999 • 24 citations

Isolation from Cultured Porcine Gingival Explants of a Neutral Proteinase with Collagen Telopeptidase Activity

1986 • 12 citations