Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is

1975 • 4,443 citations

Three clonal types of keratinocyte with different capacities for multiplication.

1987 • 1,271 citations

Growth of cultured human epidermal cells into multiple epithelia suitable for grafting.

1979 • 1,248 citations

Transforming growth factor-beta in disease: the dark side of tissue repair.

1992 • 1,126 citations

Permanent coverage of large burn wounds with autologous cultured human epithelium

1985 • 1,022 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Transforming growth factor-beta: recent progress and new challenges.

1992 • 781 citations

Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes

1991 • 771 citations

Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor

1987 • 703 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 672 citations

Epidermal differentiation: the bare essentials.

1990 • 651 citations

The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.

1990 • 629 citations

Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms.

1989 • 591 citations

Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

1991 • 574 citations

Location of stem cells of human hair follicles by clonal analysis

1994 • 521 citations

Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.

1990 • 486 citations

Distinct functions for integrins alpha 3 beta 1 in focal adhesions and alpha 6 beta 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes.

1990 • 462 citations

Focal adhesion kinase (p125FAK): A point of convergence in the action of neuropeptides, integrins, and oncogenes

1992 • 453 citations

Growth factors and wound healing: Part II. Role in normal and chronic wound healing

1993 • 451 citations

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells.

1993 • 409 citations

Expression of integrins and basement membrane components by wound keratinocytes.

1993 • 402 citations

Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model.

1991 • 355 citations

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts.

1988 • 340 citations

Novel function for beta 1 integrins in keratinocyte cell-cell interactions.

1990 • 338 citations

The α6β4 Integrin Is a Receptor for both Laminin and Kalinin

1994 • 315 citations

Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes

1991 • 307 citations

Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.

1992 • 292 citations

Evidence for an Epidermal Cytokine Network

1990 • 278 citations

Terminal differentiation of epidermal keratinocytes

1989 • 273 citations

Extracellular matrix regulates expression of the TGF-beta 1 gene.

1993 • 260 citations

The keratinocyte as differentiated cell type.

1980 • 260 citations

Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state

1989 • 257 citations

Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors.

1994 • 252 citations

Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.

1994 • 250 citations

TGF-β1 Stimulates Expression of Keratinocyte Integrins During Re-Epithelialization of Cutaneous Wounds

1994 • 246 citations

Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues.

1993 • 240 citations

Direct evidence for spatial and temporal regulation of transforming growth factor β1 expression during cutaneous wound healing

1991 • 230 citations

Cell surface distribution of fibronectin and vitronectin receptors depends on substrate composition and extracellular matrix accumulation.

1988 • 228 citations

A function for the integrin alpha 6 beta 4 in the hemidesmosome.

1991 • 225 citations

Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo.

1993 • 224 citations

Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas.

1989 • 221 citations

Polarized integrin mediates human keratinocyte adhesion to basal lamina.

1990 • 216 citations

Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.

1993 • 210 citations

Polarized expression of integrin receptors (alpha 6 beta 4, alpha 2 beta 1, alpha 3 beta 1, and alpha v beta 5) and their relationship with the cytoskeleton and basement membrane matrix in cultured human keratinocytes.

1991 • 203 citations

Integrin expression during human epidermal development in vivo and in vitro

1991 • 203 citations

Human keratinocyte growth factor effects in a porcine model of epidermal wound healing.

1993 • 200 citations

Distinctive Integrin Expression in the Newly Forming Epidermis During Wound Healing in Humans

1993 • 200 citations

Transforming growth factor-β switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin

1989 • 199 citations

Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

1990 • 195 citations

Nerve growth factor binds to normal human keratinocytes through high and low affinity receptors and stimulates their growth by a novel autocrine loop.

1993 • 187 citations

Integrins and Their Ligands

1993 • 187 citations

Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor.

1994 • 185 citations

Transforming growth factor β regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts

1988 • 185 citations

Growth-regulated synthesis and secretion of biologically active nerve growth factor by human keratinocytes.

1991 • 176 citations

Spatial and temporal patterns of immunoreactive transforming growth factor beta 1, beta 2, and beta 3 during excisional wound repair.

1993 • 176 citations

Fate of human keratinocytes during reepithelialization in an organotypic culture model.

1994 • 169 citations

Integrin VLA-3: ultrastructural localization at cell-cell contact sites of human cell cultures.

1989 • 163 citations

Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model.

1991 • 159 citations

In vitro paracrine regulation of human keratinocyte growth by fibroblast‐derived insulin‐like growth factors

1992 • 156 citations

Human epithelial cells induce human melanocyte growth in vitro but only skin keratinocytes regulate its proper differentiation in the absence of dermis.

1988 • 153 citations

Signaling by integrins: implications for tumorigenesis.

1993 • 150 citations

Motility of fibronectin receptor-deficient cells on fibronectin and vitronectin: collaborative interactions among integrins [published erratum appears in J Cell Biol 1992 Jul;118(1):217]

1992 • 143 citations

EVIDENCE THAT HUMAN ORAL EPITHELIUM RECONSTITUTED IN VITRO AND TRANSPLANTED ONTO PATIENTS WITH DEFECTS IN THE ORAL MUCOSA RETAINS PROPERTIES OF THE ORIGINAL DONOR SITE1

1990 • 134 citations

Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin.

1992 • 134 citations

TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells.

1990 • 129 citations

Proteolytic processing of endogenous and recombinant beta 4 integrin subunit.

1992 • 128 citations

TGF‐β_S and TGF‐β type II receptor in human epidermis: Differential expression in acute and chronic skin wounds

1993 • 122 citations

Treatment of Posterior Hypospadias by the Autologous Graft of Cultured Urethral Epithelium

1990 • 112 citations

Epidermal growth factor receptor distribution in burn wounds. Implications for growth factor-mediated repair.

1992 • 107 citations

Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues.

1993 • 94 citations

Hemidesmosomes: Extracellular Matrix/Intermediate Filament Connectors

1994 • 93 citations

Transforming Growth Factor-β Stimulates the Expression of Fibronectin by Human Keratinocytes

1988 • 87 citations

Biochemical evidence for a homophilic interaction of the alpha 3 beta 1 integrin.

1993 • 84 citations

Role of Transforming Growth Factor Beta in the Maturation of Human Epidermal Keratinocytes

1988 • 82 citations

Integrins of normal human epidermis: differential expression, synthesis and molecular structure

1990 • 81 citations

Transforming growth factor-beta stimulates collagen VII expression by cutaneous cells in vitro.

1992 • 75 citations

Treatment of leg ulcers with cryopreserved allogeneic cultured epithelium. A multicenter study.

1992 • 69 citations

Expression and Topography of Integrins and Basement Membrane Proteins in Epidermal Carcinomas: Basal but not Squamous Cell Carcinomas Display Loss of ∝6β4 and BM-600/Nicein

1993 • 66 citations

Pattern Formation by Cultured Human Epidermal Cells: Development of Curved Ridges Resembling Dermatoglyphs

1978 • 66 citations

Environment‐dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor‐beta

1989 • 54 citations

The Basement Membrane Protein BM-600/Nicein Codistributes with Kalinin and the Integrin α6β4 in Human Cultured Keratinocytes

1993 • 52 citations

Expression of integrin receptors and their role in adhesion, spreading and migration of normal human melanocytes

1993 • 52 citations

VLA protein expression on epidermal cells (keratinocytes, Langerhans cells, melanocytes): a light and electron microscopic immunohistochemical study

1991 • 50 citations

Epidermis as a Secretory Tissue: An In Vitro Tissue Model to Study Keratinocyte Secretion

1994 • 48 citations

Culture of human epithelium

1992 • 36 citations

The size of the intracellular β 1-integrin precursor pool regulates maturation of β 1-integrin subunit and associated α-subunits

1994 • 31 citations

The control of polarized integrin topography and the organization of adhesion-related cytoskeleton in normal human keratinocytes depend upon number of passages in culture and ionic environment

1992 • 29 citations

Transforming Growth Factor-β Modulates Plasminogen Activator Activity and Plasminogen Activator Inhibitor Type-1 Expression in Human Keratinocytes In Vitro

1990 • 28 citations

Psoriatic lesions in patients with chronic liver disease are distinct from psoriasis vulgaris lesions, as judged on basis of integrin adhesion receptors

1994 • 22 citations

Identification and Characterization of Novel Airway Epithelial Integrins

1993 • 17 citations

Psoriatic lesions in patients with chronic liver disease are distinct from psoriasis vulgaris lesions, as judged on basis of integrin adhesion receptors

1994 • 15 citations